NMN
NMN (Nicotinamide Mononucleotide)
📖 핵심 요약
📖 30편 · 15분 읽기NMN은(는) 항산화 계열 보충제입니다. 주로 혈압, 근육 분야에서 연구되었으며, PubMed에 30편의 관련 논문이 있습니다.
🔍 연구 분야별 근거
* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)
📊 효과 크기 분포 (Forest plot)
각 연구의 효과 추정치와 95% 신뢰구간. 개별 연구를 통합(pooling)하지 않고 그대로 표시합니다.
📚 관련 논문 (30편) · 📊 정량 근거 3건
1. Nutrients. 2026 Mar 11;18(6):890. doi: 10.3390/nu18060890. Effects of Nicotinamide Mononucleotide Supplementation on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Zhang M(1), Chen Y(1), Jiang N(1), Zeng J(1), Zhang J(1), Wu C(1), Liu Y(1), Nie Z(1), Ya
2. Ageing Res Rev. 2026 Apr;116:103057. doi: 10.1016/j.arr.2026.103057. Epub 2026 Feb 6. NAD⁺ supplementation for anti-aging and wellness: A PRISMA-guided systematic review of preclinical and clinical evidence. Gallagher C(1), Emmanuel OO(2). Author information: (1)Allure Management, 150 Allend
3. J Assist Reprod Genet. 2026 Jan;43(1):51-65. doi: 10.1007/s10815-025-03720-1. Epub 2025 Oct 29. NMN supplementation as a strategy to improve oocyte quality: a systematic review and transcriptomic analysis. Noh H(1), Sen Gupta S(1), Seshadri S(1), Viñals Gonzalez X(2)(3). Author information:
4. J Cachexia Sarcopenia Muscle. 2025 Jun;16(3):e13799. doi: 10.1002/jcsm.13799. The Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta-Analysis. Prokopidis K(1), Moriarty F(2), Bahat G(3), McLean J(4), Church DD(5), Patel HP(6)(
5. Curr Diab Rep. 2024 Nov 12;25(1):4. doi: 10.1007/s11892-024-01557-z. Effects of Nicotinamide Mononucleotide on Glucose and Lipid Metabolism in Adults: A Systematic Review and Meta-analysis of Randomised Controlled Trials. Chen F(#)(1), Zhou D(#)(1), Kong AP(2), Yim NT(3), Dai S(4)(5)(6), Chen
6. J Alzheimers Dis. 2024;101(s1):S467-S477. doi: 10.3233/JAD-231277. Supplementation with NAD+ Precursors for Treating Alzheimer's Disease: A Metabolic Approach. Alghamdi M(1)(2), Braidy N(1). Author information: (1)Centre for Healthy Brain Ageing, School of Psychiatry, University of New South
7. Curr Pharm Biotechnol. 2025;26(13):2141-2152. doi: 10.2174/0113892010306242240808094303. Effects of Nicotinamide Mononucleotide Supplementation on Muscle and Liver Functions Among the Middle-aged and Elderly: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Wang JP(1)(2
8. Crit Rev Food Sci Nutr. 2025;65(22):4382-4400. doi: 10.1080/10408398.2024.2387324. Epub 2024 Aug 8. Efficacy of oral nicotinamide mononucleotide supplementation on glucose and lipid metabolism for adults: a systematic review with meta-analysis on randomized controlled trials. Zhang J(1), Poo
9. Front Public Health. 2023 Oct 26;11:1287421. doi: 10.3389/fpubh.2023.1287421. eCollection 2023. Exercise training upregulates intracellular nicotinamide phosphoribosyltransferase expression in humans: a systematic review with meta-analysis. Sun X(1), Su L(2)(3), Bu T(1)(3), Zhang Y(4). Auth
10. Exp Gerontol. 2020 Apr;132:110831. doi: 10.1016/j.exger.2020.110831. Epub 2020 Jan 7. NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis. Braidy N(1), Liu Y(2). Author information: (1)Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wal
11. J Int Soc Sports Nutr. 2026 Dec 31;23(1):2632284. doi: 10.1080/15502783.2026.2632284. Epub 2026 Feb 18. Anti-inflammatory effects of nicotinamide mononucleotide (NMN) in human skeletal muscle after BFR-exercise. Yang DL(1), Chao KC(2), Yang HT(1)(2), Chen KH(1), Dewi L(3), Condello G(4), Ye
12. Nat Metab. 2026 Jan;8(1):62-73. doi: 10.1038/s42255-025-01421-8. Epub 2026 Jan 15. The differential impact of three different NAD(+) boosters on circulatory NAD and microbial metabolism in humans. Christen S(1), Redeuil K(1), Goulet L(1), Giner MP(1), Breton I(1), Rota R(1), Frézal A(1), Na
13. Geroscience. 2024 Oct;46(5):4671-4688. doi: 10.1007/s11357-024-01204-1. Epub 2024 May 24. Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study. Morif
14. Sci Rep. 2023 Feb 16;13(1):2786. doi: 10.1038/s41598-023-29787-3. Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial. Katayoshi T(1), Uehata S(1), Nakashima N(1)
15. J Clin Endocrinol Metab. 2023 Jul 14;108(8):1968-1980. doi: 10.1210/clinem/dgad027. Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study. Pencina KM(1), Valderrabano R(1), Wipper B(1), Orkaby AR(2), Reid KF(1), Storer T(1),
13. Geroscience. 2023 Feb;45(1):29-43. doi: 10.1007/s11357-022-00705-1. Epub 2022 Dec 8. The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clini
4. Geriatr Gerontol Int. 2023 Jan;23(1):38-43. doi: 10.1111/ggi.14513. Epub 2022 Nov 28. Effects of nicotinamide mononucleotide on older patients with diabetes and impaired physical performance: A prospective, placebo-controlled, double-blind study. Akasaka H(1), Nakagami H(2), Sugimoto K(3), Y
46. Sci Rep. 2022 Aug 24;12(1):14442. doi: 10.1038/s41598-022-18272-y. Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women. Fukamizu Y(1), Uchida Y(1), Shigekawa A(1), Sato T(1), Kosaka H(2), Sakurai T(3). Author information: (1)Research and Dev
29. Nutrients. 2022 Feb 11;14(4):755. doi: 10.3390/nu14040755. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Kim M(1), Seol J(2)(3)(4), Sato T(5), Fukamizu
6. J Gerontol A Biol Sci Med Sci. 2023 Jan 26;78(1):90-96. doi: 10.1093/gerona/glac049. MIB-626, an Oral Formulation of a Microcrystalline Unique Polymorph of β-Nicotinamide Mononucleotide, Increases Circulating Nicotinamide Adenine Dinucleotide and its Metabolome in Middle-Aged and Older Adults
25. Microorganisms. 2026 Apr 16;14(4):897. doi: 10.3390/microorganisms14040897. High-Level Production of NMN in Escherichia coli Through Co-Utilization of Glucose and Glycerol. Gan J(1)(2), Chen X(1), He Y(1), Zhang Y(3), Zhong J(1)(2), Dong Z(1). Author information: (1)State Key Laboratory of M
45. Redox Biol. 2026 Apr 24;93:104191. doi: 10.1016/j.redox.2026.104191. Online ahead of print. An integrated anti-aging framework targeting NAD(+) homeostasis, mitochondrial quality control, and redox stability: Roles of NMN/NR, PQQ, and EGT. Sun Y(1), Han JC(1), Tran K(1), Pham T(2), Zhou Q(3)
11. Nat Med. 2026 Apr 29. doi: 10.1038/s41591-026-04366-x. Online ahead of print. Low-dose oral nicotinamide mononucleotide for immune thrombocytopenia: a phase 1/2 trial. Li H(#)(1)(2), Xu Y(#)(1)(2), Chen Y(#)(1)(2), Ji L(#)(1)(2), Xu Y(#)(1)(2), Zheng W(1)(2), Sun T(1)(2), Fu R(1)(2), Pei X(1
46. J Nanobiotechnology. 2026 Apr 27. doi: 10.1186/s12951-026-04445-8. Online ahead of print. ROS-responsive microneedle patch delivering NMN@Cu/CeO₂ nanozyme for restoring immune microenvironment and mitochondrial homeostasis to potentiate diabetic wound healing. Wang Y(#)(1), Liang Z(#)(2), X
38. J Nutr Biochem. 2026 Apr 23:110390. doi: 10.1016/j.jnutbio.2026.110390. Online ahead of print. A Potential Anti-Aging Probiotic: Lactobacillus paracasei JS-3 Extends Lifespan in Caenorhabditis elegans and Modulates the Gut Microbiota in the Elderly. Li A(1), Li H(1), Yang L(1), Zhang N(1), W
4. J Anim Sci Biotechnol. 2026 Apr 23;17(1):76. doi: 10.1186/s40104-026-01398-8. Histone lactylation maintains bovine early embryo development via regulating embryonic genome activation. Yu W(#)(1), Xia Y(#)(1), Wang W(1), Yang Z(1), Liu Z(1), Gan X(1), Zhang M(1), Zhou B(1), Li Y(1), Zhang Y(2)
18. Drug Des Devel Ther. 2026 Apr 15;20:594895. doi: 10.2147/DDDT.S594895. eCollection 2026. SRN-901, a Novel Longevity Drug, Extends Lifespan and Healthspan by Targeting Multiple Aging Pathways. Weiss B(1), Miranda DR(1), Arrazati D(1), Cao R(1), Chen J(2)(3), Liu Y(3)(4), Brown D(1), Marshall
34. Pharm Sci Adv. 2026 Feb 12;4:100111. doi: 10.1016/j.pscia.2026.100111. eCollection 2026 Dec. NAD(+) precursor supplementation reverses CD36-mediated lipid accumulation and ferroptosis to restore antitumor function of NK cells in DLBCL. Shi L(1), Huang X(1), Han X(2), Ning C(2), Zhao X(2), Li
20. bioRxiv [Preprint]. 2026 Apr 8:2026.04.07.716846. doi: 10.64898/2026.04.07.716846. Structural and biochemical characterization of a novel inhibitor of NMNAT1, the gatekeeper of nuclear NAD(+) biosynthesis. Lansiquot C(1), Wu R(1), Davies JP(1), Song X(1)(2)(3), Kaniskan HÜ(1)(2)(3), Jin J(1
46. Nutr Res Pract. 2026 Apr;20(2):220-238. doi: 10.4162/nrp.2026.20.2.220. Epub 2025 Jul 23. Nicotinamide mononucleotide attenuates hepatic endoplasmic reticulum stress and modulates circadian rhythms in young mice with diet-induced obesity. Kwon SY(1)(2), Na K(1)(2), Han Y(1)(2), Song S(1)(2),
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