← 전체 보충제 목록

제아잔틴

Zeaxanthin

📑 PubMed 30편 🛡️ 항산화 🗓️ 최신 2026
🔬 메타분석 8 🧪 RCT 7

📖 핵심 요약

📖 30편 · 15분 읽기

제아잔틴은(는) 항산화 계열 보충제입니다. 주로 항산화 분야에서 연구되었으며, PubMed에 30편의 관련 논문이 있습니다.

🔍 연구 분야별 근거

항산화 논문 4편

* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)

📊 효과 크기 분포 (Forest plot)

각 연구의 효과 추정치와 95% 신뢰구간. 개별 연구를 통합(pooling)하지 않고 그대로 표시합니다.

402927600.49 (0.29–0.81)349951510.45 (0.32–0.65)306245840.81 (0.71–0.92)0.215RR (favours ← / →)

📚 관련 논문 (30편) · 📊 정량 근거 6건

1.
📄 연구
Lutein and zeaxanthin for reducing morbidity and mortality in preterm infants.
The Cochrane database of systematic reviews 2025 PMID:40292760
📊 RR 0.49 (95% CI 0.29–0.81)

1. Cochrane Database Syst Rev. 2025 Apr 28;4(4):CD012178. doi: 10.1002/14651858.CD012178.pub2. Lutein and zeaxanthin for reducing morbidity and mortality in preterm infants. Choo YM(1), Yip KX(2), Fiander M(3), Ahmad Kamar A(1), Kamalden TA(4), Tan K(5)(6), Lai NM(7). Author information: (1)Dep

2.
🔬 메타분석
Effect of Antioxidant Supplementation on Macular Pigment Optical Density and Visual Functions: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.
Advances in nutrition (Bethesda, Md.) 2024 PMID:38582248

2. Adv Nutr. 2024 May;15(5):100216. doi: 10.1016/j.advnut.2024.100216. Epub 2024 Apr 4. Effect of Antioxidant Supplementation on Macular Pigment Optical Density and Visual Functions: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Hu W(1), Seah V(1), Huang V(1), K

3.
🔬 메타분석
The effect of lutein and Zeaxanthine on dyslipidemia: A meta-analysis study.
Prostaglandins & other lipid mediators 2023 PMID:36336325
📊 MD -3.82 (95% CI -13.83–6.18)

3. Prostaglandins Other Lipid Mediat. 2023 Feb;164:106691. doi: 10.1016/j.prostaglandins.2022.106691. Epub 2022 Nov 3. The effect of lutein and Zeaxanthine on dyslipidemia: A meta-analysis study. Ghasemi F(1), Navab F(2), Rouhani MH(2), Amini P(1), Shokri-Mashhadi N(3). Author information: (1)Nu

4.
🔬 메타분석
The Effect of Dietary Supplementations on Delaying the Progression of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis.
Nutrients 2022 PMID:36296956
📊 SMD -1.99 (95% CI -3.33–-0.65) · n=5634

4. Nutrients. 2022 Oct 13;14(20):4273. doi: 10.3390/nu14204273. The Effect of Dietary Supplementations on Delaying the Progression of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis. Csader S(1), Korhonen S(2), Kaarniranta K(3)(4), Schwab U(1)(5). Author information: (1)S

5.
🔬 메타분석
Efficacy of different nutrients in age-related macular degeneration: A systematic review and network meta-analysis.
Seminars in ophthalmology 2022 PMID:34995151
📊 RR 0.45 (95% CI 0.32–0.65) · n=85321

5. Semin Ophthalmol. 2022 May 19;37(4):515-523. doi: 10.1080/08820538.2021.2022165. Epub 2022 Jan 7. Efficacy of different nutrients in age-related macular degeneration: A systematic review and network meta-analysis. Li SS(1), Wang HH(2), Zhang D(1). Author information: (1)Department of Ophthal

6.
🔬 메타분석
The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis.
Advances in nutrition (Bethesda, Md.) 2021 PMID:34157098

6. Adv Nutr. 2021 Dec 1;12(6):2244-2254. doi: 10.1093/advances/nmab071. The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis. Wilson LM(1), Tharmarajah S(1), Jia Y(2), Semba RD(3)(4), Schaumberg DA(5)(6), Robinson KA(1)(2). Autho

7.
🔬 메타분석
Carotenoids supplementation and inflammation: a systematic review and meta-analysis of randomized clinical trials.
Critical reviews in food science and nutrition 2022 PMID:33998846

7. Crit Rev Food Sci Nutr. 2022;62(29):8161-8177. doi: 10.1080/10408398.2021.1925870. Epub 2021 May 17. Carotenoids supplementation and inflammation: a systematic review and meta-analysis of randomized clinical trials. Hajizadeh-Sharafabad F(1)(2), Zahabi ES(3), Malekahmadi M(4), Zarrin R(5), A

8.
🔬 메타분석
The effect of Saffron supplementation on waist circumference, HA1C, and glucose metabolism: A systematic review and meta-analysis of randomized clinical trials.
Complementary therapies in medicine 2020 PMID:32147057
📊 MD -2.18 (95% CI -4.05–-0.32) · n=595

8. Complement Ther Med. 2020 Mar;49:102298. doi: 10.1016/j.ctim.2020.102298. Epub 2020 Jan 7. The effect of Saffron supplementation on waist circumference, HA1C, and glucose metabolism: A systematic review and meta-analysis of randomized clinical trials. Rahmani J(1), Bazmi E(2), Clark C(3), Has

9.
🔬 메타분석
Lutein supplementation and retinopathy of prematurity: a meta-analysis.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PMID:32041442

9. J Matern Fetal Neonatal Med. 2022 Jan;35(1):175-180. doi: 10.1080/14767058.2020.1712700. Epub 2020 Feb 10. Lutein supplementation and retinopathy of prematurity: a meta-analysis. Cota F(1), Costa S(1), Giannantonio C(1), Purcaro V(1), Catenazzi P(1), Vento G(1). Author information: (1)Depart

10.
📄 연구
Dietary vitamin and carotenoid intake and risk of age-related cataract.
The American journal of clinical nutrition 2019 PMID:30624584
📊 RR 0.81 (95% CI 0.71–0.92)

10. Am J Clin Nutr. 2019 Jan 1;109(1):43-54. doi: 10.1093/ajcn/nqy270. Dietary vitamin and carotenoid intake and risk of age-related cataract. Jiang H(1), Yin Y(1), Wu CR(2), Liu Y(1), Guo F(1), Li M(3), Ma L(1)(4). Author information: (1)School of Public Health, Xi'an Jiaotong University Health

11.
🧪 RCT
Effects of Randomized Multivitamin Supplementation on Carotenoids and α-Tocopherol in the COcoa Supplement and Multivitamin Outcomes Study.
Journal of the Academy of Nutrition and Dietetics 2026 PMID:41587736

11. J Acad Nutr Diet. 2026 May;126(5):156299. doi: 10.1016/j.jand.2026.156299. Epub 2026 Jan 24. Effects of Randomized Multivitamin Supplementation on Carotenoids and α-Tocopherol in the COcoa Supplement and Multivitamin Outcomes Study. Christopher CN(1), Erdman JW Jr(2), Kim E(3), Black M(2), R

12.
🧪 RCT
Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled trial.
The American journal of clinical nutrition 2025 PMID:40876538

12. Am J Clin Nutr. 2025 Nov;122(5):1289-1297. doi: 10.1016/j.ajcnut.2025.08.012. Epub 2025 Aug 27. Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled tri

13.
🧪 RCT
Enhanced Oral Bioavailability of Lutein and Zeaxanthin via a Self-Emulsifying Delivery System: A Randomized, Double-Blind Cross-Over Study.
Journal of medicinal food 2025 PMID:40601523

13. J Med Food. 2025 Aug;28(8):824-832. doi: 10.1089/jmf.2025.k.0060. Epub 2025 Jul 2. Enhanced Oral Bioavailability of Lutein and Zeaxanthin via a Self-Emulsifying Delivery System: A Randomized, Double-Blind Cross-Over Study. Choe BS(1), C A(2), Mk P(3), Kim J(4), Baek KS(4), Park YK(1). Autho

14.
📄 연구
Neuroprotective nutrients in pregnancy and infant brain function.
Clinical nutrition ESPEN 2025 PMID:40412614

14. Clin Nutr ESPEN. 2025 Aug;68:417-422. doi: 10.1016/j.clnesp.2025.05.030. Epub 2025 May 22. Neuroprotective nutrients in pregnancy and infant brain function. Christifano DN(1), Liao K(2), Mathis NB(3), Carlson SE(3), Colombo J(4), Chollet-Hinton L(5), Gustafson KM(2). Author information: (1)

15.
🧪 RCT
Effect of Dietary Supplementation with Lutein, Zeaxanthin, and Elderberries on Dry Eye Disease (DED) and Immunity: A Randomized Controlled Trial.
Nutrients 2024 PMID:39770987

15. Nutrients. 2024 Dec 18;16(24):4366. doi: 10.3390/nu16244366. Effect of Dietary Supplementation with Lutein, Zeaxanthin, and Elderberries on Dry Eye Disease (DED) and Immunity: A Randomized Controlled Trial. Goh KM(1)(2), Tan ESS(3), Lim CSY(4), Tan PY(5), Biswas S(6), Lew LA(2)(7), Tan CK(3)

16.
🧪 RCT
Beneficial Effects of Micronutrient Supplementation in Restoring the Altered Microbiota and Gut-Retina Axis in Patients with Neovascular Age-Related Macular Degeneration-A Randomized Clinical Trial.
Nutrients 2024 PMID:39599758

46. Nutrients. 2024 Nov 20;16(22):3971. doi: 10.3390/nu16223971. Beneficial Effects of Micronutrient Supplementation in Restoring the Altered Microbiota and Gut-Retina Axis in Patients with Neovascular Age-Related Macular Degeneration-A Randomized Clinical Trial. Baldi S(1), Pagliai G(1), Di Glo

17.
🧪 RCT
Pistachio Consumption Increases Macular Pigment Optical Density in Healthy Adults: A Randomized Controlled Trial.
The Journal of nutrition 2025 PMID:39426460

48. J Nutr. 2025 Jan;155(1):168-174. doi: 10.1016/j.tjnut.2024.10.022. Epub 2024 Oct 18. Pistachio Consumption Increases Macular Pigment Optical Density in Healthy Adults: A Randomized Controlled Trial. Scott TM(1), Ogunbodede O(2), McKay DL(3), Johnson EJ(3). Author information: (1)The Friedma

18.
📄 연구
Oral Antioxidant and Lutein/Zeaxanthin Supplements Slow Geographic Atrophy Progression to the Fovea in Age-Related Macular Degeneration.
Ophthalmology 2025 PMID:39025435

34. Ophthalmology. 2025 Jan;132(1):14-29. doi: 10.1016/j.ophtha.2024.07.014. Epub 2024 Jul 16. Oral Antioxidant and Lutein/Zeaxanthin Supplements Slow Geographic Atrophy Progression to the Fovea in Age-Related Macular Degeneration. Keenan TDL(1), Agrón E(2), Keane PA(3), Domalpally A(4), Chew EY

19.
📄 연구
Lutein, zeaxanthin, and meso-zeaxanthin supplementation attenuates inflammatory cytokines and markers of oxidative cardiovascular processes in humans.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2024 PMID:38890092

43. Nutr Metab Cardiovasc Dis. 2024 Aug;34(8):1976-1983. doi: 10.1016/j.numecd.2024.05.009. Epub 2024 May 14. Lutein, zeaxanthin, and meso-zeaxanthin supplementation attenuates inflammatory cytokines and markers of oxidative cardiovascular processes in humans. Stringham NT(1), Green M(2), Roche

20.
🧪 RCT
Bioavailability of Lutein from Marigold Flowers (Free vs. Ester Forms): A Randomised Cross-Over Study to Assess Serum Response and Visual Contrast Threshold in Adults.
Nutrients 2024 PMID:38794653

19. Nutrients. 2024 May 8;16(10):1415. doi: 10.3390/nu16101415. Bioavailability of Lutein from Marigold Flowers (Free vs. Ester Forms): A Randomised Cross-Over Study to Assess Serum Response and Visual Contrast Threshold in Adults. Olmedilla-Alonso B(1), Granado-Lorencio F(2), Castro-Feito J(3),

21.
📄 연구
Synergistic Action of Membrane-Bound and Water-Soluble Antioxidants in Neuroprotection.
Molecules (Basel, Switzerland) 2021 PMID:34500818

35. Molecules. 2021 Sep 4;26(17):5385. doi: 10.3390/molecules26175385. Synergistic Action of Membrane-Bound and Water-Soluble Antioxidants in Neuroprotection. Polutchko SK(1), Glime GNE(1), Demmig-Adams B(1). Author information: (1)Department of Ecology and Evolutionary Biology, University of Co

22.
📄 연구
Cytoprotective effects of carotenoids-rich extract from Lycium barbarum L. on the beauvericin-induced cytotoxicity on Caco-2 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 PMID:31473340

36. Food Chem Toxicol. 2019 Nov;133:110798. doi: 10.1016/j.fct.2019.110798. Epub 2019 Aug 29. Cytoprotective effects of carotenoids-rich extract from Lycium barbarum L. on the beauvericin-induced cytotoxicity on Caco-2 cells. Juan-García A(1), Montesano D(2), Mañes J(3), Juan C(3). Author infor

23.
📄 연구
In Vitro Inhibition of Human UDP-Glucuronosyl-Transferase (UGT) Isoforms by Astaxanthin, β-Cryptoxanthin, Canthaxanthin, Lutein, and Zeaxanthin: Prediction of in Vivo Dietary Supplement-Drug Interactions.
Molecules (Basel, Switzerland) 2016 PMID:27529203

40. Molecules. 2016 Aug 12;21(8):1052. doi: 10.3390/molecules21081052. In Vitro Inhibition of Human UDP-Glucuronosyl-Transferase (UGT) Isoforms by Astaxanthin, β-Cryptoxanthin, Canthaxanthin, Lutein, and Zeaxanthin: Prediction of in Vivo Dietary Supplement-Drug Interactions. Zheng YF(1), Min JS(

24.
📄 연구
Effect of dietary α-tocopherol on the bioavailability of lutein in laying hen.
Journal of animal physiology and animal nutrition 2016 PMID:27080067

5. J Anim Physiol Anim Nutr (Berl). 2016 Oct;100(5):868-75. doi: 10.1111/jpn.12464. Epub 2016 Apr 14. Effect of dietary α-tocopherol on the bioavailability of lutein in laying hen. Islam KM(1)(2), Khalil M(3), Männer K(4), Raila J(3), Rawel H(3), Zentek J(4), Schweigert FJ(3). Author informatio

25.
📄 연구
Inhibitory effects of astaxanthin, β-cryptoxanthin, canthaxanthin, lutein, and zeaxanthin on cytochrome P450 enzyme activities.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 PMID:23669408

33. Food Chem Toxicol. 2013 Sep;59:78-85. doi: 10.1016/j.fct.2013.04.053. Epub 2013 May 11. Inhibitory effects of astaxanthin, β-cryptoxanthin, canthaxanthin, lutein, and zeaxanthin on cytochrome P450 enzyme activities. Zheng YF(1), Bae SH, Kwon MJ, Park JB, Choi HD, Shin WG, Bae SK. Author inf

26.
📄 연구
Structural elucidation of possible lutein oxidation products mediated through peroxyl radical inducer 2,2'-Azobis (2-methylpropionamidine) dihydrochloride: antioxidant and cytotoxic influence of oxidized lutein in HeLa cells.
Chemico-biological interactions 2013 PMID:23518229

23. Chem Biol Interact. 2013 Apr 25;203(2):448-55. doi: 10.1016/j.cbi.2013.03.006. Epub 2013 Mar 18. Structural elucidation of possible lutein oxidation products mediated through peroxyl radical inducer 2,2'-Azobis (2-methylpropionamidine) dihydrochloride: antioxidant and cytotoxic influence of

27.
📄 연구
[Dietary supplements--evaluation of patient inquiries at a drug information service].
Deutsche medizinische Wochenschrift (1946) 2012 PMID:22511278

20. Dtsch Med Wochenschr. 2012 Apr;137(17):881-6. doi: 10.1055/s-0031-1299039. Epub 2012 Apr 17. [Dietary supplements--evaluation of patient inquiries at a drug information service]. [Article in German] Goltz L(1), Schröder J, Kirch W. Author information: (1)Arzneimittelberatungsdienst der Una

28.
📄 연구
Resveratrol protects human retinal pigment epithelial cells from acrolein-induced damage.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2010 PMID:20565308

26. J Ocul Pharmacol Ther. 2010 Jun;26(3):231-6. doi: 10.1089/jop.2009.0137. Resveratrol protects human retinal pigment epithelial cells from acrolein-induced damage. Sheu SJ(1), Liu NC, Chen JL. Author information: (1)Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung

29.
📄 연구
Increase in nutritionally important sweet corn kernel carotenoids following Mesotrione and atrazine applications.
Journal of agricultural and food chemistry 2009 PMID:19537793

17. J Agric Food Chem. 2009 Jul 22;57(14):6362-8. doi: 10.1021/jf9013313. Increase in nutritionally important sweet corn kernel carotenoids following Mesotrione and atrazine applications. Kopsell DA(1), Armel GR, Mueller TC, Sams CE, Deyton DE, McElroy JS, Kopsell DE. Author information: (1)Plan

30.
📄 연구
Bioaccessibility of pro-vitamin A carotenoids is minimally affected by non pro-vitamin a xanthophylls in maize (Zea mays sp.).
Journal of agricultural and food chemistry 2008 PMID:18991453

9. J Agric Food Chem. 2008 Dec 10;56(23):11441-6. doi: 10.1021/jf802430u. Bioaccessibility of pro-vitamin A carotenoids is minimally affected by non pro-vitamin a xanthophylls in maize (Zea mays sp.). Thakkar SK(1), Failla ML. Author information: (1)The Ohio State University, Columbus, 43210, US

🔗 같은 분류의 보충제

⚠️ 면책 고지

이 정보는 일반 교육 목적이며 의료 진단/처방을 대체하지 않습니다.