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커큐민 (파이토솜)

Curcumin (Phytosome)

📑 PubMed 30편 🛡️ 항산화 🗓️ 최신 2026
🔬 메타분석 2 📋 체계적 리뷰 1 🧪 RCT 5

📖 핵심 요약

📖 30편 · 15분 읽기

커큐민 (파이토솜)은(는) 항산화 계열 보충제입니다. 주로 간 건강, 수면 분야에서 연구되었으며, PubMed에 30편의 관련 논문이 있습니다.

🔍 연구 분야별 근거

간 건강 논문 10편
수면 논문 2편

* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)

📚 관련 논문 (30편) · 📊 정량 근거 1건

1.
🔬 메타분석
Improving quercetin bioavailability: A systematic review and meta-analysis of human intervention studies.
Food chemistry 2025 PMID:40037045

1. Food Chem. 2025 Jun 15;477:143630. doi: 10.1016/j.foodchem.2025.143630. Epub 2025 Feb 26. Improving quercetin bioavailability: A systematic review and meta-analysis of human intervention studies. Liu L(1), Barber E(1), Kellow NJ(2), Williamson G(3). Author information: (1)Department of Nutri

2.
🔬 메타분석
Quercetin for the treatment of COVID-19 patients: A systematic review and meta-analysis.
Reviews in medical virology 2023 PMID:36779438
📊 OR 0.31 (95% CI 0.1–0.62) · n=19

2. Rev Med Virol. 2023 Mar;33(2):e2427. doi: 10.1002/rmv.2427. Epub 2023 Feb 13. Quercetin for the treatment of COVID-19 patients: A systematic review and meta-analysis. Cheema HA(1), Sohail A(2), Fatima A(2), Shahid A(1), Shahzil M(1)(3), Ur Rehman ME(4), Awan RU(5), Chinnam S(6)(7), Nashwan AJ

3.
📋 체계적 리뷰
Trends in advanced oral drug delivery system for curcumin: A systematic review.
Journal of controlled release : official journal of the Controlled Release Society 2022 PMID:35654170

3. J Control Release. 2022 Aug;348:335-345. doi: 10.1016/j.jconrel.2022.05.048. Epub 2022 Jun 9. Trends in advanced oral drug delivery system for curcumin: A systematic review. Pan-On S(1), Dilokthornsakul P(2), Tiyaboonchai W(3). Author information: (1)Faculty of Pharmaceutical Sciences, Naresu

4.
🧪 RCT
Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery.
Scientific reports 2025 PMID:39929877

4. Sci Rep. 2025 Feb 10;15(1):4899. doi: 10.1038/s41598-025-86651-2. Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery. Sgaramella LI(1), Pasculli A(1), Moschetta M(2)(3), Puntillo F(2)(3), Dicillo P(4), Clemente L(1), Maruccia M(1)(2), Mastropasqua MG

5.
📄 연구
Effects of Melissa officinalis Phytosome on Sleep Quality: Results of a Prospective, Double-Blind, Placebo-Controlled, and Cross-Over Study.
Nutrients 2024 PMID:39683592

5. Nutrients. 2024 Dec 4;16(23):4199. doi: 10.3390/nu16234199. Effects of Melissa officinalis Phytosome on Sleep Quality: Results of a Prospective, Double-Blind, Placebo-Controlled, and Cross-Over Study. Di Pierro F(1)(2)(3), Sisti D(4), Rocchi M(4), Belli A(4), Bertuccioli A(2)(4), Cazzaniga M(

6.
📄 연구
Supplementation with Highly Standardized Cranberry Extract Phytosome Achieved the Modulation of Urinary Tract Infection Episodes in Diabetic Postmenopausal Women Taking SGLT-2 Inhibitors: A RCT Study.
Nutrients 2024 PMID:38999860

6. Nutrients. 2024 Jul 2;16(13):2113. doi: 10.3390/nu16132113. Supplementation with Highly Standardized Cranberry Extract Phytosome Achieved the Modulation of Urinary Tract Infection Episodes in Diabetic Postmenopausal Women Taking SGLT-2 Inhibitors: A RCT Study. Rondanelli M(1), Mansueto F(2),

7.
📄 연구
Two-month period of 500 mg lecithin-based delivery form of quercetin daily dietary supplementation counterbalances chronic fatigue symptoms: A double-blind placebo controlled clinical trial.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 PMID:37716119

7. Biomed Pharmacother. 2023 Nov;167:115453. doi: 10.1016/j.biopha.2023.115453. Epub 2023 Sep 15. Two-month period of 500 mg lecithin-based delivery form of quercetin daily dietary supplementation counterbalances chronic fatigue symptoms: A double-blind placebo controlled clinical trial. Rondan

8.
📄 연구
A 60-Day Green Tea Extract Supplementation Counteracts the Dysfunction of Adipose Tissue in Overweight Post-Menopausal and Class I Obese Women.
Nutrients 2022 PMID:36558368

8. Nutrients. 2022 Dec 7;14(24):5209. doi: 10.3390/nu14245209. A 60-Day Green Tea Extract Supplementation Counteracts the Dysfunction of Adipose Tissue in Overweight Post-Menopausal and Class I Obese Women. Rondanelli M(1)(2), Gasparri C(3), Perna S(4), Petrangolini G(5), Allegrini P(5), Fazia T

9.
🧪 RCT
Effects of repeated oral intake of a quercetin-containing supplement on allergic reaction: a randomized, placebo-controlled, double-blind parallel-group study.
European review for medical and pharmacological sciences 2022 PMID:35776034

9. Eur Rev Med Pharmacol Sci. 2022 Jun;26(12):4331-4345. doi: 10.26355/eurrev_202206_29072. Effects of repeated oral intake of a quercetin-containing supplement on allergic reaction: a randomized, placebo-controlled, double-blind parallel-group study. Yamada S(1), Shirai M, Inaba Y, Takara T. A

10.
📄 연구
Effect of Dietary Supplementation with Eufortyn(®) Colesterolo Plus on Serum Lipids, Endothelial Reactivity, Indexes of Non-Alcoholic Fatty Liver Disease and Systemic Inflammation in Healthy Subjects with Polygenic Hypercholesterolemia: The ANEMONE Study.
Nutrients 2022 PMID:35631240

10. Nutrients. 2022 May 18;14(10):2099. doi: 10.3390/nu14102099. Effect of Dietary Supplementation with Eufortyn(®) Colesterolo Plus on Serum Lipids, Endothelial Reactivity, Indexes of Non-Alcoholic Fatty Liver Disease and Systemic Inflammation in Healthy Subjects with Polygenic Hypercholesterole

11.
📄 연구
Positive Effects of a Lecithin-Based Delivery Form of Boswellia serrata Extract in Acute Diarrhea of Adult Subjects.
Nutrients 2022 PMID:35565826

11. Nutrients. 2022 Apr 29;14(9):1858. doi: 10.3390/nu14091858. Positive Effects of a Lecithin-Based Delivery Form of Boswellia serrata Extract in Acute Diarrhea of Adult Subjects. Giacosa A(1), Riva A(2), Petrangolini G(2), Allegrini P(2), Fazia T(3), Bernardinelli L(3), Peroni G(4), Rondanelli

12.
🧪 RCT
Noninvasive instrumental evaluation of coenzyme Q(10) phytosome on endothelial reactivity in healthy nonsmoking young volunteers: A double-blind, randomized, placebo-controlled crossover clinical trial.
BioFactors (Oxford, England) 2022 PMID:35342994

12. Biofactors. 2022 Sep;48(5):1160-1165. doi: 10.1002/biof.1839. Epub 2022 Mar 28. Noninvasive instrumental evaluation of coenzyme Q(10) phytosome on endothelial reactivity in healthy nonsmoking young volunteers: A double-blind, randomized, placebo-controlled crossover clinical trial. Cicero AF

13.
📄 연구
Beneficial Effects on Abdominal Bloating with an Innovative Food-Grade Formulation of Curcuma longa and Boswellia serrata Extracts in Subjects with Irritable Bowel Syndrome and Small Bowel Dysbiosis.
Nutrients 2022 PMID:35276778

13. Nutrients. 2022 Jan 18;14(3):416. doi: 10.3390/nu14030416. Beneficial Effects on Abdominal Bloating with an Innovative Food-Grade Formulation of Curcuma longa and Boswellia serrata Extracts in Subjects with Irritable Bowel Syndrome and Small Bowel Dysbiosis. Giacosa A(1), Riva A(2), Petrango

14.
📄 연구
A Lecithin-Based Delivery Form of Quercetin Promotes Stress Resistance and Longevity in Caenorhabditis elegans.
Pharmaceuticals (Basel, Switzerland) 2026 PMID:42075782

14. Pharmaceuticals (Basel). 2026 Mar 24;19(4):525. doi: 10.3390/ph19040525. A Lecithin-Based Delivery Form of Quercetin Promotes Stress Resistance and Longevity in Caenorhabditis elegans. Romeo M(1), Barzago MM(1), Fracasso C(1), Nettis M(1), Riva A(2), Gobbi M(1), Tongiani S(2), Diomede L(1).

15.
📄 연구
Evaluation of an oral Beta-caryophyllene Indena Phytosome(®) for the treatment of pain and inflammation in interstitial cystitis.
Clinical hemorheology and microcirculation 2026 PMID:42029705

15. Clin Hemorheol Microcirc. 2026 Apr 24:13860291261442989. doi: 10.1177/13860291261442989. Online ahead of print. Evaluation of an oral Beta-caryophyllene Indena Phytosome(®) for the treatment of pain and inflammation in interstitial cystitis. White H(1), Dickson K(2), Scott C(1), Agonh DN(3),

16.
📄 연구
Terpenoid Phytosomes as Advanced Delivery Systems: Molecular Interactions, Pharmacological Potential, and Scalable Manufacturing Approaches.
International journal of molecular sciences 2026 PMID:41898727

5. Int J Mol Sci. 2026 Mar 22;27(6):2868. doi: 10.3390/ijms27062868. Terpenoid Phytosomes as Advanced Delivery Systems: Molecular Interactions, Pharmacological Potential, and Scalable Manufacturing Approaches. Sergazy S(1), Aliakpar S(1), Adekenova G(1), Itzhanova K(2), Taglialatela-Scafati O(3)

17.
📄 연구
Development and Evaluation of a Baicalin-Loaded Phytosomal Transdermal Patch for Type 2 Diabetes Mellitus.
Current drug metabolism 2026 PMID:41879453

19. Curr Drug Metab. 2026 Mar 23. doi: 10.2174/0113892002437368260113092840. Online ahead of print. Development and Evaluation of a Baicalin-Loaded Phytosomal Transdermal Patch for Type 2 Diabetes Mellitus. Singhal P(1), Mazumder R(1), Rani A(1), Debnath A(1). Author information: (1)Noida Insti

18.
📄 연구
Neuroprotective effects of Premna integrifolia nano-phytosomes in haloperidol-induced Parkinson's rat model: A computational-guided Olivil nanoformulation delivery approach.
Metabolic brain disease 2026 PMID:41874857

13. Metab Brain Dis. 2026 Mar 24;41(1):66. doi: 10.1007/s11011-026-01821-z. Neuroprotective effects of Premna integrifolia nano-phytosomes in haloperidol-induced Parkinson's rat model: A computational-guided Olivil nanoformulation delivery approach. Biradar PR(1), Naik S(2), Dwivedi PSR(3), Mall

19.
📄 연구
The Role of Phytosomes in Enhancing the Bioavailability and Efficacy of Herbal Phytoconstituents with Anxiolytic Potential - A Comprehensive Review.
Current pharmaceutical design 2026 PMID:41832690

42. Curr Pharm Des. 2026 Mar 12. doi: 10.2174/0113816128409746251128052335. Online ahead of print. The Role of Phytosomes in Enhancing the Bioavailability and Efficacy of Herbal Phytoconstituents with Anxiolytic Potential - A Comprehensive Review. Mahima(1), Mazumder A(1), Pentela B(1). Author

20.
📄 연구
Melissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress.
Food & nutrition research 2026 PMID:41777239

46. Food Nutr Res. 2026 Jan 31;70. doi: 10.29219/fnr.v70.13729. eCollection 2026. Melissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress. Rondanelli M(1)(2), Mazzola G(2), Barrile GC(2), Misiano P(3), Perna S(4)

21.
📄 연구
Phospholipid-Based Delivery System Optimizes the Solubility and Systemic Exposure of Palmitoylethanolamide and Supports Clinical Benefits in Chronic Neuropathic Low Back Pain.
Biomedicines 2026 PMID:41751279

45. Biomedicines. 2026 Feb 6;14(2):380. doi: 10.3390/biomedicines14020380. Phospholipid-Based Delivery System Optimizes the Solubility and Systemic Exposure of Palmitoylethanolamide and Supports Clinical Benefits in Chronic Neuropathic Low Back Pain. Khan A(1)(2), Rabbani F(3), Kanwal A(3), Shaf

22.
📄 연구
Correction to "Antimetabolic Syndrome Effect of Phytosome Containing the Combined Extracts of Mulberry and Ginger in an Animal Model of Metabolic Syndrome".
Oxidative medicine and cellular longevity 2025 PMID:41322022

20. Oxid Med Cell Longev. 2025 Nov 21;2025:9871678. doi: 10.1155/omcl/9871678. eCollection 2025. Correction to "Antimetabolic Syndrome Effect of Phytosome Containing the Combined Extracts of Mulberry and Ginger in an Animal Model of Metabolic Syndrome". [No authors listed] Erratum for Oxid

23.
📄 연구
Nanoparticle-Based Delivery of Resveratrol Suppresses Ehrlich Ascites Carcinoma and Protects Testicular Function via Antioxidant, Anti-Angiogenic, Anti-Inflammatory, and Pro-Apoptotic Mechanisms.
Biomolecules 2025 PMID:41301523

43. Biomolecules. 2025 Nov 15;15(11):1605. doi: 10.3390/biom15111605. Nanoparticle-Based Delivery of Resveratrol Suppresses Ehrlich Ascites Carcinoma and Protects Testicular Function via Antioxidant, Anti-Angiogenic, Anti-Inflammatory, and Pro-Apoptotic Mechanisms. Alfawaz M(1), Elmorsy EM(2)(3)

24.
📄 연구
Effect of Nutraceutical Supplementation and Mediterranean Hypocaloric Diet on Calculated Steatosis Indices and Inflammation: Clinical and In Vitro Evidences.
Molecular nutrition & food research 2025 PMID:40913543

17. Mol Nutr Food Res. 2025 Nov;69(21):e70207. doi: 10.1002/mnfr.70207. Epub 2025 Sep 6. Effect of Nutraceutical Supplementation and Mediterranean Hypocaloric Diet on Calculated Steatosis Indices and Inflammation: Clinical and In Vitro Evidences. Di Lorenzo M(1), Pipicelli L(1), Aurino L(1), Soz

25.
📄 연구
Enhancing the bioavailability of Phyllanthus amarus: implications for traditional and modern medicine in Africa.
Annals of medicine and surgery (2012) 2025 PMID:40901185

32. Ann Med Surg (Lond). 2025 Jun 21;87(9):5631-5636. doi: 10.1097/MS9.0000000000003514. eCollection 2025 Sep. Enhancing the bioavailability of Phyllanthus amarus: implications for traditional and modern medicine in Africa. Anyiam AF(1)(2), Muhibi MA(1), Arinze-Anyiam OC(2), Obeagu EI(3). Autho

26.
📄 연구
Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies.
Frontiers in nutrition 2025 PMID:39990611

12. Front Nutr. 2025 Feb 7;12:1519459. doi: 10.3389/fnut.2025.1519459. eCollection 2025. Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies. Di Pierro F(1)(2)(3), Rabbani F(4), Tareen M(5), Nigar R(6), Khan A(7),

27.
📄 연구
Positive Outcomes of Supplementation with Lecithin-Based Delivery Formulation of Curcuma longa and Boswellia serrata in IBS Subjects with Small Bowel Dysbiosis.
Life (Basel, Switzerland) 2024 PMID:39598208

38. Life (Basel). 2024 Nov 1;14(11):1410. doi: 10.3390/life14111410. Positive Outcomes of Supplementation with Lecithin-Based Delivery Formulation of Curcuma longa and Boswellia serrata in IBS Subjects with Small Bowel Dysbiosis. Giacosa A(1), Barrile GC(2), Perna S(3), Rondanelli M(2). Author i

28.
🧪 RCT
Effect of Coenzyme Q(10) on Physical Performance in Older Adults with Statin-Associated Asthenia: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial.
Journal of clinical medicine 2024 PMID:38999304

32. J Clin Med. 2024 Jun 26;13(13):3741. doi: 10.3390/jcm13133741. Effect of Coenzyme Q(10) on Physical Performance in Older Adults with Statin-Associated Asthenia: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial. Fogacci F(1), Giovannini M(1), Tocci G(2), Imbalzano E(3), Borghi C(

29.
📄 연구
An in vitro analysis of an innovative standardized phospholipid carrier-based Melissa officinalis L. extract as a potential neuromodulator for emotional distress and related conditions.
Frontiers in molecular biosciences 2024 PMID:38545418

50. Front Mol Biosci. 2024 Mar 13;11:1359177. doi: 10.3389/fmolb.2024.1359177. eCollection 2024. An in vitro analysis of an innovative standardized phospholipid carrier-based Melissa officinalis L. extract as a potential neuromodulator for emotional distress and related conditions. Kara M(1), S

30.
🧪 RCT
Effect of Berberine Phytosome on reproductive, dermatologic, and metabolic characteristics in women with polycystic ovary syndrome: a controlled, randomized, multi-centric, open-label clinical trial.
Frontiers in pharmacology 2023 PMID:38074133

43. Front Pharmacol. 2023 Nov 21;14:1269605. doi: 10.3389/fphar.2023.1269605. eCollection 2023. Effect of Berberine Phytosome on reproductive, dermatologic, and metabolic characteristics in women with polycystic ovary syndrome: a controlled, randomized, multi-centric, open-label clinical trial.

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