미오이노시톨 (PCOS)

The effect of nutraceutical interventions on reproductive health outcomes in women with polycystic ovary syndrome: A systematic review and meta-analysis.

1. Diabetes Obes Metab. 2026 Feb;28(2):1213-1233. doi: 10.1111/dom.70307. Epub 2025 Nov 24. The effect of nutraceutical interventions on reproductive health outcomes in women with polycystic ovary syndrome: A systematic review and meta-analysis. Çelik ZM(1), Kurnaz D(2), Özcan A(3), Keskin E(3),

The effectiveness of nutritional supplements in improving polycystic ovary syndrome in women: a systematic review and network meta-analysis.

2. Reprod Biol Endocrinol. 2025 Jul 3;23(1):94. doi: 10.1186/s12958-025-01409-9. The effectiveness of nutritional supplements in improving polycystic ovary syndrome in women: a systematic review and network meta-analysis. Zhao G(#)(1)(2), Fan Y(#)(2), Li R(#)(2), Huang Y(2), Li W(2), Zhao Y(3), Z

Effect of myo-inositol supplementation in mixed ovarian response IVF cohort: a systematic review and meta-analysis.

3. Front Endocrinol (Lausanne). 2025 Mar 21;16:1520362. doi: 10.3389/fendo.2025.1520362. eCollection 2025. Effect of myo-inositol supplementation in mixed ovarian response IVF cohort: a systematic review and meta-analysis. Zhang J(1), Zhang H(1), Zhou W(1), Jiang M(1), Lin X(1). Author informat

Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.

4. PeerJ. 2023 Nov 13;11:e16410. doi: 10.7717/peerj.16410. eCollection 2023. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis. Hu X(1), Wang W(1), Su X(1), Peng H(1), Tan Z(

Efficacy of Myo-inositol on Anthropometric, Metabolic, and Endocrine Outcomes in PCOS Patients: a Meta-analysis of Randomized Controlled Trial.

5. Reprod Sci. 2022 Aug;29(8):2282-2298. doi: 10.1007/s43032-022-00933-y. Epub 2022 Apr 27. Efficacy of Myo-inositol on Anthropometric, Metabolic, and Endocrine Outcomes in PCOS Patients: a Meta-analysis of Randomized Controlled Trial. Jethaliya H(1), Gajjar N(1), Patel V(1), Deshpande S(1), Pat

Short period-administration of myo-inositol and metformin on hormonal and glycolipid profiles in patients with polycystic ovary syndrome: a systematic review and updated meta-analysis of randomized controlled trials.

6. Eur Rev Med Pharmacol Sci. 2022 Mar;26(6):1792-1802. doi: 10.26355/eurrev_202203_28322. Short period-administration of myo-inositol and metformin on hormonal and glycolipid profiles in patients with polycystic ovary syndrome: a systematic review and updated meta-analysis of randomized control

The effectiveness of coenzyme Q10, vitamin E, inositols, and vitamin D in improving the endocrine and metabolic profiles in women with polycystic ovary syndrome: a network Meta-analysis.

7. Gynecol Endocrinol. 2021 Dec;37(12):1063-1071. doi: 10.1080/09513590.2021.1926975. Epub 2021 May 14. The effectiveness of coenzyme Q10, vitamin E, inositols, and vitamin D in improving the endocrine and metabolic profiles in women with polycystic ovary syndrome: a network Meta-analysis. Zhan

Short-term effects of metformin and myo-inositol in women with polycystic ovarian syndrome (PCOS): a meta-analysis of randomized clinical trials.

8. Gynecol Endocrinol. 2019 Mar;35(3):198-206. doi: 10.1080/09513590.2018.1540578. Epub 2019 Jan 7. Short-term effects of metformin and myo-inositol in women with polycystic ovarian syndrome (PCOS): a meta-analysis of randomized clinical trials. Facchinetti F(1), Orrù B(2), Grandi G(1), Unfer V(

Inositol for subfertile women with polycystic ovary syndrome.

9. Cochrane Database Syst Rev. 2018 Dec 20;12(12):CD012378. doi: 10.1002/14651858.CD012378.pub2. Inositol for subfertile women with polycystic ovary syndrome. Showell MG(1), Mackenzie-Proctor R, Jordan V, Hodgson R, Farquhar C. Author information: (1)Department of Obstetrics and Gynaecology, Uni

Myo-inositol supplementation reduces the amount of gonadotropins and length of ovarian stimulation in women undergoing IVF: a systematic review and meta-analysis of randomized controlled trials.

10. Arch Gynecol Obstet. 2018 Oct;298(4):675-684. doi: 10.1007/s00404-018-4861-y. Epub 2018 Aug 4. Myo-inositol supplementation reduces the amount of gonadotropins and length of ovarian stimulation in women undergoing IVF: a systematic review and meta-analysis of randomized controlled trials. L

Effects of Ziziphus jujuba, metformin, and myoinositol on pregnancy rates and metabolic parameters in infertile women with PCOS: a randomized controlled trial.

11. J Ovarian Res. 2026 Jan 30;19(1):51. doi: 10.1186/s13048-025-01867-0. Effects of Ziziphus jujuba, metformin, and myoinositol on pregnancy rates and metabolic parameters in infertile women with PCOS: a randomized controlled trial. Mashhadi F(1), Ghaebi NK(2), Rakhshandeh H(3), Khadem-Rezaiyan

Effect of Myo-Inositol Treatment on Serum Asprosin Levels of Pregnant Women: A Prospective Randomized Controlled Pilot Study.

12. J Pregnancy. 2025 Dec 28;2025:8816154. doi: 10.1155/jp/8816154. eCollection 2025. Effect of Myo-Inositol Treatment on Serum Asprosin Levels of Pregnant Women: A Prospective Randomized Controlled Pilot Study. Özay AC(1)(2), Özay ÖE(1), Edebal OH(3), Özay Y(4), Montanino Oliva M(2)(5), Dinico

Effect of Insulin Sensitizers on Glycemic and Lipid Profile in Patients with Polycystic Ovary Syndrome (PCOS).

13. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2025 Dec 6;46(3):51-62. doi: 10.2478/prilozi-2025-0022. Print 2025 Nov 1. Effect of Insulin Sensitizers on Glycemic and Lipid Profile in Patients with Polycystic Ovary Syndrome (PCOS). Stevchevska A(1), Milenkovic T(1). Author information: (1)Uni

Myo-inositol Supplementation to Prevent Pregnancy Complications in Polycystic Ovary Syndrome: A Randomized Clinical Trial.

14. JAMA. 2025 Oct 7;334(13):1151-1159. doi: 10.1001/jama.2025.13668. Myo-inositol Supplementation to Prevent Pregnancy Complications in Polycystic Ovary Syndrome: A Randomized Clinical Trial. van der Wel AWT(1)(2), Frank CMC(3), Bout-Rebel R(4), Duijnhoven RG(1)(5), van Bree BE(6), Valkenburg O

Effect of 40:1 myo-inositol/D-chiro-inositol treatment on serum asprosin levels in polycystic ovary syndrome: a prospective randomized pilot study.

15. Ginekol Pol. 2025;96(11):925-931. doi: 10.5603/gpl.103763. Epub 2025 Jul 16. Effect of 40:1 myo-inositol/D-chiro-inositol treatment on serum asprosin levels in polycystic ovary syndrome: a prospective randomized pilot study. Ozay OE(1), Ozay Y(2), Edebal O(3), Calcagno M(4), Ozay AC(5)(6). A

The ameliorative effect of myo-inositol on apoptosis-related genes expression in cumulus cells of women with polycystic ovary syndrome undergoing ICSI and its relationship with the quality of oocyte and embryo.

38. Naunyn Schmiedebergs Arch Pharmacol. 2025 Aug;398(8):10635-10644. doi: 10.1007/s00210-025-03952-z. Epub 2025 Feb 28. The ameliorative effect of myo-inositol on apoptosis-related genes expression in cumulus cells of women with polycystic ovary syndrome undergoing ICSI and its relationship wit

Comparative efficacy of combined myo-inositol and D-chiro inositol versus metformin across PCOS Phenotypes: enhancing ovarian function, ovulation, and stress response in a prospective clinical trial.

15. Naunyn Schmiedebergs Arch Pharmacol. 2025 Jul;398(7):8761-8772. doi: 10.1007/s00210-025-03813-9. Epub 2025 Jan 23. Comparative efficacy of combined myo-inositol and D-chiro inositol versus metformin across PCOS Phenotypes: enhancing ovarian function, ovulation, and stress response in a prosp

Improvement in biochemical manifestations of the serum and follicular fluid and ICSI outcomes in PCOS patients with myo-inositol administration: prospective randomized research.

44. Naunyn Schmiedebergs Arch Pharmacol. 2025 Jun;398(6):7187-7198. doi: 10.1007/s00210-024-03745-w. Epub 2024 Dec 24. Improvement in biochemical manifestations of the serum and follicular fluid and ICSI outcomes in PCOS patients with myo-inositol administration: prospective randomized research.

Effectiveness of dual combination therapy of acarbose plus metformin and acarbose plus myo-inositol in ameliorating the metabolic and endocrinologic complications of polycystic ovary syndrome - A randomized controlled trial.

43. Eur J Obstet Gynecol Reprod Biol. 2024 Sep;300:6-11. doi: 10.1016/j.ejogrb.2024.07.001. Epub 2024 Jul 3. Effectiveness of dual combination therapy of acarbose plus metformin and acarbose plus myo-inositol in ameliorating the metabolic and endocrinologic complications of polycystic ovary synd

Antimüllerian hormone level predicts ovulation in women with polycystic ovary syndrome treated with clomiphene and metformin.

48. Fertil Steril. 2024 Apr;121(4):660-668. doi: 10.1016/j.fertnstert.2023.12.031. Epub 2023 Dec 26. Antimüllerian hormone level predicts ovulation in women with polycystic ovary syndrome treated with clomiphene and metformin. Komorowski AS(1), Hughes L(2), Sarkar P(3), Aaby DA(4), Kumar A(5), K

Comparison of metformin plus myoinositol vs metformin alone in PCOS women undergoing ovulation induction cycles: randomized controlled trial.

5. Gynecol Endocrinol. 2019 Jun;35(6):511-514. doi: 10.1080/09513590.2018.1549656. Epub 2019 Jan 7. Comparison of metformin plus myoinositol vs metformin alone in PCOS women undergoing ovulation induction cycles: randomized controlled trial. Agrawal A(1), Mahey R(1), Kachhawa G(1), Khadgawat R(2

Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials.

27. Front Endocrinol (Lausanne). 2026 Feb 11;17:1741509. doi: 10.3389/fendo.2026.1741509. eCollection 2026. Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials. Duan M(1)(2), Yang M(1)(2), Li C(1)(2), Wu X(1)(2), Yin

The Role of Nutrient Supplements in Female Infertility: An Umbrella Review and Hierarchical Evidence Synthesis.

16. Nutrients. 2024 Dec 27;17(1):57. doi: 10.3390/nu17010057. The Role of Nutrient Supplements in Female Infertility: An Umbrella Review and Hierarchical Evidence Synthesis. Pandey C(1), Maunder A(1), Liu J(1), Vaddiparthi V(1), Costello MF(2), Bahri-Khomami M(3), Mousa A(3), Ee C(1). Author in

Comparative efficacy and safety of metformin, anti-obesity agents, and myoinositol in improving IVF/ICSI outcomes and reducing ovarian hyperstimulation syndrome in women with polycystic ovary syndrome: a systematic review and network meta-analysis.

28. J Ovarian Res. 2024 Dec 19;17(1):249. doi: 10.1186/s13048-024-01576-0. Comparative efficacy and safety of metformin, anti-obesity agents, and myoinositol in improving IVF/ICSI outcomes and reducing ovarian hyperstimulation syndrome in women with polycystic ovary syndrome: a systematic review

Comparison of metformin with inositol versus metformin alone in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.

50. Endocrine. 2025 Feb;87(2):389-399. doi: 10.1007/s12020-024-04052-3. Epub 2024 Sep 27. Comparison of metformin with inositol versus metformin alone in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Kelly FA(1), de Oliveira Macena

Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines.

35. J Clin Endocrinol Metab. 2024 May 17;109(6):1630-1655. doi: 10.1210/clinem/dgad762. Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines. Fitz V(1), Graca S(2), Mahalingaiah S(1), Liu J(3),

Myoinositol or D-chiro-inositol for PCOS symptoms in adolescents: a narrative review.

16. J Pediatr Endocrinol Metab. 2023 Dec 21;37(2):91-101. doi: 10.1515/jpem-2023-0458. Print 2024 Feb 26. Myoinositol or D-chiro-inositol for PCOS symptoms in adolescents: a narrative review. Sairally BZF(1), Dhillon-Smith RK(1), Jethwani G(1), Latthe P(1). Author information: (1)Birmingham Wom