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DHA (임신)

DHA (Pregnancy)

📑 PubMed 30편 ♀️ 여성 🗓️ 최신 2026
🔬 메타분석 9 📋 체계적 리뷰 1 🧪 RCT 4

📖 핵심 요약

📖 30편 · 15분 읽기

DHA (임신)은(는) 여성 계열 보충제입니다. 주로 간 건강, 우울 개선 분야에서 연구되었으며, PubMed에 30편의 관련 논문이 있습니다.

🔍 연구 분야별 근거

간 건강 논문 1편
우울 개선 논문 1편

* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)

📊 효과 크기 분포 (Forest plot)

각 연구의 효과 추정치와 95% 신뢰구간. 개별 연구를 통합(pooling)하지 않고 그대로 표시합니다.

357723872.46 (1.28–4.73)353488290.84 (0.74–0.96)329429380.92 (0.85–1.01)304807730.58 (0.44–0.77)384087250.130.215RR (favours ← / →)

📚 관련 논문 (30편) · 📊 정량 근거 6건

1.
🔬 메타분석
Docosahexaenoic Acid and Pregnancy: A Systematic Review and Meta-Analysis of the Association with Improved Maternal and Fetal Health.
Nutrition research (New York, N.Y.) 2024 PMID:39067112

1. Nutr Res. 2024 Aug;128:82-93. doi: 10.1016/j.nutres.2024.06.008. Epub 2024 Jul 3. Docosahexaenoic Acid and Pregnancy: A Systematic Review and Meta-Analysis of the Association with Improved Maternal and Fetal Health. Bilgundi K(1), Viswanatha GL(1), Purushottam KM(2), John J(1), Kamath AP(1),

2.
🔬 메타분석
Interventions for the Prevention of Preterm Premature Rupture of Membranes: A Systematic Review and Meta-Analysis.
Fetal diagnosis and therapy 2022 PMID:35772387
📊 RR 2.46 (95% CI 1.28–4.73) · n=98

2. Fetal Diagn Ther. 2022;49(5-6):273-278. doi: 10.1159/000525655. Epub 2022 Jun 30. Interventions for the Prevention of Preterm Premature Rupture of Membranes: A Systematic Review and Meta-Analysis. El-Achi V(1), Aggarwal S(2), Hyett J(3)(4). Author information: (1)Department of Maternal and F

3.
🔬 메타분석
Impact of n-3 polyunsaturated fatty acid intake in pregnancy on maternal health and birth outcomes: systematic review and meta-analysis from randomized controlled trails.
Archives of gynecology and obstetrics 2023 PMID:35348829
📊 RR 0.84 (95% CI 0.74–0.96) · n=919

3. Arch Gynecol Obstet. 2023 Jan;307(1):249-262. doi: 10.1007/s00404-022-06533-0. Epub 2022 Mar 28. Impact of n-3 polyunsaturated fatty acid intake in pregnancy on maternal health and birth outcomes: systematic review and meta-analysis from randomized controlled trails. Abdelrahman MA(1), Osama

4.
🔬 메타분석
Omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation for prevention and treatment of perinatal depression: a systematic review and meta-analysis of randomized-controlled trials.
Nordic journal of psychiatry 2021 PMID:33190574

4. Nord J Psychiatry. 2021 May;75(4):239-246. doi: 10.1080/08039488.2020.1843710. Epub 2020 Nov 15. Omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation for prevention and treatment of perinatal depression: a systematic review and meta-analysis of randomized-controlled trials. Suradom

5.
🔬 메타분석
Association between omega-3 fatty acid supplementation and lower risk of preterm delivery: a systematic review and meta-analysis.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PMID:32942938
📊 RR 0.92 (95% CI 0.85–1.01) · n=20124

5. J Matern Fetal Neonatal Med. 2022 Jun;35(12):2294-2303. doi: 10.1080/14767058.2020.1785423. Epub 2020 Sep 17. Association between omega-3 fatty acid supplementation and lower risk of preterm delivery: a systematic review and meta-analysis. Sun L(1), Li Y(1), Xie W(1), Xue X(1). Author inform

6.
🔬 메타분석
Impact of omega-3 fatty acid DHA and EPA supplementation in pregnant or breast-feeding women on cognitive performance of children: systematic review and meta-analysis.
Nutrition reviews 2021 PMID:32918470

6. Nutr Rev. 2021 Apr 7;79(5):585-598. doi: 10.1093/nutrit/nuaa060. Impact of omega-3 fatty acid DHA and EPA supplementation in pregnant or breast-feeding women on cognitive performance of children: systematic review and meta-analysis. Lehner A(1), Staub K(1)(2), Aldakak L(1), Eppenberger P(1),

7.
🔬 메타분석
Efficacy of n-3 fatty acids supplementation on the prevention of pregnancy induced-hypertension or preeclampsia: A systematic review and meta-analysis.
Taiwanese journal of obstetrics & gynecology 2020 PMID:32039806

7. Taiwan J Obstet Gynecol. 2020 Jan;59(1):8-15. doi: 10.1016/j.tjog.2019.11.002. Efficacy of n-3 fatty acids supplementation on the prevention of pregnancy induced-hypertension or preeclampsia: A systematic review and meta-analysis. Bakouei F(1), Delavar MA(2), Mashayekh-Amiri S(3), Esmailzadeh

8.
🔬 메타분석
Influence of oral vitamin and mineral supplementation on male infertility: a meta-analysis and systematic review.
Reproductive biomedicine online 2019 PMID:31160241
📊 SMD 0.57

8. Reprod Biomed Online. 2019 Aug;39(2):269-279. doi: 10.1016/j.rbmo.2019.03.099. Epub 2019 Mar 16. Influence of oral vitamin and mineral supplementation on male infertility: a meta-analysis and systematic review. Buhling K(1), Schumacher A(2), Eulenburg CZ(3), Laakmann E(2). Author information

9.
📄 연구
Omega-3 fatty acid addition during pregnancy.
The Cochrane database of systematic reviews 2018 PMID:30480773
📊 RR 0.58 (95% CI 0.44–0.77) · n=927

9. Cochrane Database Syst Rev. 2018 Nov 15;11(11):CD003402. doi: 10.1002/14651858.CD003402.pub3. Omega-3 fatty acid addition during pregnancy. Middleton P(1), Gomersall JC, Gould JF, Shepherd E, Olsen SF, Makrides M. Author information: (1)Healthy Mothers, Babies and Children, South Australian H

10.
🔬 메타분석
The effectiveness of ω-3 polyunsaturated fatty acid interventions during pregnancy on obesity measures in the offspring: an up-to-date systematic review and meta-analysis.
European journal of nutrition 2019 PMID:30251019

10. Eur J Nutr. 2019 Oct;58(7):2597-2613. doi: 10.1007/s00394-018-1824-9. Epub 2018 Sep 24. The effectiveness of ω-3 polyunsaturated fatty acid interventions during pregnancy on obesity measures in the offspring: an up-to-date systematic review and meta-analysis. Vahdaninia M(1)(2), Mackenzie H

11.
🧪 RCT
Effect of high-docosahexaenoic acid omega-3 supplementation in low-risk pregnant women on maternal and neonatal health outcomes in Southeast Brazil: a randomized clinical trial.
Journal of tropical pediatrics 2026 PMID:41847904

11. J Trop Pediatr. 2026 Feb 9;72(2):fmag019. doi: 10.1093/tropej/fmag019. Effect of high-docosahexaenoic acid omega-3 supplementation in low-risk pregnant women on maternal and neonatal health outcomes in Southeast Brazil: a randomized clinical trial. de Sousa TM(1), Cotting CSO(2), Ferreira LA

12.
🧪 RCT
Docosahexaenoic acid supplementation in pregnancy and early lactation: Impacts on breast milk docosahexaenoic acid and Maternal-Infant gut microbiota - A randomized controlled trial.
Clinical nutrition (Edinburgh, Scotland) 2025 PMID:41045839

12. Clin Nutr. 2025 Nov;54:71-82. doi: 10.1016/j.clnu.2025.09.006. Epub 2025 Sep 23. Docosahexaenoic acid supplementation in pregnancy and early lactation: Impacts on breast milk docosahexaenoic acid and Maternal-Infant gut microbiota - A randomized controlled trial. He T(1), Zhang J(1), Zhao A(

13.
📄 연구
Effects of Prenatal DHA Dose on Infant Visual Attention.
Developmental psychobiology 2025 PMID:40791013

13. Dev Psychobiol. 2025 Sep;67(5):e70072. doi: 10.1002/dev.70072. Effects of Prenatal DHA Dose on Infant Visual Attention. Colombo J(1), Shaddy DJ(2), Mathis N(2), Christifano DN(2), Brown AR(3), Gajewski BJ(3), Carlson SE(2), Gustafson KM(4). Author information: (1)Department of Psychology and

14.
📄 연구
Neuroprotective nutrients in pregnancy and infant brain function.
Clinical nutrition ESPEN 2025 PMID:40412614

14. Clin Nutr ESPEN. 2025 Aug;68:417-422. doi: 10.1016/j.clnesp.2025.05.030. Epub 2025 May 22. Neuroprotective nutrients in pregnancy and infant brain function. Christifano DN(1), Liao K(2), Mathis NB(3), Carlson SE(3), Colombo J(4), Chollet-Hinton L(5), Gustafson KM(2). Author information: (1)

15.
📄 연구
Docosahexaenoic Acid Supplementation During Pregnancy and Lactation and Infant Morbidity: Findings from DHANI Trial.
Indian pediatrics 2025 PMID:40126831

15. Indian Pediatr. 2025 Mar;62(3):189-196. doi: 10.1007/s13312-025-00007-7. Epub 2025 Feb 28. Docosahexaenoic Acid Supplementation During Pregnancy and Lactation and Infant Morbidity: Findings from DHANI Trial. Khandelwal S(1), Kaur T(2), Kondal D(2), Patil K(3), Swamy MK(3), Prabhakaran D(2),

16.
🧪 RCT
Can prenatal conditions impact the effect of omega-3 on bronchopulmonary dysplasia in very preterm infants? A secondary analysis of a randomized controlled trial.
European journal of pediatrics 2025 PMID:40072608

42. Eur J Pediatr. 2025 Mar 12;184(4):243. doi: 10.1007/s00431-025-06053-4. Can prenatal conditions impact the effect of omega-3 on bronchopulmonary dysplasia in very preterm infants? A secondary analysis of a randomized controlled trial. Rais H(1), Pronovost E(1), Guillot M(1), Boutin A(1), Sim

17.
📄 연구
Maternal high-dose docosahexaenoic acid supplementation and neurodevelopment at 5 Years of preterm children.
Clinical nutrition ESPEN 2024 PMID:39396702

2. Clin Nutr ESPEN. 2024 Dec;64:253-262. doi: 10.1016/j.clnesp.2024.09.029. Epub 2024 Oct 11. Maternal high-dose docosahexaenoic acid supplementation and neurodevelopment at 5 Years of preterm children. Paquet SP(1), Pronovost E(2), Simonyan D(3), Caouette G(4), Matte-Gagné C(5), Olivier F(6),

18.
📄 연구
Growth patterns in infants born to women with pregestational overweight/obesity supplemented with docosahexaenoic acid during pregnancy.
Journal of pediatric gastroenterology and nutrition 2024 PMID:38922906

25. J Pediatr Gastroenterol Nutr. 2024 Aug;79(2):371-381. doi: 10.1002/jpn3.12294. Epub 2024 Jun 24. Growth patterns in infants born to women with pregestational overweight/obesity supplemented with docosahexaenoic acid during pregnancy. De Toro V(1), Alberti G(1), Dominguez A(2), Carrasco-Negüe

19.
🧪 RCT
Racial disparity in efficacy of docosahexaenoic acid supplementation for prevention of preterm birth: secondary analysis from a randomized, double-blind trial.
American journal of obstetrics & gynecology MFM 2024 PMID:38552960

15. Am J Obstet Gynecol MFM. 2024 May;6(5):101358. doi: 10.1016/j.ajogmf.2024.101358. Epub 2024 Mar 27. Racial disparity in efficacy of docosahexaenoic acid supplementation for prevention of preterm birth: secondary analysis from a randomized, double-blind trial. DeFranco EA(1), Valentine CJ(2)

20.
📄 연구
Maternal and Offspring Fatty Acid Desaturase Variants, Prenatal DHA Supplementation, and Dietary n-6:n-3 Fatty Acid Ratio in Relation to Cardiometabolic Health in Mexican Children.
The Journal of nutrition 2024 PMID:38453026

46. J Nutr. 2024 May;154(5):1540-1548. doi: 10.1016/j.tjnut.2024.03.004. Epub 2024 Mar 6. Maternal and Offspring Fatty Acid Desaturase Variants, Prenatal DHA Supplementation, and Dietary n-6:n-3 Fatty Acid Ratio in Relation to Cardiometabolic Health in Mexican Children. Wimalasena ST(1), Ramíre

21.
📄 연구
Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women.
Journal of acquired immune deficiency syndromes (1999) 2020 PMID:31929402

2. J Acquir Immune Defic Syndr. 2020 Feb 1;83(2):140-147. doi: 10.1097/QAI.0000000000002237. Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women. Hughes E(1), Mwebaza N(2)(3), Huang L(4), Kajubi R(2), Nguyen V(4)(5)

22.
📄 연구
The effects of vitamin D and omega-3 fatty acid co-supplementation on glycemic control and lipid concentrations in patients with gestational diabetes.
Journal of clinical lipidology 2017 PMID:28502503

31. J Clin Lipidol. 2017 Mar-Apr;11(2):459-468. doi: 10.1016/j.jacl.2017.01.011. Epub 2017 Feb 2. The effects of vitamin D and omega-3 fatty acid co-supplementation on glycemic control and lipid concentrations in patients with gestational diabetes. Jamilian M(1), Samimi M(2), Ebrahimi FA(2), Has

23.
📄 연구
Antiretroviral Therapy With Efavirenz Accentuates Pregnancy-Associated Reduction of Dihydroartemisinin-Piperaquine Exposure During Malaria Chemoprevention.
Clinical pharmacology and therapeutics 2017 PMID:28187497

44. Clin Pharmacol Ther. 2017 Sep;102(3):520-528. doi: 10.1002/cpt.664. Epub 2017 May 30. Antiretroviral Therapy With Efavirenz Accentuates Pregnancy-Associated Reduction of Dihydroartemisinin-Piperaquine Exposure During Malaria Chemoprevention. Kajubi R(1)(2), Huang L(3), Jagannathan P(4), Cham

24.
📄 연구
Population pharmacokinetics, tolerability, and safety of dihydroartemisinin-piperaquine and sulfadoxine-pyrimethamine-piperaquine in pregnant and nonpregnant Papua New Guinean women.
Antimicrobial agents and chemotherapy 2015 PMID:25963981

19. Antimicrob Agents Chemother. 2015 Jul;59(7):4260-71. doi: 10.1128/AAC.00326-15. Epub 2015 May 11. Population pharmacokinetics, tolerability, and safety of dihydroartemisinin-piperaquine and sulfadoxine-pyrimethamine-piperaquine in pregnant and nonpregnant Papua New Guinean women. Benjamin J

25.
📄 연구
Ethanol promotes neuronal apoptosis by inhibiting phosphatidylserine accumulation.
Journal of neuroscience research 2006 PMID:16397898

20. J Neurosci Res. 2006 Feb 15;83(3):432-40. doi: 10.1002/jnr.20744. Ethanol promotes neuronal apoptosis by inhibiting phosphatidylserine accumulation. Akbar M(1), Baick J, Calderon F, Wen Z, Kim HY. Author information: (1)Section of Mass Spectrometry, Laboratory of Membrane Biochemistry and B

26.
📄 연구
Arachidonic acid offsets the effects on mouse brain and behavior of a diet with a low (n-6):(n-3) ratio and very high levels of docosahexaenoic acid.
The Journal of nutrition 1997 PMID:9040564

35. J Nutr. 1997 Jan;127(1):184-93. doi: 10.1093/jn/127.1.184. Arachidonic acid offsets the effects on mouse brain and behavior of a diet with a low (n-6):(n-3) ratio and very high levels of docosahexaenoic acid. Wainwright PE(1), Xing HC, Mutsaers L, McCutcheon D, Kyle D. Author information: (1

27.
📄 연구
Dehydroepiandrosterone sulfate potentiates the effect of interleukin-8 on the cervix.
Gynecologic and obstetric investigation 1996 PMID:8938473

48. Gynecol Obstet Invest. 1996;42(3):191-5. doi: 10.1159/000291952. Dehydroepiandrosterone sulfate potentiates the effect of interleukin-8 on the cervix. Maradny E(1), Kanayama N, Maehara K, Kobayashi T, Terao T. Author information: (1)Department of Obstetrics and Gynecology, Hamamatsu Universi

28.
📄 연구
Maternal plasma phospholipid polyunsaturated fatty acids in early pregnancy and thyroid function throughout pregnancy: a longitudinal study.
The American journal of clinical nutrition 2024 PMID:38408725
📊 RR 0.13 · n=214

14. Am J Clin Nutr. 2024 Apr;119(4):1065-1074. doi: 10.1016/j.ajcnut.2024.02.016. Epub 2024 Feb 24. Maternal plasma phospholipid polyunsaturated fatty acids in early pregnancy and thyroid function throughout pregnancy: a longitudinal study. Li LJ(1), Lu R(2), Rawal S(3), Birukov A(4), Weir NL(5)

29.
📄 연구
Plasma phospholipid polyunsaturated fatty acids composition in early pregnancy and fetal growth trajectories throughout pregnancy: Findings from the US fetal growth studies-singletons cohort.
EBioMedicine 2022 PMID:35853297

21. EBioMedicine. 2022 Aug;82:104180. doi: 10.1016/j.ebiom.2022.104180. Epub 2022 Jul 16. Plasma phospholipid polyunsaturated fatty acids composition in early pregnancy and fetal growth trajectories throughout pregnancy: Findings from the US fetal growth studies-singletons cohort. Li LJ(1), Wu

30.
📋 체계적 리뷰
Epigenetic alterations in preeclampsia: a systematic review of current mechanisms and biomarker potential.
Journal of medicine and life 2026 PMID:41958512

16. J Med Life. 2026 Feb;19(2):69-88. doi: 10.25122/jml-2026-0009. Epigenetic alterations in preeclampsia: a systematic review of current mechanisms and biomarker potential. Crețu OE(1), Poalelungi CV(1)(2), Neacșu AV(1)(2), Nenciu A(1)(2), Ceaușu I(1)(2). Author information: (1)University of M

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