난각막 (NEM)
Eggshell Membrane (NEM)
📖 핵심 요약
📖 30편 · 15분 읽기난각막 (NEM)은(는) 관절·뼈 계열 보충제입니다. 주로 관절, 통증 완화, 피부 분야에서 연구되었으며, PubMed에 30편의 관련 논문이 있습니다.
🔍 연구 분야별 근거
* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)
📚 관련 논문 (30편) · 📊 정량 근거 2건
1. Nutrients. 2025 Aug 3;17(15):2547. doi: 10.3390/nu17152547. Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis. Zhang Y(1), Gui Y(2), Adams R(2)(3), Farragher J(4), Itsiopoulos C(4), Bow K(4), Cai M(2), Han J(1)(2). Author in
2. Nutrients. 2024 Aug 10;16(16):2640. doi: 10.3390/nu16162640. Efficacy of Eggshell Membrane in Knee Osteoarthritis: A Systematic Review and Meta-Analysis. García-Muñoz AM(1), Abellán-Ruiz MS(2), García-Guillén AI(3), Victoria-Montesinos D(1). Author information: (1)Faculty of Pharmacy and Nut
3. Nutrients. 2022 Jun 3;14(11):2340. doi: 10.3390/nu14112340. Randomised Clinical Trial to Analyse the Efficacy of Eggshell Membrane to Improve Joint Functionality in Knee Osteoarthritis. Cánovas F(1), Abellán-Ruíz MS(1), García-Muñoz AM(1), Luque-Rubia AJ(1), Victoria-Montesinos D(1), Pérez-Pi
4. J Med Food. 2021 Mar;24(3):292-298. doi: 10.1089/jmf.2020.0034. Epub 2020 Jul 2. Mildly Processed Natural Eggshell Membrane Alleviates Joint Pain Associated with Osteoarthritis of the Knee: A Randomized Double-Blind Placebo-Controlled Study. Kiers JL(1), Bult JHF(2). Author information: (1)JL
5. J Cosmet Dermatol. 2020 Jun;19(6):1463-1472. doi: 10.1111/jocd.13275. Epub 2020 Jan 6. The effect of oral hydrolyzed eggshell membrane on the appearance of hair, skin, and nails in healthy middle-aged adults: A randomized double-blind placebo-controlled clinical trial. Kalman DS(1), Hewlings
6. J Med Food. 2019 Sep;22(9):875-884. doi: 10.1089/jmf.2019.0068. Epub 2019 Aug 5. A Randomized, Double-Blind, Placebo-Controlled, Prospective Clinical Trial Evaluating Water-Soluble Chicken Eggshell Membrane for Improvement in Joint Health in Adults with Knee Osteoarthritis. Hewlings S(1), Kal
7. Clin Interv Aging. 2018 Feb 19;13:285-295. doi: 10.2147/CIA.S153782. eCollection 2018. Beneficial effects of natural eggshell membrane versus placebo in exercise-induced joint pain, stiffness, and cartilage turnover in healthy, postmenopausal women. Ruff KJ(1), Morrison D(2), Duncan SA(2), B
8. Clin Rheumatol. 2009 Aug;28(8):907-14. doi: 10.1007/s10067-009-1173-4. Epub 2009 Apr 2. Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study. Ruff KJ(1), Winkler A, Jackson RW, DeV
9. Gels. 2026 Apr 10;12(4):324. doi: 10.3390/gels12040324. Short Eggshell Membrane Nanofibers-Chitosan Hydrogel with Dual-Functional Hemostasis and Shape Memory for Non-Compressible Wounds. Zhao S(1), Jiang W(1), Gou Y(1), Zhu S(1), Yuan Y(1), Li B(1), Yuan H(1). Author information: (1)School of
10. Compr Rev Food Sci Food Saf. 2026 May;25(3):e70485. doi: 10.1111/1541-4337.70485. Eggshell Membrane: Composition, Extraction, Functional Properties, and High-Value Applications in Functional Foods and Nutraceuticals. Zhang Y(1)(2)(3)(4), Wen Z(1)(2)(3)(4), Wei T(1)(2)(3)(4), Wu N(1)(2)(3)(4)
11. Molecules. 2026 Apr 7;31(7):1217. doi: 10.3390/molecules31071217. Scalable Jet-O-Mized Eggshell Membrane Processing for Bioactives Promoting Gut Health. Younes M(1), Ahmed TAE(1), Hammami R(2), Hincke MT(1)(3). Author information: (1)Department of Cellular and Molecular Medicine, Faculty of
12. Tissue Cell. 2026 Apr 6;101:103516. doi: 10.1016/j.tice.2026.103516. Online ahead of print. Long-term eggshell membrane supplementation contributes to sustained bone mass by suppressing bone resorption in rats. Yashima N(1), Minamizono W(2), Suito H(3), Okunuki T(4), Fujikawa K(5), Nakai S(
13. PLoS One. 2026 Apr 3;21(4):e0346166. doi: 10.1371/journal.pone.0346166. eCollection 2026. Study on the therapeutic effect of eggshell membrane on osteoarthritis in rats. Pan M(1), Shen Y(1), Wu J(2), Liu C(1), Zhu M(2), Zhou Z(1). Author information: (1)Laboratory Animal Center of Suzhou Med
14. Front Vet Sci. 2026 Feb 26;13:1711135. doi: 10.3389/fvets.2026.1711135. eCollection 2026. Natural eggshell membrane supplementation for chronic lameness in warmblood horses: a 12-week prospective before-after study. Kwon YS(1), Jeong H(2), Kim J(3), Kim J(4), Chun K(5), Yang SK(6), Kim B(7).
15. Int J Biol Macromol. 2026 Apr;357:151301. doi: 10.1016/j.ijbiomac.2026.151301. Epub 2026 Mar 10. Sustainable 3D printed alginate dialdehyde-gelatin scaffolds reinforced with eggshell particles for enhanced bone regeneration. Geske M(1), Kim M(2), Davari N(3), Schobel L(4), Roether JA(5), Boc
47. ACS Appl Mater Interfaces. 2026 Mar 18;18(10):14696-14709. doi: 10.1021/acsami.5c25453. Epub 2026 Mar 5. Sustainable Eggshell-Based Amorphous Calcium Phosphate Scaffolds and Membrane Protein Hydrogel for Regeneration in Rabbit Femoral and Calvarial Defects. Ma Q(1), Staudigel KA(1)(2), Ruben
24. ACS Biomater Sci Eng. 2026 Apr 13;12(4):2270-2284. doi: 10.1021/acsbiomaterials.5c01343. Epub 2026 Feb 27. Therapeutic Potential of Mn- and Ce-Doped Bioactive Glass-Eggshell Membrane Composites in Critical Skin Wound Repair. Das P(1), Sarkar T(2), Swamy BN(3), Datta P(4), Veena P(3), Rajesh
14. J Nanobiotechnology. 2026 Feb 19;24(1):273. doi: 10.1186/s12951-026-04179-7. Bioactive eggshell membrane-integrated nanofiber dressing with mesoporous polydopamine-mediated sustained dexamethasone delivery for enhanced wound regeneration. Han L(#)(1)(2), Feng H(#)(1), Yuan Z(#)(1)(3), Shafiq
2. Biosci Rep. 2026 Jan 9;46(1):BSR20253696. doi: 10.1042/BSR20253696. Dietary eggshell membrane modulates gut microbiota and alleviates AOM/DSS-induced colonic inflammation in mice. Yin W(1), Ma S(2)(3), Igarashi M(2)(4), Li X(2), Suzuki-Kemuyama N(5), Hasebe Y(6), Kato H(2)(7), Jia H(2). Auth
11. Int J Mol Sci. 2025 Sep 18;26(18):9102. doi: 10.3390/ijms26189102. Pharmacokinetic Profiling Using (3)H-Labeled Eggshell Membrane and Effects of Eggshell Membrane and Lysozyme Oral Supplementation on DSS-Induced Colitis and Human Gut Microbiota. Shimizu M(1), Sugai W(1), Ohto-Fujita E(1), At
35. Tissue Cell. 2026 Feb;98:103117. doi: 10.1016/j.tice.2025.103117. Epub 2025 Sep 2. Eggshell membrane supplementation stimulates angiogenesis and promotes bone healing in a rat drill-hole injury model. Yashima N(1), Minamizono W(2), Suito H(3), Okunuki T(4), Fujikawa K(5), Nakai S(6), Ohsako
28. Nutrients. 2024 Jun 14;16(12):1885. doi: 10.3390/nu16121885. Time-Dependent Effect of Eggshell Membrane on Monosodium-Iodoacetate-Induced Osteoarthritis: Early-Stage Inflammation Control and Late-Stage Cartilage Protection. Yu M(1), Park C(1), Son YB(1), Jo SE(1), Jeon SH(1), Kim YJ(1), Han
19. Bone Rep. 2024 May 24;21:101776. doi: 10.1016/j.bonr.2024.101776. eCollection 2024 Jun. Eggshell membrane as promising supplement to maintain bone health: A systematic review. Fladerer JP(1)(2), Grollitsch S(1). Author information: (1)Institute of Pharmaceutical Sciences, University of Graz
23. J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2088-2101. doi: 10.1002/jcsm.13019. Epub 2022 Jun 19. Eggshell membrane modulates gut microbiota to prevent murine pre-cachexia through suppression of T helper cell differentiation. Jia H(1), Lyu W(1), Hirota K(1), Saito E(1), Miyoshi M(1), Hohjoh
1. Front Nutr. 2022 May 19;9:895665. doi: 10.3389/fnut.2022.895665. eCollection 2022. Dietary Eggshell Membrane Powder Improves Survival Rate and Ameliorates Gut Dysbiosis in Interleukin-10 Knockout Mice. Yang Y(1)(2)(3), Jia H(3), Lyu W(3), Furukawa K(3), Li X(3), Hasebe Y(4), Kato H(3). Auth
27. An Acad Bras Cienc. 2026 Apr 10;98(1):e20250520. doi: 10.1590/0001-3765202620250520. eCollection 2026. Physical Properties of Cassava Starch Bioplastic Fortified with Gelatin from Indonesian Native Chicken Eggshell Membrane. Wahyuningsih R(1), Ahyani K(2), Syarifah SM(2), Trinugraha AC(1), W
21. Food Res Int. 2026 Mar 31;228:118163. doi: 10.1016/j.foodres.2025.118163. Epub 2025 Dec 22. Production of peptide-calcium chelates from eggshell membranes: A comparison of high-pressure homogenization versus enzymatic hydrolysis. Qi Y(1), Wang S(1), Li Z(1), Yan X(1), Yang Y(1), Li B(1), Lia
15. Bioresour Technol. 2026 Apr;446:134192. doi: 10.1016/j.biortech.2026.134192. Epub 2026 Feb 9. Dual-functional eggshell-derived system for comprehensive phosphorus recovery from agricultural wastewater: From laboratory validation to pilot-scale implementation. Wu Q(1), Fan M(2), Zheng X(3),
48. Front Nutr. 2026 Jan 14;12:1689701. doi: 10.3389/fnut.2025.1689701. eCollection 2025. Comparative effects of MKARE® eggshell membrane and hydrolyzed collagen as nutricosmetics on skin biophysical properties: a randomized clinical trial. González-Rodríguez Y(#)(1), La Nuez-García MA(#)(2), Ji
31. Skin Res Technol. 2026 Jan;32(1):e70325. doi: 10.1111/srt.70325. Enhancing Wound Healing with a Novel Alginate/Eggshell Membrane-Based Hydrogel Enriched with Red Ginseng Roots and Centella Asiatica. Esmaeili S(1), Rahmati M(2), Salehi M(3)(4)(5), Yahaya BH(6), Zamani S(1). Author information
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