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포자형 유산균

Spore-based Probiotic

📑 PubMed 12편 🦠 프로바이오틱스 🗓️ 최신 2025
🧪 RCT 1

📖 핵심 요약

📖 12편 · 6분 읽기

포자형 유산균은(는) 프로바이오틱스 계열 보충제입니다. 주로 간 건강, 장 건강 분야에서 연구되었으며, PubMed에 12편의 관련 논문이 있습니다.

🔍 연구 분야별 근거

간 건강 논문 1편
장 건강 논문 2편

* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)

💊⚠️ 약물 상호작용 (1)

아래 약을 복용 중이라면 이 보충제 병용 전 반드시 의사·약사와 상의하세요.

항생제 전반 ℹ️ 경미

영향: 효과 감소 가능

대처: 2-3시간 간격으로 복용 (항생제 → 2-3h → 프로바이오틱스)

📚 관련 논문 (12편)

1.
📄 연구
In Vitro Analysis of an Alkalihalobacillus clausii Spore-Based Probiotic Formulation Clarifies the Mechanisms Underlying Its Beneficial Properties.
Biomolecules 2025 PMID:41008601

1. Biomolecules. 2025 Sep 8;15(9):1294. doi: 10.3390/biom15091294. In Vitro Analysis of an Alkalihalobacillus clausii Spore-Based Probiotic Formulation Clarifies the Mechanisms Underlying Its Beneficial Properties. Mazzantini D(1), Calvigioni M(1), Celandroni F(1), Saba A(2), Ghelardi E(1)(3). A

2.
📄 연구
Orally-deliverable liposome-microgel complexes dynamically remodel intestinal environment to enhance probiotic ulcerative colitis therapy via TLR4 inhibition and tryptophan metabolic crosstalk.
Biomaterials 2025 PMID:40233710

2. Biomaterials. 2025 Oct;321:123339. doi: 10.1016/j.biomaterials.2025.123339. Epub 2025 Apr 11. Orally-deliverable liposome-microgel complexes dynamically remodel intestinal environment to enhance probiotic ulcerative colitis therapy via TLR4 inhibition and tryptophan metabolic crosstalk. Fu Y

3.
📄 연구
Alterations in infant gut microbiome composition and metabolism after exposure to glyphosate and Roundup and/or a spore-based formulation using the SHIME technology.
Gut microbiome (Cambridge, England) 2022 PMID:39295780

3. Gut Microbiome (Camb). 2022 Jul 26;3:e6. doi: 10.1017/gmb.2022.5. eCollection 2022. Alterations in infant gut microbiome composition and metabolism after exposure to glyphosate and Roundup and/or a spore-based formulation using the SHIME technology. Mesnage R(1), Calatayud M(2), Duysburgh C(

4.
📄 연구
Treatment with a spore-based probiotic containing five strains of Bacillus induced changes in the metabolic activity and community composition of the gut microbiota in a SHIME® model of the human gastrointestinal system.
Food research international (Ottawa, Ont.) 2021 PMID:34600678

4. Food Res Int. 2021 Nov;149:110676. doi: 10.1016/j.foodres.2021.110676. Epub 2021 Aug 30. Treatment with a spore-based probiotic containing five strains of Bacillus induced changes in the metabolic activity and community composition of the gut microbiota in a SHIME® model of the human gastroin

5.
📄 연구
Probiotic Bacillus Spores Together with Amino Acids and Immunoglobulins Exert Protective Effects on a Rat Model of Ulcerative Colitis.
Nutrients 2020 PMID:33255321

5. Nutrients. 2020 Nov 24;12(12):3607. doi: 10.3390/nu12123607. Probiotic Bacillus Spores Together with Amino Acids and Immunoglobulins Exert Protective Effects on a Rat Model of Ulcerative Colitis. Catinean A(1), Neag MA(2), Krishnan K(3), Muntean DM(4), Bocsan CI(2), Pop RM(2), Mitre AO(5), Me

6.
🧪 RCT
Efficacy of Spore Forming Bacilli Supplementation in Patients with Mild to Moderate Elevation of Triglycerides: A 12 week, Randomized, Double-Blind, Placebo Controlled Trial.
Integrative medicine (Encinitas, Calif.) 2020 PMID:33041703

6. Integr Med (Encinitas). 2020 Apr;19(2):22-27. Efficacy of Spore Forming Bacilli Supplementation in Patients with Mild to Moderate Elevation of Triglycerides: A 12 week, Randomized, Double-Blind, Placebo Controlled Trial. Campbell AW(1), Sinatra D(2), Zhang Z(3), Sinatra ST(4). Author informa

7.
📄 연구
Effects of pea extrusion and enzyme and probiotic supplementation on performance, microbiota activity and biofilm formation in the broiler gastrointestinal tract.
British poultry science 2018 PMID:30070146

7. Br Poult Sci. 2018 Dec;59(6):654-662. doi: 10.1080/00071668.2018.1507017. Epub 2018 Oct 24. Effects of pea extrusion and enzyme and probiotic supplementation on performance, microbiota activity and biofilm formation in the broiler gastrointestinal tract. Konieczka P(1), Nowicka K(1), Madar M

8.
📄 연구
Oral Spore-Based Probiotic Supplementation Alters Post-Prandial Expression of mRNA Associated with Gastrointestinal Health.
Biomedicines 2024 PMID:39457699

8. Biomedicines. 2024 Oct 18;12(10):2386. doi: 10.3390/biomedicines12102386. Oral Spore-Based Probiotic Supplementation Alters Post-Prandial Expression of mRNA Associated with Gastrointestinal Health. McFarlin BK(1)(2), Deemer SE(1), Bridgeman EA(1)(2). Author information: (1)Applied Physiology

9.
📄 연구
Prospective Placebo-Controlled Assessment of Spore-Based Probiotic Supplementation on Sebum Production, Skin Barrier Function, and Acne.
Journal of clinical medicine 2023 PMID:36769543

9. J Clin Med. 2023 Jan 23;12(3):895. doi: 10.3390/jcm12030895. Prospective Placebo-Controlled Assessment of Spore-Based Probiotic Supplementation on Sebum Production, Skin Barrier Function, and Acne. Rybak I(1), Haas KN(2), Dhaliwal SK(1), Burney WA(3), Pourang A(1)(4), Sandhu SS(5), Maloh J(3)

10.
📄 연구
Oral spore-based probiotic supplementation was associated with reduced incidence of post-prandial dietary endotoxin, triglycerides, and disease risk biomarkers.
World journal of gastrointestinal pathophysiology 2017 PMID:28868181

10. World J Gastrointest Pathophysiol. 2017 Aug 15;8(3):117-126. doi: 10.4291/wjgp.v8.i3.117. Oral spore-based probiotic supplementation was associated with reduced incidence of post-prandial dietary endotoxin, triglycerides, and disease risk biomarkers. McFarlin BK(1), Henning AL(1), Bowman EM(

11.
📄 연구
Engineering a probiotic Bacillus subtilis for acetaldehyde removal: A hag locus integration to robustly express acetaldehyde dehydrogenase.
PloS one 2024 PMID:39509360

11. PLoS One. 2024 Nov 7;19(11):e0312457. doi: 10.1371/journal.pone.0312457. eCollection 2024. Engineering a probiotic Bacillus subtilis for acetaldehyde removal: A hag locus integration to robustly express acetaldehyde dehydrogenase. Hassan-Casarez C(1), Ryan V(1), Shuster BM(1), Oliver JWK(1),

12.
📄 연구
Survival and persistence of Bacillus clausii in the human gastrointestinal tract following oral administration as spore-based probiotic formulation.
Journal of applied microbiology 2015 PMID:25973914

12. J Appl Microbiol. 2015 Aug;119(2):552-9. doi: 10.1111/jam.12848. Epub 2015 Jun 16. Survival and persistence of Bacillus clausii in the human gastrointestinal tract following oral administration as spore-based probiotic formulation. Ghelardi E(1)(2), Celandroni F(1), Salvetti S(1), Gueye SA(1

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