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단삼

Salvia miltiorrhiza (Danshen)

📑 PubMed 30편 🏮 전통 한방 🗓️ 최신 2026
🔬 메타분석 7 📋 체계적 리뷰 1 🧪 RCT 5

📖 핵심 요약

📖 30편 · 15분 읽기

단삼은(는) 전통 한방 계열 보충제입니다. 주로 장 건강, 심혈관, 당뇨 분야에서 연구되었으며, PubMed에 30편의 관련 논문이 있습니다.

🔍 연구 분야별 근거

장 건강 논문 3편
심혈관 논문 3편
당뇨 논문 1편

* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)

📚 관련 논문 (30편) · 📊 정량 근거 1건

1.
🔬 메타분석
[Network Meta-analysis of traditional Chinese medicine injections combined with conventional western medicine for treatment of chronic obstructive pulmonary disease with respiratory failure].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 2026 PMID:41814776

1. Zhongguo Zhong Yao Za Zhi. 2026 Jan;51(1):281-300. doi: 10.19540/j.cnki.cjcmm.20250917.501. [Network Meta-analysis of traditional Chinese medicine injections combined with conventional western medicine for treatment of chronic obstructive pulmonary disease with respiratory failure]. [Article

2.
🔬 메타분석
The efficacy and potential pharmacological mechanism of Fufang Danshen Tablet in promoting the rehabilitation of ischemic stroke: a meta-analysis and in silico study.
Frontiers in neurology 2026 PMID:41767015

2. Front Neurol. 2026 Feb 12;17:1724630. doi: 10.3389/fneur.2026.1724630. eCollection 2026. The efficacy and potential pharmacological mechanism of Fufang Danshen Tablet in promoting the rehabilitation of ischemic stroke: a meta-analysis and in silico study. Zeng X(#)(1)(2)(3), Nie Y(#)(2)(3)(4

3.
🔬 메타분석
Comparative efficacy and safety of Chinese patent medicines in coronary heart disease patients after percutaneous coronary intervention: A systematic review and network meta-analysis.
Journal of ethnopharmacology 2026 PMID:41740818
📊 SMD -1.01 (95% CI -1.35–-0.66) · n=524

3. J Ethnopharmacol. 2026 May 23;363:121377. doi: 10.1016/j.jep.2026.121377. Epub 2026 Feb 23. Comparative efficacy and safety of Chinese patent medicines in coronary heart disease patients after percutaneous coronary intervention: A systematic review and network meta-analysis. Wang A(1), Wei J

4.
🔬 메타분석
Therapeutic potential of pharmacological components of Salvia miltiorrhiza against atherosclerosis: A preclinical systematic review and meta-analysis.
Journal of ethnopharmacology 2026 PMID:41690432

4. J Ethnopharmacol. 2026 May 23;363:121294. doi: 10.1016/j.jep.2026.121294. Epub 2026 Feb 13. Therapeutic potential of pharmacological components of Salvia miltiorrhiza against atherosclerosis: A preclinical systematic review and meta-analysis. Zhang J(1), Sun X(2), Wang Q(3), Sun Z(4), Liu W(1

5.
📄 연구
Regulation of Traditional Chinese Medicine Gut Microbiota Short-Chain Fatty Acid Axis in Type 2 Diabetes Management: A Review.
The American journal of Chinese medicine 2026 PMID:41582084

5. Am J Chin Med. 2026;54(1):35-63. doi: 10.1142/S0192415X26500011. Epub 2026 Jan 26. Regulation of Traditional Chinese Medicine Gut Microbiota Short-Chain Fatty Acid Axis in Type 2 Diabetes Management: A Review. Yang R(1), Zhou Y(1), Shen Y(1), Liu J(2), Shi Y(3), Yang Y(4). Author information

6.
🔬 메타분석
Different traditional Chinese medicine injections combined with conventional therapy for sepsis-induced myocardial dysfunction: a systematic review and network meta-analysis.
Frontiers in pharmacology 2025 PMID:41560744

6. Front Pharmacol. 2026 Jan 5;16:1688113. doi: 10.3389/fphar.2025.1688113. eCollection 2025. Different traditional Chinese medicine injections combined with conventional therapy for sepsis-induced myocardial dysfunction: a systematic review and network meta-analysis. Deng W(1), Fang X(2), Huan

7.
📄 연구
Salvia miltiorrhiza for Viral Myocarditis: Multi-Computational Pharmacological Exploration and Meta-Analytic Efficacy Validation.
International journal of molecular sciences 2025 PMID:41373898

7. Int J Mol Sci. 2025 Dec 4;26(23):11753. doi: 10.3390/ijms262311753. Salvia miltiorrhiza for Viral Myocarditis: Multi-Computational Pharmacological Exploration and Meta-Analytic Efficacy Validation. Cao X(1), Li M(1), Xie X(1)(2), Feng Z(1), Jin W(1), Li Y(1), Yang F(1), Duan S(1), He Z(1). A

8.
📋 체계적 리뷰
Salviae Miltiorrhizae Radix et Rhizoma protects against doxorubicin-induced cardiotoxicity: A systematic review.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 PMID:41138578

8. Phytomedicine. 2025 Nov 25;148:157244. doi: 10.1016/j.phymed.2025.157244. Epub 2025 Sep 8. Salviae Miltiorrhizae Radix et Rhizoma protects against doxorubicin-induced cardiotoxicity: A systematic review. Yue MY(1), Zhao WR(2), Wang SS(3), Zhang J(4), Shi WT(5), Tang JY(6), Zhou ZY(7). Autho

9.
🔬 메타분석
Potential preventive effects of selected traditional Chinese medicine as adjuvant therapy on hypertensive heart disease progression by replenishing qi and activating blood circulation: a systematic review and meta-analysis of clinical trials.
Frontiers in pharmacology 2025 PMID:41111519

9. Front Pharmacol. 2025 Oct 2;16:1506234. doi: 10.3389/fphar.2025.1506234. eCollection 2025. Potential preventive effects of selected traditional Chinese medicine as adjuvant therapy on hypertensive heart disease progression by replenishing qi and activating blood circulation: a systematic revi

10.
🔬 메타분석
Efficacy and safety of traditional Chinese medicine combined with immunomodulators in treating erosive oral lichen planus: A network meta-analysis of randomized controlled trials.
Medicine 2025 PMID:41029064

10. Medicine (Baltimore). 2025 Sep 26;104(39):e44832. doi: 10.1097/MD.0000000000044832. Efficacy and safety of traditional Chinese medicine combined with immunomodulators in treating erosive oral lichen planus: A network meta-analysis of randomized controlled trials. Li Y(1), Guo X(2), Deng L(1

11.
🧪 RCT
A Randomized Phase 2 Study to Evaluate Efficacy and Safety of AR36 for Prevention of Acute Mountain Sickness.
Wilderness & environmental medicine 2023 PMID:37923683

11. Wilderness Environ Med. 2023 Dec;34(4):498-508. doi: 10.1016/j.wem.2023.09.002. Epub 2023 Nov 1. A Randomized Phase 2 Study to Evaluate Efficacy and Safety of AR36 for Prevention of Acute Mountain Sickness. Schober A(1), Chinn G(1), Eichbaum Y(1), Dudley M(1), Sall JW(2); University of Cali

12.
🧪 RCT
Guanxin Danshen Dripping Pills Improve Quality of Life and Cardiovascular Prognoses of CHD Patients after PCI with Anxiety or Depression (GLAD Study): A Randomized Double-Blind Placebo-Controlled Study.
Chinese journal of integrative medicine 2023 PMID:36301456

12. Chin J Integr Med. 2023 Mar;29(3):195-204. doi: 10.1007/s11655-022-3688-3. Epub 2022 Oct 27. Guanxin Danshen Dripping Pills Improve Quality of Life and Cardiovascular Prognoses of CHD Patients after PCI with Anxiety or Depression (GLAD Study): A Randomized Double-Blind Placebo-Controlled Stu

13.
📄 연구
Effect of Salvia Miltiorrhiza Polyphenolic Acid Injection on Improving Limb Use and Cognitive Impairment in Patients with Acute Stroke.
Computational and mathematical methods in medicine 2022 PMID:35983530

13. RETRACTED ARTICLE Comput Math Methods Med. 2022 Aug 9;2022:1481294. doi: 10.1155/2022/1481294. eCollection 2022. Effect of Salvia Miltiorrhiza Polyphenolic Acid Injection on Improving Limb Use and Cognitive Impairment in Patients with Acute Stroke. Cong S(1), Dong C(2), Hu Y(3), Wang C(1),

14.
📄 연구
Effect of Compound Danshen Injection Combined with Magnesium Sulfate on Oxidative Stress, TNF-α, NO, and Therapeutic Efficacy in Severe Preeclampsia.
Computational intelligence and neuroscience 2022 PMID:35898773

14. Comput Intell Neurosci. 2022 Jul 18;2022:9789066. doi: 10.1155/2022/9789066. eCollection 2022. Effect of Compound Danshen Injection Combined with Magnesium Sulfate on Oxidative Stress, TNF-α, NO, and Therapeutic Efficacy in Severe Preeclampsia. Zhou Y(1), Wang J(2), Wang L(3), Tang J(4), Zha

15.
🧪 RCT
Combination of Activating Blood Circulation and Detoxifying Chinese Medicines Played an Anti-Inflammatory Role in Unstable Angina Patients after Percutaneous Coronary Intervention: A Multicenter, Open-Labeled, Randomized Controlled Trial.
Chinese journal of integrative medicine 2021 PMID:34532749

15. Chin J Integr Med. 2021 Nov;27(11):803-810. doi: 10.1007/s11655-021-2878-8. Epub 2021 Sep 16. Combination of Activating Blood Circulation and Detoxifying Chinese Medicines Played an Anti-Inflammatory Role in Unstable Angina Patients after Percutaneous Coronary Intervention: A Multicenter, Op

16.
🧪 RCT
A randomized controlled study on an integrated approach to prevent and treat re-adhesion after transcervical resection of moderate-to-severe intrauterine adhesions.
Clinics (Sao Paulo, Brazil) 2021 PMID:33978070

26. Clinics (Sao Paulo). 2021 May 5;76:e1987. doi: 10.6061/clinics/2021/e1987. eCollection 2021. A randomized controlled study on an integrated approach to prevent and treat re-adhesion after transcervical resection of moderate-to-severe intrauterine adhesions. Pan LZ(1), Wang Y(1), Chen X(1).

17.
📄 연구
Tanshinone I and Tanshinone IIA/B attenuate LPS-induced mastitis via regulating the NF-κB.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 PMID:33578236

34. Biomed Pharmacother. 2021 May;137:111353. doi: 10.1016/j.biopha.2021.111353. Epub 2021 Feb 9. Tanshinone I and Tanshinone IIA/B attenuate LPS-induced mastitis via regulating the NF-κB. Yang L(1), Zhou G(2), Liu J(1), Song J(1), Zhang Z(1), Huang Q(1), Wei F(3). Author information: (1)Depart

18.
📄 연구
Efficacy of Salvia officinalis extract on the prevention of insulin resistance in euglycemic patients with polycystic ovary syndrome: A double-blinded placebo-controlled clinical trial.
Complementary therapies in medicine 2020 PMID:31987228

1. Complement Ther Med. 2020 Jan;48:102245. doi: 10.1016/j.ctim.2019.102245. Epub 2019 Nov 13. Efficacy of Salvia officinalis extract on the prevention of insulin resistance in euglycemic patients with polycystic ovary syndrome: A double-blinded placebo-controlled clinical trial. Amini L(1), Mo

19.
📄 연구
Interaction of clopidogrel and fufang danshen dripping pills assay in coronary heart disease based on non-target metabolomics.
Journal of ethnopharmacology 2019 PMID:30703494

23. J Ethnopharmacol. 2019 Apr 24;234:189-196. doi: 10.1016/j.jep.2019.01.030. Epub 2019 Jan 28. Interaction of clopidogrel and fufang danshen dripping pills assay in coronary heart disease based on non-target metabolomics. Guo MZ(1), Wang TY(2), Yang J(3), Chang H(4), Ji S(5), Tang DQ(6). Auth

20.
🧪 RCT
Synergistic Effects of Sanghuang⁻Danshen Bioactives on Arterial Stiffness in a Randomized Clinical Trial of Healthy Smokers: An Integrative Approach to in silico Network Analysis.
Nutrients 2019 PMID:30621047

45. Nutrients. 2019 Jan 7;11(1):108. doi: 10.3390/nu11010108. Synergistic Effects of Sanghuang⁻Danshen Bioactives on Arterial Stiffness in a Randomized Clinical Trial of Healthy Smokers: An Integrative Approach to in silico Network Analysis. Lim Y(1), Song TJ(2), Hwang W(3), Kim JY(4), Lee D(5),

21.
📄 연구
Cardiovascular Benefits of Salvia miltiorrhiza (Danshen) Supplementation: Bioactive Constituents, Mechanisms, Clinical Evidence and Implications for Nutritional Care.
Food science & nutrition 2026 PMID:42052427

30. Food Sci Nutr. 2026 Apr 26;14(5):e71755. doi: 10.1002/fsn3.71755. eCollection 2026 May. Cardiovascular Benefits of Salvia miltiorrhiza (Danshen) Supplementation: Bioactive Constituents, Mechanisms, Clinical Evidence and Implications for Nutritional Care. Vikal A(1), Maurya R(2), Patel P(3),

22.
📄 연구
Molecular mechanism of Danshen injection in treating endometrial fibrosis induced by intrauterine adhesions via the LAMC2-CD44-TGF-β1-SMAD2/3 signaling pathway.
Frontiers in physiology 2026 PMID:42037995

49. Front Physiol. 2026 Apr 10;17:1794215. doi: 10.3389/fphys.2026.1794215. eCollection 2026. Molecular mechanism of Danshen injection in treating endometrial fibrosis induced by intrauterine adhesions via the LAMC2-CD44-TGF-β1-SMAD2/3 signaling pathway. Tang S(1), Hu R(1), Weng S(1), Luo M(1).

23.
📄 연구
The multifaceted mechanisms of Tanshinone IIA in doxorubicin-induced cardiotoxicity.
Frontiers in medicine 2026 PMID:41958587

46. Front Med (Lausanne). 2026 Mar 25;13:1783433. doi: 10.3389/fmed.2026.1783433. eCollection 2026. The multifaceted mechanisms of Tanshinone IIA in doxorubicin-induced cardiotoxicity. Wang Q(#)(1), Zou D(#)(1), Chen H(1), Cui D(2), Huang X(1), Chen Y(2), Qi Y(2), Nan Z(3), Wang X(2), Shang X(2

24.
📄 연구
Study on the Pharmacodynamic Substances and Mechanism of Danshen-Honghua Herb Pair (DHHP) Against Myocardial Ischemia Based on the Gut Microbiota Metabolism.
Chemistry & biodiversity 2026 PMID:41958121

17. Chem Biodivers. 2026 Apr;23(4):e02338. doi: 10.1002/cbdv.202502338. Study on the Pharmacodynamic Substances and Mechanism of Danshen-Honghua Herb Pair (DHHP) Against Myocardial Ischemia Based on the Gut Microbiota Metabolism. Dong Z(1), Deng Q(1), Xue Z(1), Zhou H(1), Bai J(2), Bai J(1), Wang

25.
📄 연구
Baihe Dihuang-Danshen Decoction in Myocardial Ischemia-reperfusion Injury: Network Pharmacology and Experimental Validation.
Current computer-aided drug design 2026 PMID:41928640

14. Curr Comput Aided Drug Des. 2026 Mar 25. doi: 10.2174/0115734099391795251203142647. Online ahead of print. Baihe Dihuang-Danshen Decoction in Myocardial Ischemia-reperfusion Injury: Network Pharmacology and Experimental Validation. Huang L(1), Zhang L(2), Xu Q(2), Huang W(1), Zhang S(3), Liu

26.
📄 연구
Therapeutic Potential of Salvia miltiorrhiza Active Components in Various Diseases Based on the PI3K/Akt Signaling Pathway.
Chemistry & biodiversity 2026 PMID:41883102

11. Chem Biodivers. 2026 Mar;23(3):e03444. doi: 10.1002/cbdv.202503444. Therapeutic Potential of Salvia miltiorrhiza Active Components in Various Diseases Based on the PI3K/Akt Signaling Pathway. Cheng B(1), Chen Y(1), Cai F(2), Wen X(1). Author information: (1)Jiangxi University of Chinese Medi

27.
📄 연구
Dihydrotanshinone I Induces Ferroptosis in Rhabdomyosarcoma by Targeting HSP90AA1/RACK1/AKT Axis.
Phytotherapy research : PTR 2026 PMID:41879514

50. Phytother Res. 2026 Mar 25. doi: 10.1002/ptr.70295. Online ahead of print. Dihydrotanshinone I Induces Ferroptosis in Rhabdomyosarcoma by Targeting HSP90AA1/RACK1/AKT Axis. Liao Q(1)(2), Hu J(3)(4), Wu Z(5), Jiang Y(6), Cheng D(2), Chen H(2). Author information: (1)Department of Oncology, Th

28.
📄 연구
Correction to "Danshen-Enhanced Cardioprotective Effect of Cardioplegia on Ischemia Reperfusion Injury in a Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Model".
Artificial organs 2026 PMID:41847874

49. Artif Organs. 2026 Mar;50(3):483. doi: 10.1111/aor.70109. Epub 2026 Mar 18. Correction to "Danshen-Enhanced Cardioprotective Effect of Cardioplegia on Ischemia Reperfusion Injury in a Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Model". [No authors listed] Erratum for Arti

29.
📄 연구
[Protective effect of Renshen-Danshen on myocardial ischemia-reperfusion injury in rats based on SIRT3/PGC-1α/VDAC1 signaling pathway].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 2026 PMID:41814770

26. Zhongguo Zhong Yao Za Zhi. 2026 Jan;51(1):221-231. doi: 10.19540/j.cnki.cjcmm.20250728.301. [Protective effect of Renshen-Danshen on myocardial ischemia-reperfusion injury in rats based on SIRT3/PGC-1α/VDAC1 signaling pathway]. [Article in Chinese] Ran QZ(1), Chen HW(1). Author information

30.
📄 연구
Salvianolic acids modulate lifespan and gut microbiota composition in amyloid-β-expressing Drosophila melanogaster.
World journal of microbiology & biotechnology 2024 PMID:39428437

22. World J Microbiol Biotechnol. 2024 Oct 21;40(11):358. doi: 10.1007/s11274-024-04163-z. Salvianolic acids modulate lifespan and gut microbiota composition in amyloid-β-expressing Drosophila melanogaster. Go W(1), Ishak IH(1), Zarkasi KZ(2), Azzam G(3). Author information: (1)School of Biolog

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