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리코펜 (전립선)

Lycopene (Prostate)

📑 PubMed 22편 ♂️ 남성 🗓️ 최신 2026
🔬 메타분석 3 📋 체계적 리뷰 5

📖 핵심 요약

📖 22편 · 11분 읽기

리코펜 (전립선)은(는) 남성 계열 보충제입니다. 주로 항암 분야에서 연구되었으며, PubMed에 22편의 관련 논문이 있습니다.

🔍 연구 분야별 근거

항암 논문 14편

* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)

📊 효과 크기 분포 (Forest plot)

각 연구의 효과 추정치와 95% 신뢰구간. 개별 연구를 통합(pooling)하지 않고 그대로 표시합니다.

35031434-0.12 (-0.62–0.38)33355018-0.6 (-2.01–0.81)-2.401.2MD (favours ← / →)

📚 관련 논문 (22편) · 📊 정량 근거 4건

1.
🔬 메타분석
The effect of lycopene supplement from different sources on prostate specific antigen (PSA): A systematic review and meta-analysis of randomized controlled trials.
Complementary therapies in medicine 2022 PMID:35031434
📊 MD -0.12 (95% CI -0.62–0.38)

1. Complement Ther Med. 2022 Mar;64:102801. doi: 10.1016/j.ctim.2022.102801. Epub 2022 Jan 11. The effect of lycopene supplement from different sources on prostate specific antigen (PSA): A systematic review and meta-analysis of randomized controlled trials. Sharifi-Zahabi E(1), Soltani S(2), M

2.
🔬 메타분석
Lycopene Does Not Affect Prostate-Specific Antigen in Men with Non-Metastatic Prostate Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Nutrition and cancer 2021 PMID:33355018
📊 MD -0.6 (95% CI -2.01–0.81)

2. Nutr Cancer. 2021;73(11-12):2796-2807. doi: 10.1080/01635581.2020.1862254. Epub 2020 Dec 23. Lycopene Does Not Affect Prostate-Specific Antigen in Men with Non-Metastatic Prostate Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Sadeghian M(1)(2), Asadi M(1)(2),

3.
📄 연구
Diet, anthropometric measures and prostate cancer risk: a review of prospective cohort and intervention studies.
BJU international 2004 PMID:15142129

3. BJU Int. 2004 May;93(8):1139-50. doi: 10.1111/j.1464-410X.2004.04795.x. Diet, anthropometric measures and prostate cancer risk: a review of prospective cohort and intervention studies. Dagnelie PC(1), Schuurman AG, Goldbohm RA, Van den Brandt PA. Author information: (1)Department of Epidemiol

4.
📄 연구
Diet, nutrition and prostate cancer.
International journal of cancer 1997 PMID:9209014

4. Int J Cancer. 1997;Suppl 10:13-7. doi: 10.1002/(sici)1097-0215(1997)10+<13::aid-ijc5>3.0.co;2-c. Diet, nutrition and prostate cancer. Giles G(1), Ireland P. Author information: (1)Cancer Epidemiology Centre, Anti-Cancer Council of Victoria, Carlton South, Australia. ggg@accv.org.au Although

5.
📄 연구
Lycopene intake and prostate cancer risk in men at high cardiovascular risk: a prospective cohort study.
BMC medicine 2025 PMID:41214650
📊 HR 0.46 (95% CI 0.23–0.95) · n=2970

5. BMC Med. 2025 Nov 10;23(1):627. doi: 10.1186/s12916-025-04440-0. Lycopene intake and prostate cancer risk in men at high cardiovascular risk: a prospective cohort study. López-Solís R(1)(2), Castro-Barquero S(2)(3)(4), Donat-Vargas C(1)(2)(3), Corrado M(1)(2)(3), Arancibia-Riveros C(1)(2), Ma

6.
📄 연구
Lycopene enhances the sensitivity of castration-resistant prostate cancer to enzalutamide through the AKT/EZH2/ androgen receptor signaling pathway.
Biochemical and biophysical research communications 2022 PMID:35533600

6. Biochem Biophys Res Commun. 2022 Jul 12;613:53-60. doi: 10.1016/j.bbrc.2022.04.126. Epub 2022 Apr 30. Lycopene enhances the sensitivity of castration-resistant prostate cancer to enzalutamide through the AKT/EZH2/ androgen receptor signaling pathway. Chen X(1), Yang G(2), Liu M(2), Quan Z(2),

7.
📄 연구
The anti-cancer effects of carotenoids and other phytonutrients resides in their combined activity.
Archives of biochemistry and biophysics 2015 PMID:25711533

7. Arch Biochem Biophys. 2015 Apr 15;572:28-35. doi: 10.1016/j.abb.2015.02.018. Epub 2015 Feb 21. The anti-cancer effects of carotenoids and other phytonutrients resides in their combined activity. Linnewiel-Hermoni K(1), Khanin M(1), Danilenko M(1), Zango G(1), Amosi Y(1), Levy J(1), Sharoni Y

8.
📄 연구
Lycopene and the LXRα agonist T0901317 synergistically inhibit the proliferation of androgen-independent prostate cancer cells via the PPARγ-LXRα-ABCA1 pathway.
The Journal of nutritional biochemistry 2012 PMID:22137263

8. J Nutr Biochem. 2012 Sep;23(9):1155-62. doi: 10.1016/j.jnutbio.2011.06.009. Epub 2011 Dec 1. Lycopene and the LXRα agonist T0901317 synergistically inhibit the proliferation of androgen-independent prostate cancer cells via the PPARγ-LXRα-ABCA1 pathway. Yang CM(1), Lu YL, Chen HY, Hu ML. Aut

9.
📄 연구
Synergistic effect between lycopene and ciprofloxacin on a chronic bacterial prostatitis rat model.
International journal of antimicrobial agents 2008 PMID:17920247

9. Int J Antimicrob Agents. 2008 Feb;31 Suppl 1:S102-7. doi: 10.1016/j.ijantimicag.2007.07.016. Epub 2007 Oct 24. Synergistic effect between lycopene and ciprofloxacin on a chronic bacterial prostatitis rat model. Han CH(1), Yang CH, Sohn DW, Kim SW, Kang SH, Cho YH. Author information: (1)Depa

10.
📄 연구
Complementary and alternative medicine patients are talking about: lycopene.
Clinical journal of oncology nursing 2005 PMID:15853167

10. Clin J Oncol Nurs. 2005 Apr;9(2):245-6. doi: 10.1188/05.CJON.245-246. Complementary and alternative medicine patients are talking about: lycopene. Lee CO(1). Author information: (1)Office of Cancer Complementary and Alternative Medicine at the National Cancer Institute in Bethesda, MD, USA.

11.
📄 연구
Lycopene for prevention and treatment of prostate cancer.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2004 PMID:15372829

11. Am J Health Syst Pharm. 2004 Aug 1;61(15):1562-6. doi: 10.1093/ajhp/61.15.1562. Lycopene for prevention and treatment of prostate cancer. Everson KM(1), McQueen CE. Author information: (1)Drug Information Center, University of Missouri-Kansas City, 64108, USA. DOI: 10.1093/ajhp/61.15.1562 PM

12.
📄 연구
Re: Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets.
Journal of the National Cancer Institute 2004 PMID:15069119

12. J Natl Cancer Inst. 2004 Apr 7;96(7):554; author reply 554-5. doi: 10.1093/jnci/djh089. Re: Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. Limpens J, van Weerden WM, Krämer K, Pallapies D, Obermüller-

13.
📄 연구
Lycopene in association with alpha-tocopherol inhibits at physiological concentrations proliferation of prostate carcinoma cells.
Biochemical and biophysical research communications 1998 PMID:9784387

13. Biochem Biophys Res Commun. 1998 Sep 29;250(3):582-5. doi: 10.1006/bbrc.1998.9351. Lycopene in association with alpha-tocopherol inhibits at physiological concentrations proliferation of prostate carcinoma cells. Pastori M(1), Pfander H, Boscoboinik D, Azzi A. Author information: (1)Institu

14.
📄 연구
Liarozole amplifies retinoid-induced apoptosis in human prostate cancer cells.
Anti-cancer drugs 1996 PMID:8792006

14. Anticancer Drugs. 1996 May;7(3):312-20. doi: 10.1097/00001813-199605000-00012. Liarozole amplifies retinoid-induced apoptosis in human prostate cancer cells. Hall AK(1). Author information: (1)Department of Pharmacology, University of Cambridge, UK. Beta-carotene, canthaxanthin and retinoic

15.
📋 체계적 리뷰
Nutritional and Lifestyle Interventions for Prostate Cancer Patients Undergoing Radiotherapy: A Systematic Review.
Nutrition and cancer 2026 PMID:41776849

15. Nutr Cancer. 2026;78(4-5):279-294. doi: 10.1080/01635581.2026.2637661. Epub 2026 Mar 3. Nutritional and Lifestyle Interventions for Prostate Cancer Patients Undergoing Radiotherapy: A Systematic Review. Han Y(1), Gong Y(1), Zhang W(1), Liang Y(1), Jia Z(1), Yang L(1), Zhang H(1). Author inf

16.
📋 체계적 리뷰
Influence of Lycopene Intake on Mental Health: A Systematic Review of Randomized Controlled Trials (RCTs).
Nutrients 2025 PMID:40507061

31. Nutrients. 2025 May 25;17(11):1793. doi: 10.3390/nu17111793. Influence of Lycopene Intake on Mental Health: A Systematic Review of Randomized Controlled Trials (RCTs). Głąbska D(1), Guzek D(2), Jílková A(3), Kołota-Burdzy A(1), Skolmowska D(1), Kouřimská L(3). Author information: (1)Departm

17.
📋 체계적 리뷰
Etiology of prostate cancer with the TMPRSS2:ERG fusion: A systematic review of risk factors.
International journal of cancer 2025 PMID:39663641

17. Int J Cancer. 2025 May 15;156(10):1898-1908. doi: 10.1002/ijc.35279. Epub 2024 Dec 11. Etiology of prostate cancer with the TMPRSS2:ERG fusion: A systematic review of risk factors. McGrath CB(1), Shreves AH(1)(2)(3), Shanahan MR(1), Guard HE(1), Nhliziyo MV(1), Pernar CH(1), Penney KL(1)(4)

18.
📋 체계적 리뷰
The Anti-Cancer Activity of Lycopene: A Systematic Review of Human and Animal Studies.
Nutrients 2022 PMID:36501182

8. Nutrients. 2022 Dec 3;14(23):5152. doi: 10.3390/nu14235152. The Anti-Cancer Activity of Lycopene: A Systematic Review of Human and Animal Studies. Kapała A(1), Szlendak M(2), Motacka E(1). Author information: (1)Department of Clinical Nutrition, Maria Skłodowska-Curie National Research Insti

19.
📄 연구
Tomato and lycopene and multiple health outcomes: Umbrella review.
Food chemistry 2021 PMID:33131949

23. Food Chem. 2021 May 1;343:128396. doi: 10.1016/j.foodchem.2020.128396. Epub 2020 Oct 15. Tomato and lycopene and multiple health outcomes: Umbrella review. Li N(1), Wu X(2), Zhuang W(2), Xia L(2), Chen Y(2), Wu C(3), Rao Z(4), Du L(5), Zhao R(2), Yi M(2), Wan Q(2), Zhou Y(6). Author informa

20.
📄 연구
Non-hormonal treatment for male infertility: the potential role of Serenoa repens, selenium and lycopene.
European review for medical and pharmacological sciences 2019 PMID:31002161

23. Eur Rev Med Pharmacol Sci. 2019 Apr;23(7):3112-3120. doi: 10.26355/eurrev_201904_17595. Non-hormonal treatment for male infertility: the potential role of Serenoa repens, selenium and lycopene. Cannarella R(1), Calogero AE, Condorelli RA, Giacone F, Mongioi' LM, La Vignera S. Author inform

21.
📋 체계적 리뷰
Can Lycopene Impact the Androgen Axis in Prostate Cancer?: A Systematic Review of Cell Culture and Animal Studies.
Nutrients 2019 PMID:30875962

8. Nutrients. 2019 Mar 15;11(3):633. doi: 10.3390/nu11030633. Can Lycopene Impact the Androgen Axis in Prostate Cancer?: A Systematic Review of Cell Culture and Animal Studies. Applegate CC(1), Rowles JL 3rd(2), Erdman JW Jr(3)(4). Author information: (1)Division of Nutritional Sciences, Univers

22.
🔬 메타분석
[Efficacy of lycopene intake in primary prevention of prostate cancer: a systematic review of the literature and meta-analysis.].
Archivos espanoles de urologia 2018 PMID:29521265
📊 OR 0.94 · n=417

23. Arch Esp Urol. 2018 Mar;71(2):187-197. [Efficacy of lycopene intake in primary prevention of prostate cancer: a systematic review of the literature and meta-analysis.]. [Article in Spanish] Cataño JG(1), Trujillo CG(2), Caicedo JI(2), Bravo-Balado A(2), Robledo D(2), Mariño-Alvarez AM(2), P

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