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Effect of lactase supplementation on infant colic: Systematic review of randomized controlled trials.

1. J Pediatr Gastroenterol Nutr. 2024 May;78(5):1009-1016. doi: 10.1002/jpn3.12144. Epub 2024 Mar 1. Effect of lactase supplementation on infant colic: Systematic review of randomized controlled trials. Kozłowska-Jalowska A(1), Stróżyk A(1), Horvath A(1), Szajewska H(1). Author information: (1)

Dietary modifications for infantile colic.

2. Cochrane Database Syst Rev. 2018 Oct 10;10(10):CD011029. doi: 10.1002/14651858.CD011029.pub2. Dietary modifications for infantile colic. Gordon M(1), Biagioli E, Sorrenti M, Lingua C, Moja L, Banks SS, Ceratto S, Savino F. Author information: (1)School of Medicine, University of Central Lanc

Recent advances on lactose intolerance: Tolerance thresholds and currently available answers.

3. Crit Rev Food Sci Nutr. 2017 Oct 13;57(15):3344-3356. doi: 10.1080/10408398.2015.1123671. Recent advances on lactose intolerance: Tolerance thresholds and currently available answers. Corgneau M(1), Scher J(1), Ritie-Pertusa L(2), Le DTL(2), Petit J(1), Nikolova Y(1), Banon S(1), Gaiani C(1)

Infant Colic-What works: A Systematic Review of Interventions for Breast-fed Infants.

4. J Pediatr Gastroenterol Nutr. 2016 May;62(5):668-86. doi: 10.1097/MPG.0000000000001075. Infant Colic-What works: A Systematic Review of Interventions for Breast-fed Infants. Harb T(1), Matsuyama M, David M, Hill RJ. Author information: (1)*Child Health Research Centre, Children's Nutrition R

Dose-Dependent Effects of Catecholaminergic Modulation on Interference Control: Role of Baseline GABA and Glx in Cortico-Subcortical Networks.

5. Hum Brain Mapp. 2025 Oct 15;46(15):e70385. doi: 10.1002/hbm.70385. Dose-Dependent Effects of Catecholaminergic Modulation on Interference Control: Role of Baseline GABA and Glx in Cortico-Subcortical Networks. Koyun AH(1)(2), Werner A(3), Kuntke P(3), Roessner V(1)(4), Beste C(1)(2)(4), Stock

Tolerance of protein-hydrolyzed lactose-free A1 milk and A2 milk in lactose-tolerant and lactose-intolerant volunteers: A randomized crossover trial with 2 parallel groups.

6. J Dairy Sci. 2025 Sep;108(9):9062-9077. doi: 10.3168/jds.2025-26712. Epub 2025 Jul 3. Tolerance of protein-hydrolyzed lactose-free A1 milk and A2 milk in lactose-tolerant and lactose-intolerant volunteers: A randomized crossover trial with 2 parallel groups. Mannila E(1), Hokkanen L(1), Ahon

Lactase-Treated A2 Milk as a Feasible Conventional Milk Alternative: Results of a Randomized Controlled Crossover Trial to Assess Tolerance, Gastrointestinal Distress, and Preference for Milks Varying in Casein Types and Lactose Content.

7. Nutrients. 2025 Jun 6;17(12):1946. doi: 10.3390/nu17121946. Lactase-Treated A2 Milk as a Feasible Conventional Milk Alternative: Results of a Randomized Controlled Crossover Trial to Assess Tolerance, Gastrointestinal Distress, and Preference for Milks Varying in Casein Types and Lactose Conte

Oral lactase for infantile colic: a randomized double-blind placebo-controlled trial.

8. BMC Pediatr. 2022 Aug 3;22(1):468. doi: 10.1186/s12887-022-03531-8. Oral lactase for infantile colic: a randomized double-blind placebo-controlled trial. Narang M(1), Shah D(2). Author information: (1)Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics,

[Efficacy and safety of lactase additive in preterm infants with lactose intolerance: a prospective randomized controlled trial].

9. Zhongguo Dang Dai Er Ke Za Zhi. 2021 Jul;23(7):671-676. doi: 10.7499/j.issn.1008-8830.2102038. [Efficacy and safety of lactase additive in preterm infants with lactose intolerance: a prospective randomized controlled trial]. [Article in Chinese] Wang L(1), Wang YW(1), Tan JT(1), Yan J(1), Wu

Synergistic treatment of sodium propionate and Sishen Pill for diarrhea mice with kidney-yang deficiency syndrome.

10. Front Cell Infect Microbiol. 2025 Jun 2;15:1608271. doi: 10.3389/fcimb.2025.1608271. eCollection 2025. Synergistic treatment of sodium propionate and Sishen Pill for diarrhea mice with kidney-yang deficiency syndrome. Guo M(1), Di J(1), Lei Z(1). Author information: (1)School of Pharmacy, H

Sucrose produces withdrawal and dopamine-sensitive reinforcing effects in planarians.

11. Physiol Behav. 2013 Mar 15;112-113:8-13. doi: 10.1016/j.physbeh.2013.02.002. Epub 2013 Feb 13. Sucrose produces withdrawal and dopamine-sensitive reinforcing effects in planarians. Zhang C(1), Tallarida CS, Raffa RB, Rawls SM. Author information: (1)Department of Pharmacology, Temple Univer

Glucocorticoids modulate neurotransmitter-induced glycogen metabolism in cultured cortical astrocytes.

12. J Neurochem. 2004 Feb;88(4):900-8. doi: 10.1046/j.1471-4159.2003.02235.x. Glucocorticoids modulate neurotransmitter-induced glycogen metabolism in cultured cortical astrocytes. Allaman I(1), Pellerin L, Magistretti PJ. Author information: (1)Institut de Physiologie, Faculté de Médecine, Univ

Geraniol, a component of plant essential oils, sensitizes human colonic cancer cells to 5-Fluorouracil treatment.

13. J Pharmacol Exp Ther. 2002 May;301(2):625-30. doi: 10.1124/jpet.301.2.625. Geraniol, a component of plant essential oils, sensitizes human colonic cancer cells to 5-Fluorouracil treatment. Carnesecchi S(1), Langley K, Exinger F, Gosse F, Raul F. Author information: (1)Laboratory of Cancer Nu

Effect of cyclosporine A on the gastrointestinal absorption of acyclovir in neonatal and adult rats.

14. Biol Neonate. 1998;74(3):243-52. doi: 10.1159/000014030. Effect of cyclosporine A on the gastrointestinal absorption of acyclovir in neonatal and adult rats. Mizuno N(1), Takagi C, Yamamoto N, Takahashi K. Author information: (1)School of Pharmaceutical Sciences, Mukogawa Women's University,

Potentiation of butyrate-induced differentiation in human colon tumor cells by deoxycholate.

15. Cancer Lett. 1993 May 14;69(3):181-6. doi: 10.1016/0304-3835(93)90172-6. Potentiation of butyrate-induced differentiation in human colon tumor cells by deoxycholate. Desai TK(1), Nathan DF, Morin MJ. Author information: (1)Section of Gastroenterology, Northwestern University Medical School,

Synergistic effects of thyroxine and dexamethasone on enzyme ontogeny in rat small intestine.

35. Pediatr Res. 1992 Sep;32(3):306-11. doi: 10.1203/00006450-199209000-00012. Synergistic effects of thyroxine and dexamethasone on enzyme ontogeny in rat small intestine. McDonald MC(1), Henning SJ. Author information: (1)Department of Pediatrics, Baylor College of Medicine, Houston, Texas 770

Pituitary regulation of postnatal small intestinal ontogeny in the rat: differential regulation of digestive hydrolase maturation by thyroxine and growth hormone.

31. Endocrinology. 1991 Sep;129(3):1417-23. doi: 10.1210/endo-129-3-1417. Pituitary regulation of postnatal small intestinal ontogeny in the rat: differential regulation of digestive hydrolase maturation by thyroxine and growth hormone. Castillo RO(1), Glasscock GF, Noren KM, Reisenauer AM. Aut

The effect of thyroid hormone on the activities of lactase in the culture of fetal rat intestine.

23. Cell Biol Int Rep. 1990 Dec;14(12):1143-8. doi: 10.1016/0309-1651(90)90023-r. The effect of thyroid hormone on the activities of lactase in the culture of fetal rat intestine. Shimizu K(1), Nose O, Okada S. Author information: (1)Department of Pediatrics, Osaka Medical School, Japan. The ef

Effect of epidermal growth factor on the expression of digestive hydrolases in the jejunum and colon of newborn rats.

4. Endocrinology. 1990 Oct;127(4):1763-9. doi: 10.1210/endo-127-4-1763. Effect of epidermal growth factor on the expression of digestive hydrolases in the jejunum and colon of newborn rats. Foltzer-Jourdainne C(1), Raul F. Author information: (1)Institut National de la Santé et de la Recherche M

Changes in gut microbiota and lactose intolerance symptoms before and after daily lactose supplementation in individuals with the lactase nonpersistent genotype.

30. Am J Clin Nutr. 2024 Mar;119(3):702-710. doi: 10.1016/j.ajcnut.2023.12.016. Epub 2023 Dec 28. Changes in gut microbiota and lactose intolerance symptoms before and after daily lactose supplementation in individuals with the lactase nonpersistent genotype. JanssenDuijghuijsen L(1), Looijeste

Development of a novel SNP assay to detect lactase persistence associated genetic variants.

3. Mol Biol Rep. 2021 Nov;48(11):7087-7093. doi: 10.1007/s11033-021-06698-y. Epub 2021 Sep 13. Development of a novel SNP assay to detect lactase persistence associated genetic variants. De Luca P(1), Iaconis D(2), Biffali E(2), Enza C(3), de Magistris L(3), Riegler G(3), Pappalardo D(3), Amato

Effects of cow's milk beta-casein variants on symptoms of milk intolerance in Chinese adults: a multicentre, randomised controlled study.

40. Nutr J. 2017 Oct 25;16(1):72. doi: 10.1186/s12937-017-0275-0. Effects of cow's milk beta-casein variants on symptoms of milk intolerance in Chinese adults: a multicentre, randomised controlled study. He M(1), Sun J(2), Jiang ZQ(3), Yang YX(4)(5). Author information: (1)Beijing Research Insti

Lactose intolerance and health.

23. Evid Rep Technol Assess (Full Rep). 2010 Feb;(192):1-410. Lactose intolerance and health. Wilt TJ, Shaukat A, Shamliyan T, Taylor BC, MacDonald R, Tacklind J, Rutks I, Schwarzenberg SJ, Kane RL, Levitt M. OBJECTIVES: We systematically reviewed evidence to determine lactose intolerance (LI)

Randomized, double-blind clinical trial of a lactose-free and a lactose-containing formula in dietary management of acute childhood diarrhea.

35. J Med Assoc Thai. 2004 Jun;87(6):641-9. Randomized, double-blind clinical trial of a lactose-free and a lactose-containing formula in dietary management of acute childhood diarrhea. Simakachorn N(1), Tongpenyai Y, Tongtan O, Varavithya W. Author information: (1)Department of Pediatrics, Maha

Lactose (mal)digestion evaluated by the 13C-lactose digestion test.

2. Eur J Clin Invest. 2000 Feb;30(2):140-6. doi: 10.1046/j.1365-2362.2000.00609.x. Lactose (mal)digestion evaluated by the 13C-lactose digestion test. Vonk RJ(1), Lin Y, Koetse HA, Huang C, Zeng G, Elzinga H, Antoine J, Stellaard F. Author information: (1)University of Groningen, Groningen, The

Genetic and environmental factors associated with lactose digestion in African populations.

19. Physiol Genomics. 2026 Jan 1;58(1):32-41. doi: 10.1152/physiolgenomics.00268.2025. Epub 2025 Dec 10. Genetic and environmental factors associated with lactose digestion in African populations. Hakizimana JC(1), Alagbonsi AI(1). Author information: (1)Department of Physiology, School of Medi

Lactase for infantile colic: A systematic review of randomized clinical trials.

37. J Pediatr Gastroenterol Nutr. 2024 Oct;79(4):855-862. doi: 10.1002/jpn3.12231. Epub 2024 May 8. Lactase for infantile colic: A systematic review of randomized clinical trials. Nau AL(1), Bassan AS(2), Cezar AB(3), de Carlos GA(4), Deboni M(5). Author information: (1)Division of Pediatric Gas

Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials.

31. Nutrients. 2020 May 20;12(5):1487. doi: 10.3390/nu12051487. Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials. Leis R(1)(2)(3)(4), de Castro MJ(1)(2)(5), de Lamas C(4), Picáns R(1), Couce ML(1)(2)(4)(5).

Does primary lactase deficiency reduce bone mineral density in postmenopausal women? A systematic review and meta-analysis.

10. Osteoporos Int. 2018 Nov;29(11):2399-2407. doi: 10.1007/s00198-018-4635-1. Epub 2018 Jul 16. Does primary lactase deficiency reduce bone mineral density in postmenopausal women? A systematic review and meta-analysis. Treister-Goltzman Y(1)(2), Friger M(3), Peleg R(4)(5). Author information:

The effects of probiotics in lactose intolerance: A systematic review.

10. Crit Rev Food Sci Nutr. 2019;59(11):1675-1683. doi: 10.1080/10408398.2018.1425977. Epub 2018 Feb 9. The effects of probiotics in lactose intolerance: A systematic review. Oak SJ(1), Jha R(1). Author information: (1)a Department of Human Nutrition , Food and Animal Sciences, College of Tropi