← 전체 보충제 목록

이눌린 (프리바이오틱스)

Inulin (Prebiotic)

📑 PubMed 30편 🦠 프로바이오틱스 🗓️ 최신 2026
🔬 메타분석 6 📋 체계적 리뷰 4 🧪 RCT 7

📖 핵심 요약

📖 30편 · 15분 읽기

이눌린 (프리바이오틱스)은(는) 프로바이오틱스 계열 보충제입니다. 주로 체중 관리, 장 건강, 당뇨 분야에서 연구되었으며, PubMed에 30편의 관련 논문이 있습니다.

🔍 연구 분야별 근거

체중 관리 논문 4편
장 건강 논문 7편
당뇨 논문 2편

* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)

📊 효과 크기 분포 (Forest plot)

각 연구의 효과 추정치와 95% 신뢰구간. 개별 연구를 통합(pooling)하지 않고 그대로 표시합니다.

41059033-0.5440331741-3.8140215676-0.48-4.400.57SMD (favours ← / →)

📚 관련 논문 (30편) · 📊 정량 근거 8건

1.
📄 연구
Meta-analytical insight on probiotic metabolites and inflammatory markers in diabetes.
Frontiers in cellular and infection microbiology 2025 PMID:41059033
📊 SMD -0.54

1. Front Cell Infect Microbiol. 2025 Sep 22;15:1677671. doi: 10.3389/fcimb.2025.1677671. eCollection 2025. Meta-analytical insight on probiotic metabolites and inflammatory markers in diabetes. Xie Y(1), Zheng Y(2), Jiang F(3), Cai X(1). Author information: (1)Department of Endocrinology, Heilo

2.
🔬 메타분석
Inulin Modulates Gut Microbiota and Increases Short-Chain Fatty Acids Levels to Inhibit Colon Tumorigenesis in Rat Models: A Systematic Review and Meta-Analysis.
Journal of food science 2025 PMID:40331741
📊 SMD -3.805

2. J Food Sci. 2025 May;90(5):e70250. doi: 10.1111/1750-3841.70250. Inulin Modulates Gut Microbiota and Increases Short-Chain Fatty Acids Levels to Inhibit Colon Tumorigenesis in Rat Models: A Systematic Review and Meta-Analysis. Yu Y(1), He J(2), Fu H(1), Mi Y(1), Wu H(1), Gao Y(1)(2)(3), Li M(

3.
🔬 메타분석
Effect of prebiotics on growth metrics in infants: A GRADE approach systematic review and meta-analysis of randomized clinical trials.
Nutrition research (New York, N.Y.) 2025 PMID:40215676
📊 SMD -0.479

3. Nutr Res. 2025 May;137:22-46. doi: 10.1016/j.nutres.2025.03.003. Epub 2025 Mar 8. Effect of prebiotics on growth metrics in infants: A GRADE approach systematic review and meta-analysis of randomized clinical trials. Mirzohreh ST(1), Sohrabnavi A(1), Panahi P(1), Nikniaz Z(2), Farhangi MA(3),

4.
🔬 메타분석
Gut microbiome-targeted therapies as adjuvant treatments in inflammatory bowel diseases: a systematic review and network meta-analysis.
Journal of gastroenterology and hepatology 2025 PMID:39482823

4. J Gastroenterol Hepatol. 2025 Jan;40(1):78-88. doi: 10.1111/jgh.16795. Epub 2024 Oct 31. Gut microbiome-targeted therapies as adjuvant treatments in inflammatory bowel diseases: a systematic review and network meta-analysis. Zhang T(1), Li X(1), Li J(1), Sun F(2)(3), Duan L(1). Author inform

5.
🔬 메타분석
The effects of chicory inulin-type fructans supplementation on weight management outcomes: systematic review, meta-analysis, and meta-regression of randomized controlled trials.
The American journal of clinical nutrition 2024 PMID:39313030
📊 MD -0.39 (95% CI -1.34–-0.59) · n=1184

5. Am J Clin Nutr. 2024 Nov;120(5):1245-1258. doi: 10.1016/j.ajcnut.2024.09.019. Epub 2024 Sep 21. The effects of chicory inulin-type fructans supplementation on weight management outcomes: systematic review, meta-analysis, and meta-regression of randomized controlled trials. Reimer RA(1), Thei

6.
🔬 메타분석
Prebiotics for Induction and Maintenance of Remission in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis.
Inflammatory bowel diseases 2025 PMID:38781004

6. Inflamm Bowel Dis. 2025 May 12;31(5):1220-1230. doi: 10.1093/ibd/izae115. Prebiotics for Induction and Maintenance of Remission in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis. Limketkai BN(1)(2), Godoy-Brewer G(3), Shah ND(4), Maas L(5), White J(6), Parian AM(5), Mullin GE

7.
📄 연구
Effect of inulin, galacto-oligosaccharides, and polyphenols on the gut microbiota, with a focus on Akkermansia muciniphila.
Food & function 2024 PMID:38590256

7. Food Funct. 2024 May 7;15(9):4763-4772. doi: 10.1039/d4fo00428k. Effect of inulin, galacto-oligosaccharides, and polyphenols on the gut microbiota, with a focus on Akkermansia muciniphila. Tian R(1)(2), Yu L(1)(2), Tian F(1)(2), Zhao J(1)(2), Chen W(1)(2)(3), Zhai Q(1)(2). Author information

8.
🔬 메타분석
The effects of inulin-type fructans on cardiovascular disease risk factors: systematic review and meta-analysis of randomized controlled trials.
The American journal of clinical nutrition 2024 PMID:38309832
📊 MD -0.06 (95% CI -0.24–-0.05) · n=2518

8. Am J Clin Nutr. 2024 Feb;119(2):496-510. doi: 10.1016/j.ajcnut.2023.10.030. Epub 2024 Jan 5. The effects of inulin-type fructans on cardiovascular disease risk factors: systematic review and meta-analysis of randomized controlled trials. Talukdar JR(1), Cooper M(2), Lyutvyn L(1), Zeraatkar D(

9.
📄 연구
Prebiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants.
The Cochrane database of systematic reviews 2023 PMID:37262358
📊 RR 0.97 (95% CI 0.6–1.56)

9. Cochrane Database Syst Rev. 2023 Jun 1;6(6):CD015133. doi: 10.1002/14651858.CD015133.pub2. Prebiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants. Sharif S(1), Oddie SJ(2), Heath PT(3), McGuire W(1). Author information: (1)Centre for Reviews and Diss

10.
📄 연구
Probiotics for management of functional abdominal pain disorders in children.
The Cochrane database of systematic reviews 2023 PMID:36799531
📊 RR 1.57 (95% CI 1.05–2.36) · n=1309

10. Cochrane Database Syst Rev. 2023 Feb 17;2(2):CD012849. doi: 10.1002/14651858.CD012849.pub2. Probiotics for management of functional abdominal pain disorders in children. Wallace C(1), Gordon M(2), Sinopoulou V(2), Akobeng AK(3). Author information: (1)Pennine Acute Hospitals NHS Trust, Manch

11.
📄 연구
Effect of Prebiotic Supplementation With and Without Physiotherapy on Pain and Pain Sensitivity in People with Knee Osteoarthritis.
Nutrients 2026 PMID:41829888

11. Nutrients. 2026 Feb 24;18(5):714. doi: 10.3390/nu18050714. Effect of Prebiotic Supplementation With and Without Physiotherapy on Pain and Pain Sensitivity in People with Knee Osteoarthritis. Kouraki A(1)(2)(3), Franks S(1)(2)(3), Vijay A(1)(2)(3), Kurien T(1)(2)(3)(4), Taylor MA(1)(5), Smith

12.
📄 연구
Effects of Phenolic-Rich Extra Virgin Olive Oil and Prebiotics on Sarcopenia in Older Adults: FOOP-Sarc Project.
Journal of cachexia, sarcopenia and muscle 2026 PMID:41787835

12. J Cachexia Sarcopenia Muscle. 2026 Apr;17(2):e70247. doi: 10.1002/jcsm.70247. Effects of Phenolic-Rich Extra Virgin Olive Oil and Prebiotics on Sarcopenia in Older Adults: FOOP-Sarc Project. Besora-Moreno M(1), Jiménez-Ten Hoevel C(1), Queral J(1), Bernal G(2), Pérez-Merino L(2), Puzo J(3),

13.
📄 연구
Efficacy of inulin supplementation in metabolic control and Akkermansia muciniphila levels in subjects with type 1 diabetes: a pilot study.
European review for medical and pharmacological sciences 2026 PMID:41636295

13. Eur Rev Med Pharmacol Sci. 2026 Jan;30(1):15-26. doi: 10.26355/eurrev_202601_37645. Efficacy of inulin supplementation in metabolic control and Akkermansia muciniphila levels in subjects with type 1 diabetes: a pilot study. Ojetti V(1), Saviano A, Rizzi A, Tartaglione L, Di Leo M, Quaranta G

14.
🧪 RCT
A randomised, placebo-controlled trial in healthy humans of modified cellulose or psyllium evaluating the role of gelation in altering colonic gas production during inulin co-administration.
Food & function 2026 PMID:41636227

14. Food Funct. 2026 Feb 23;17(4):1794-1805. doi: 10.1039/d5fo03532e. A randomised, placebo-controlled trial in healthy humans of modified cellulose or psyllium evaluating the role of gelation in altering colonic gas production during inulin co-administration. Reid JESJ(1)(2), Alhasani AT(2)(3),

15.
🧪 RCT
Effects of a novel synbiotic intervention on abdominal visceral fat reductions and gut microbiota in overweight and obese adults: A randomized, double-blind, placebo-controlled trial.
Clinical nutrition (Edinburgh, Scotland) 2026 PMID:41512635

15. Clin Nutr. 2026 Feb;57:106560. doi: 10.1016/j.clnu.2025.106560. Epub 2025 Dec 30. Effects of a novel synbiotic intervention on abdominal visceral fat reductions and gut microbiota in overweight and obese adults: A randomized, double-blind, placebo-controlled trial. Li N(1), Zhu Z(2), Wu S(1

16.
🧪 RCT
Standardized Hibiscus-Inulin Shot Lowers Lipid-Glucose Indices in Adults with Overweight and Obesity: 8-Week Randomized Trial.
Nutrients 2025 PMID:41305605

3. Nutrients. 2025 Nov 14;17(22):3556. doi: 10.3390/nu17223556. Standardized Hibiscus-Inulin Shot Lowers Lipid-Glucose Indices in Adults with Overweight and Obesity: 8-Week Randomized Trial. Mendivil EJ(1), Rivera-Iñiguez I(2), Arellano-Gómez LP(3), Martínez-López E(4), Hernández-Guerrero C(1),

17.
🧪 RCT
Evaluation of antenatal prebiotic intake in infants at risk of atopy: the double-blind PREGRALL randomized clinical trial.
The British journal of dermatology 2026 PMID:41250898
📊 OR 1.01 (95% CI 0.59–1.74) · n=188

24. Br J Dermatol. 2026 Feb 18;194(3):441-449. doi: 10.1093/bjd/ljaf414. Evaluation of antenatal prebiotic intake in infants at risk of atopy: the double-blind PREGRALL randomized clinical trial. Barbarot S(1)(2), Aubert H(2), Boivin M(3), Foureau A(2), Maruani A(4), Droitcourt C(5), Mazereeuw-H

18.
🧪 RCT
Inulin-induced improvements on bowel habit and gut microbiota in adults with functional constipation: findings of a randomized, double-blind, placebo-controlled study.
BMC gastroenterology 2025 PMID:41233756

28. BMC Gastroenterol. 2025 Nov 13;25(1):806. doi: 10.1186/s12876-025-04409-6. Inulin-induced improvements on bowel habit and gut microbiota in adults with functional constipation: findings of a randomized, double-blind, placebo-controlled study. Puhlmann ML(1)(2)(3), Wegh CAM(4)(5), van der Zal

19.
📄 연구
The anti-inflammatory effects of three different dietary supplement interventions.
Journal of translational medicine 2025 PMID:41094562

36. J Transl Med. 2025 Oct 16;23(1):1081. doi: 10.1186/s12967-025-07167-x. The anti-inflammatory effects of three different dietary supplement interventions. Vijay A(1), Simpson L(2), Tooley M(2), Turley S(3), Kouraki A(4), Kelly A(4), Menni C(5)(6)(7), Armstrong J(8), Jones S(8), Valdes AM(4).

20.
🧪 RCT
A randomized trial of inulin for bowel symptoms, depression and quality of life in constipation predominant IBS.
Scientific reports 2025 PMID:41034384

16. Sci Rep. 2025 Oct 1;15(1):34252. doi: 10.1038/s41598-025-16321-w. A randomized trial of inulin for bowel symptoms, depression and quality of life in constipation predominant IBS. Akçalı Ç(1), Uçar A(2), Atay K(3). Author information: (1)Department of Nutrition and Dietetics, Faculty of Healt

21.
📄 연구
Synergistic Effects of Short- and Long-Chain Fructans: A Novel Strategy for Mitigating Ovalbumin Allergy via Microbiome-Driven Acetate Production.
Journal of nutritional science and vitaminology 2025 PMID:40582875

13. J Nutr Sci Vitaminol (Tokyo). 2025;71(3):238-247. doi: 10.3177/jnsv.71.238. Synergistic Effects of Short- and Long-Chain Fructans: A Novel Strategy for Mitigating Ovalbumin Allergy via Microbiome-Driven Acetate Production. Takahashi H(1)(2)(3), Fujii T(2)(3)(4), Yamada C(1), Fujiki K(1), Kond

22.
📄 연구
Interactions of probiotics and prebiotics with the gut microbiota.
Progress in molecular biology and translational science 2020 PMID:32475525

4. Prog Mol Biol Transl Sci. 2020;171:265-300. doi: 10.1016/bs.pmbts.2020.03.008. Epub 2020 Apr 24. Interactions of probiotics and prebiotics with the gut microbiota. Ballan R(1), Battistini C(1), Xavier-Santos D(2), Saad SMI(3). Author information: (1)Department of Pharmaceutical and Biochemica

23.
🧪 RCT
The Profile of Urinary Headspace Volatile Organic Compounds After 12-Week Intake of Oligofructose-Enriched Inulin by Children and Adolescents with Celiac Disease on a Gluten-Free Diet: Results of a Pilot, Randomized, Placebo-Controlled Clinical Trial.
Molecules (Basel, Switzerland) 2019 PMID:30959740

24. Molecules. 2019 Apr 5;24(7):1341. doi: 10.3390/molecules24071341. The Profile of Urinary Headspace Volatile Organic Compounds After 12-Week Intake of Oligofructose-Enriched Inulin by Children and Adolescents with Celiac Disease on a Gluten-Free Diet: Results of a Pilot, Randomized, Placebo-Co

24.
📄 연구
Better Management of Alcohol Liver Disease Using a 'Microstructured Synbox' System Comprising L. plantarum and EGCG.
PloS one 2017 PMID:28060832

20. PLoS One. 2017 Jan 6;12(1):e0168459. doi: 10.1371/journal.pone.0168459. eCollection 2017. Better Management of Alcohol Liver Disease Using a 'Microstructured Synbox' System Comprising L. plantarum and EGCG. Rishi P(1), Arora S(1), Kaur UJ(1), Chopra K(2), Kaur IP(2). Author information: (1)

25.
📄 연구
Single or combined effects of Lactobacillus sakei and inulin on growth, non-specific immunity and IgM expression in leopard grouper (Mycteroperca rosacea).
Fish physiology and biochemistry 2014 PMID:24464476

11. Fish Physiol Biochem. 2014 Aug;40(4):1169-80. doi: 10.1007/s10695-014-9913-z. Epub 2014 Jan 24. Single or combined effects of Lactobacillus sakei and inulin on growth, non-specific immunity and IgM expression in leopard grouper (Mycteroperca rosacea). Reyes-Becerril M(1), Ascencio F, Gracia

26.
📄 연구
Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats.
Carcinogenesis 2002 PMID:12419846

42. Carcinogenesis. 2002 Nov;23(11):1953-60. doi: 10.1093/carcin/23.11.1953. Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats. Fe

27.
📋 체계적 리뷰
Impact of non-digestible carbohydrates and prebiotics on immunity, infections, inflammation and vaccine responses: a systematic review of evidence in healthy humans and a discussion of mechanistic proposals.
Critical reviews in food science and nutrition 2026 PMID:40516031

42. Crit Rev Food Sci Nutr. 2026;66(1):1-74. doi: 10.1080/10408398.2025.2514700. Epub 2025 Jun 14. Impact of non-digestible carbohydrates and prebiotics on immunity, infections, inflammation and vaccine responses: a systematic review of evidence in healthy humans and a discussion of mechanistic

28.
📋 체계적 리뷰
Potential effects of prebiotic fibers on dental caries: a systematic review.
Journal of the science of food and agriculture 2025 PMID:39812321

42. J Sci Food Agric. 2025 Aug 30;105(11):5640-5651. doi: 10.1002/jsfa.14113. Epub 2025 Jan 15. Potential effects of prebiotic fibers on dental caries: a systematic review. Fernández CE(1), Maturana-Valenzuela C(1), Rojas-Castillo N(1), Rosier B(2). Author information: (1)Cariology Unit, Departm

29.
📋 체계적 리뷰
Microbiota-Focused Dietary Approaches to Support Health: A Systematic Review.
The Journal of nutrition 2025 PMID:39486521

14. J Nutr. 2025 Feb;155(2):381-401. doi: 10.1016/j.tjnut.2024.10.043. Epub 2024 Oct 31. Microbiota-Focused Dietary Approaches to Support Health: A Systematic Review. Hindle VK(1), Veasley NM(2), Holscher HD(3). Author information: (1)Department of Food Science and Human Nutrition, University of

30.
📋 체계적 리뷰
Emerging mycotoxins and preventive strategies related to gut microbiota changes: probiotics, prebiotics, and postbiotics - a systematic review.
Food & function 2024 PMID:39229841

9. Food Funct. 2024 Sep 16;15(18):8998-9023. doi: 10.1039/d4fo01705f. Emerging mycotoxins and preventive strategies related to gut microbiota changes: probiotics, prebiotics, and postbiotics - a systematic review. Lázaro Á(1), Vila-Donat P(1), Manyes L(1). Author information: (1)Biotech Agrifood

🔗 같은 분류의 보충제

⚠️ 면책 고지

이 정보는 일반 교육 목적이며 의료 진단/처방을 대체하지 않습니다.