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히알루론산 (경구)

Hyaluronic Acid (Oral)

📑 PubMed 30편 🌿 허브 🗓️ 최신 2026
🔬 메타분석 2 🧪 RCT 9

📖 핵심 요약

📖 30편 · 15분 읽기

히알루론산 (경구)은(는) 허브 계열 보충제입니다. 주로 피부 분야에서 연구되었으며, PubMed에 30편의 관련 논문이 있습니다.

🔍 연구 분야별 근거

피부 논문 3편

* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)

📚 관련 논문 (30편) · 📊 정량 근거 2건

1.
📄 연구
Oral Hyaluronic Acid Supplement: Efficacy in Skin Hydration, Elasticity, and Wrinkle Depth Reduction.
Journal of drugs in dermatology : JDD 2025 PMID:40911749

1. J Drugs Dermatol. 2025 Sep 1;24(9):910-919. doi: 10.36849/jdd.8542. Oral Hyaluronic Acid Supplement: Efficacy in Skin Hydration, Elasticity, and Wrinkle Depth Reduction. Amin P, Sarabi A, Choe S, Scott S, Suh S, Mesinkovska NA. BACKGROUND: Hyaluronic acid (HA) is a key component naturally pre

2.
🔬 메타분석
Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysis.
Indian journal of dermatology, venereology and leprology 2025 PMID:40826844
📊 SMD 1.25 · n=646

2. Indian J Dermatol Venereol Leprol. 2025 Nov-Dec;91(6):730-740. doi: 10.25259/IJDVL_1165_2023. Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysis. Danessa G(1), Notario D(2), Regina R(3). Author information: (1)Bachelor of Medicine,

3.
📄 연구
Stem cell injections for osteoarthritis of the knee.
The Cochrane database of systematic reviews 2025 PMID:40169165
📊 RR 0.72 (95% CI 1.1–1.53) · n=1341

3. Cochrane Database Syst Rev. 2025 Apr 2;4(4):CD013342. doi: 10.1002/14651858.CD013342.pub2. Stem cell injections for osteoarthritis of the knee. Whittle SL(1)(2), Johnston RV(1), McDonald S(3), Worthley D(4), Campbell TM(5), Cyril S(1), Bapna T(1), Zhang J(1), Buchbinder R(1). Author informat

4.
🔬 메타분석
Hyaluronic acid efficacy in root coverage procedures: a systematic review and meta-analysis.
BMC oral health 2025 PMID:39844152

4. BMC Oral Health. 2025 Jan 22;25(1):119. doi: 10.1186/s12903-025-05526-0. Hyaluronic acid efficacy in root coverage procedures: a systematic review and meta-analysis. Talebi Ardakani M(1)(2), Moscowchi A(3), Talebi A(4), Talebi MH(5). Author information: (1)Dental Research Center, Research Ins

5.
📄 연구
Circulating Metabolites Treat Human TMJ-OA by Eliminating Senescent Chondrocytes via the C1QBP/C1q/p14ARF Axis.
Journal of extracellular vesicles 2026 PMID:41619174

5. J Extracell Vesicles. 2026 Feb;15(2):e70224. doi: 10.1002/jev2.70224. Circulating Metabolites Treat Human TMJ-OA by Eliminating Senescent Chondrocytes via the C1QBP/C1q/p14ARF Axis. Meng B(#)(1), Li X(#)(2)(3), Yang B(#)(1), Qu Y(#)(1), He Y(1), Fu C(1), An Z(1), Wu A(2)(3), Hei Y(2)(3), Zhan

6.
📄 연구
Platelet-rich plasma versus hyaluronic acid injection following arthrocentesis for temporomandibular joint disorders under sedation: a comparative clinical study.
Oral and maxillofacial surgery 2026 PMID:41514013

6. Oral Maxillofac Surg. 2026 Jan 10;30(1):15. doi: 10.1007/s10006-025-01502-8. Platelet-rich plasma versus hyaluronic acid injection following arthrocentesis for temporomandibular joint disorders under sedation: a comparative clinical study. Mahdi MS(1), Abdulsattar MS(2). Author information:

7.
🧪 RCT
Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults.
Scientific reports 2025 PMID:41422283

7. Sci Rep. 2025 Dec 20;16(1):2941. doi: 10.1038/s41598-025-32758-5. Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults. Dolečková I(1), Kušnierik P(2), Berka V(2), Šimek M(2), Matějková

8.
📄 연구
Efficacy and Tolerability of a Topical Peptide-Hyaluronic Acid Lip Treatment Using a Novel Delivery System in Subjects With and Without Prior Lip Augmentation.
Journal of cosmetic dermatology 2025 PMID:41273141

8. J Cosmet Dermatol. 2025 Dec;24(12):e70563. doi: 10.1111/jocd.70563. Efficacy and Tolerability of a Topical Peptide-Hyaluronic Acid Lip Treatment Using a Novel Delivery System in Subjects With and Without Prior Lip Augmentation. Moradi A(1)(2), Jacob C(3)(4), Tao J(5), Love R(6), Osborne S(6),

9.
🧪 RCT
Local delivery of hyaluronan and minocycline as an adjunct to subgingival instrumentation in the treatment of stage II grade B diabetic periodontitis: a randomized split-mouth clinical and microbiological study.
Clinical oral investigations 2025 PMID:41269357

9. Clin Oral Investig. 2025 Nov 21;29(12):578. doi: 10.1007/s00784-025-06664-z. Local delivery of hyaluronan and minocycline as an adjunct to subgingival instrumentation in the treatment of stage II grade B diabetic periodontitis: a randomized split-mouth clinical and microbiological study. ElHa

10.
📄 연구
Autogenous Demineralized Dentin Graft With High Molecular Weight Hyaluronic Acid in Ridge Preservation: Pilot Trial.
Clinical implant dentistry and related research 2025 PMID:41235610

10. Clin Implant Dent Relat Res. 2025 Dec;27(6):e70100. doi: 10.1111/cid.70100. Autogenous Demineralized Dentin Graft With High Molecular Weight Hyaluronic Acid in Ridge Preservation: Pilot Trial. Hesham R(1), Shemais N(1), Saleh HA(2), Fawzy El-Sayed K(1)(3)(4). Author information: (1)Oral Medi

11.
🧪 RCT
Comparative evaluation of clinical and radiographic outcomes of primary molar pulpotomy using hyaluronic acid and mineral trioxide aggregate: A randomized clinical trial.
Journal of the Indian Society of Pedodontics and Preventive Dentistry 2025 PMID:41235565

11. J Indian Soc Pedod Prev Dent. 2025 Oct 1;43(4):567-574. doi: 10.4103/jisppd.jisppd_419_25. Epub 2025 Nov 14. Comparative evaluation of clinical and radiographic outcomes of primary molar pulpotomy using hyaluronic acid and mineral trioxide aggregate: A randomized clinical trial. Lepcha J(1)

12.
🧪 RCT
Comparative evaluation of hyaluronic acid and injectable platelet-rich fibrin in palatal wound healing: a randomized clinical trial.
BMC oral health 2025 PMID:41162972

12. BMC Oral Health. 2025 Oct 29;25(1):1693. doi: 10.1186/s12903-025-07183-9. Comparative evaluation of hyaluronic acid and injectable platelet-rich fibrin in palatal wound healing: a randomized clinical trial. Ceylan Şen S(1), Saraç Atagün Ö(2), Ustaoğlu G(2), Özcan E(2). Author information: (1

13.
🧪 RCT
The effects of applying hyaluronic acid gel after gingival depigmentation using a scalpel or diode laser: a randomized clinical trial.
Quintessence international (Berlin, Germany : 1985) 2025 PMID:41128390

13. Quintessence Int. 2025 Dec 1;56(10):826-838. doi: 10.3290/j.qi.b6646463. The effects of applying hyaluronic acid gel after gingival depigmentation using a scalpel or diode laser: a randomized clinical trial. Fareed SA, Alhabashneh R, Hammad MM, Khader YS, Mansour AI. OBJECTIVE: The aim was t

14.
🧪 RCT
A Multicenter, Randomized, Evaluator-Blind, No-Treatment Controlled Study of YVOIRE Y-Solution 720: A Volumizing Hyaluronic Acid Filler for Midface Volume Deficit.
Aesthetic plastic surgery 2026 PMID:40987843

14. Aesthetic Plast Surg. 2026 Feb;50(3):776-785. doi: 10.1007/s00266-025-05246-4. Epub 2025 Sep 23. A Multicenter, Randomized, Evaluator-Blind, No-Treatment Controlled Study of YVOIRE Y-Solution 720: A Volumizing Hyaluronic Acid Filler for Midface Volume Deficit. Yu N(#)(1), Ting W(#)(1), Xu J

15.
📄 연구
Hyaluronic Acid-Zein Core-Shell Nanoparticles Improve the Anticancer Effect of Curcumin Alone or in Combination with Oxaliplatin against Colorectal Cancer via CD44-Mediated Cellular Uptake.
Molecules (Basel, Switzerland) 2022 PMID:35268597

15. Molecules. 2022 Feb 23;27(5):1498. doi: 10.3390/molecules27051498. Hyaluronic Acid-Zein Core-Shell Nanoparticles Improve the Anticancer Effect of Curcumin Alone or in Combination with Oxaliplatin against Colorectal Cancer via CD44-Mediated Cellular Uptake. Liu L(1)(2)(3), Yang S(2)(3), Chen

16.
📄 연구
Shea Nut Oil Extracts Enhance the Intra-Articular Sodium Hyaluronate Effectiveness on Surgically Induced OA Progression in Rats.
Nutrients 2020 PMID:32235555

2. Nutrients. 2020 Mar 30;12(4):957. doi: 10.3390/nu12040957. Shea Nut Oil Extracts Enhance the Intra-Articular Sodium Hyaluronate Effectiveness on Surgically Induced OA Progression in Rats. Chen IJ(1)(2), Wong CS(1)(3). Author information: (1)Department of Anesthesiology, Cathay General Hospita

17.
📄 연구
The Addition of High Doses of Hyaluronic Acid to a Biphasic Bone Substitute Decreases the Proinflammatory Tissue Response.
International journal of molecular sciences 2019 PMID:31013636

2. Int J Mol Sci. 2019 Apr 22;20(8):1969. doi: 10.3390/ijms20081969. The Addition of High Doses of Hyaluronic Acid to a Biphasic Bone Substitute Decreases the Proinflammatory Tissue Response. Sieger D(1), Korzinskas T(2), Jung O(3), Stojanovic S(4), Wenisch S(5), Smeets R(6)(7), Gosau M(8)(9), S

18.
📄 연구
Synergistic effect of l-ascorbic acid and hyaluronic acid on the expressions of matrix metalloproteinase-3 and -9 in human chondrocytes.
Journal of biomedical materials research. Part B, Applied biomaterials 2018 PMID:28914997

42. J Biomed Mater Res B Appl Biomater. 2018 Jul;106(5):1809-1817. doi: 10.1002/jbm.b.33988. Epub 2017 Sep 15. Synergistic effect of l-ascorbic acid and hyaluronic acid on the expressions of matrix metalloproteinase-3 and -9 in human chondrocytes. Huang TL(1)(2), Yang CH(3), Yanai G(4), Liao JY(

19.
📄 연구
Synergistic Effects of a Mixture of Glycosaminoglycans to Inhibit Adipogenesis and Enhance Chondrocyte Features in Multipotent Cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015 PMID:26584280

8. Cell Physiol Biochem. 2015;37(5):1792-806. doi: 10.1159/000438542. Epub 2015 Nov 13. Synergistic Effects of a Mixture of Glycosaminoglycans to Inhibit Adipogenesis and Enhance Chondrocyte Features in Multipotent Cells. Petrov PD, Granados N, Chetrit C, Martínez-Puig D, Palou A, Bonet ML. BAC

20.
📄 연구
The NSAID dilemma: managing osteoarthritis in high-risk patients.
The Physician and sportsmedicine 2011 PMID:22030942

4. Phys Sportsmed. 2011 Sep;39(3):62-74. doi: 10.3810/psm.2011.09.1922. The NSAID dilemma: managing osteoarthritis in high-risk patients. Roth SH(1), Anderson S. Author information: (1)Arizona Research and Education, Arizona State University, Paradise Valley, AZ, USA. sroth16@cox.net For decade

21.
📄 연구
A role for CD44 in the production of IFN-gamma and immunopathology during infection with Toxoplasma gondii.
Journal of immunology (Baltimore, Md. : 1950) 2001 PMID:11313415

36. J Immunol. 2001 May 1;166(9):5726-32. doi: 10.4049/jimmunol.166.9.5726. A role for CD44 in the production of IFN-gamma and immunopathology during infection with Toxoplasma gondii. Blass SL(1), Puré E, Hunter CA. Author information: (1)Department of Pathobiology, School of Veterinary Medicine

22.
📄 연구
Sulfated glycosaminoglycans and glucosamine may synergize in promoting synovial hyaluronic acid synthesis.
Medical hypotheses 2000 PMID:10859690

20. Med Hypotheses. 2000 May;54(5):798-802. doi: 10.1054/mehy.1999.0954. Sulfated glycosaminoglycans and glucosamine may synergize in promoting synovial hyaluronic acid synthesis. McCarty MF(1), Russell AL, Seed MP. Author information: (1)NutriGuard Research, La Jolla, CA, USA. High-molecular-w

23.
📄 연구
The influence of ethanol on long-term effects of dibutyltin dichloride (DBTC) in pancreas and liver of rats.
Human & experimental toxicology 1998 PMID:9587782

20. Hum Exp Toxicol. 1998 Mar;17(3):144-50. doi: 10.1177/096032719801700304. The influence of ethanol on long-term effects of dibutyltin dichloride (DBTC) in pancreas and liver of rats. Merkord J(1), Weber H, Jonas L, Nizze H, Hennighausen G. Author information: (1)Institute of Pharmacology and

24.
📄 연구
Synergistic effect of alcohol and nicotine on glycosaminoglycan metabolism in rats.
Indian journal of experimental biology 1995 PMID:8714077

8. Indian J Exp Biol. 1995 Dec;33(12):940-2. Synergistic effect of alcohol and nicotine on glycosaminoglycan metabolism in rats. Ashakumary L(1), Vijayammal PL. Author information: (1)Department of Biochemistry, University of Kerala, Trivandrum, India. Oral administration of alcohol along with

25.
📄 연구
A Pilot One and Two-Year Prospective, Blinded Clinical Evaluation of Efficacy, and Safety of Combined Treatment With Crosslinked Hyaluronic Acid Dermal Filler and Barbed Polydioxanone Suspension Threads for Mid-Face Contour Enhancement.
Journal of cosmetic dermatology 2025 PMID:39692727

31. J Cosmet Dermatol. 2025 Feb;24(2):e16700. doi: 10.1111/jocd.16700. Epub 2024 Dec 18. A Pilot One and Two-Year Prospective, Blinded Clinical Evaluation of Efficacy, and Safety of Combined Treatment With Crosslinked Hyaluronic Acid Dermal Filler and Barbed Polydioxanone Suspension Threads for

26.
🧪 RCT
A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis.
Nutrients 2023 PMID:37686801

44. Nutrients. 2023 Aug 29;15(17):3769. doi: 10.3390/nu15173769. A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis. Hill

27.
🧪 RCT
A Two-Center, Prospective, Randomized Controlled Trial to Evaluate the Efficacy and Safety of and Satisfaction with Different Methods of ART FILLER® UNIVERSAL Injection for Correcting Moderate to Severe Nasolabial Folds in Chinese Individuals.
Aesthetic plastic surgery 2023 PMID:36810835

7. Aesthetic Plast Surg. 2023 Aug;47(4):1550-1559. doi: 10.1007/s00266-023-03278-2. Epub 2023 Feb 21. A Two-Center, Prospective, Randomized Controlled Trial to Evaluate the Efficacy and Safety of and Satisfaction with Different Methods of ART FILLER® UNIVERSAL Injection for Correcting Moderate t

28.
📄 연구
DEVELOPMENT OF A MOBILITY ASSESSMENT SCORE FOR EVALUATION OF THE EFFECTS OF ORAL HYALURONIC ACID ON CLINICAL LAMENESS IN ASIAN SMALL-CLAWED OTTERS (AONYX CINEREA) AND AFRICAN SPOT-NECKED OTTERS (HYDRICTIS MACULICOLIS) UNDER HUMAN CARE.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 2022 PMID:35758569

15. J Zoo Wildl Med. 2022 Jun;53(2):275-283. doi: 10.1638/2021-0062. DEVELOPMENT OF A MOBILITY ASSESSMENT SCORE FOR EVALUATION OF THE EFFECTS OF ORAL HYALURONIC ACID ON CLINICAL LAMENESS IN ASIAN SMALL-CLAWED OTTERS (AONYX CINEREA) AND AFRICAN SPOT-NECKED OTTERS (HYDRICTIS MACULICOLIS) UNDER HUMA

29.
📄 연구
Evaluation of Mucosamin Effect on Treating Radiation Induced Oral Mucositis during and after Radiotherapy amongst Patients with Oral Cavity Squamous Cell Carcinoma.
Asian Pacific journal of cancer prevention : APJCP 2021 PMID:34837931

46. Asian Pac J Cancer Prev. 2021 Nov 1;22(11):3711-3715. doi: 10.31557/APJCP.2021.22.11.3711. Evaluation of Mucosamin Effect on Treating Radiation Induced Oral Mucositis during and after Radiotherapy amongst Patients with Oral Cavity Squamous Cell Carcinoma. Nasrollahi H(1), Khaki S(1), Ansari

30.
🧪 RCT
Intra-Articular Injections in Patients with Femoroacetabular Impingement: a Prospective, Randomized, Double-blind, Cross-over Study.
Journal of Korean medical science 2016 PMID:27709863

30. J Korean Med Sci. 2016 Nov;31(11):1822-1827. doi: 10.3346/jkms.2016.31.11.1822. Intra-Articular Injections in Patients with Femoroacetabular Impingement: a Prospective, Randomized, Double-blind, Cross-over Study. Lee YK(1), Lee GY(2)(3), Lee JW(2), Lee E(2), Kang HS(2). Author information: (

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