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Antioxidant and anti-inflammatory effects of ginger supplementation in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomised controlled trials.

1. Inflammopharmacology. 2025 Dec;33(12):7197-7216. doi: 10.1007/s10787-025-01994-6. Epub 2025 Oct 22. Antioxidant and anti-inflammatory effects of ginger supplementation in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomised controlled trials. Rjabi S(1), B

Effect of ginger (Zingiber officinale) intake on human serum lipid profile: Systematic review and meta-analysis.

2. Phytother Res. 2023 Jun;37(6):2472-2483. doi: 10.1002/ptr.7769. Epub 2023 Feb 14. Effect of ginger (Zingiber officinale) intake on human serum lipid profile: Systematic review and meta-analysis. Salih AK(1), Alwan AH(2), Khadim M(3), Al-Qaim ZH(4), Mardanov B(5), El-Sehrwy AA(6), Ahmed YI(7)

The Effect of Ginger (Zingiber officinale) on Improving Blood Lipids and Body Weight; A Systematic Review and Multivariate Meta-analysis of Clinical Trials.

3. Curr Pharm Des. 2022;28(35):2920-2943. doi: 10.2174/1381612828666220926093847. The Effect of Ginger (Zingiber officinale) on Improving Blood Lipids and Body Weight; A Systematic Review and Multivariate Meta-analysis of Clinical Trials. Asghari-Jafarabadi M(1)(2)(3), Khalili L(4). Author infor

Effect of ginger (Zingiber officinale) supplementation on oxidative stress parameters: A systematic review and meta-analysis.

4. J Food Biochem. 2021 Feb;45(2):e13612. doi: 10.1111/jfbc.13612. Epub 2021 Jan 17. Effect of ginger (Zingiber officinale) supplementation on oxidative stress parameters: A systematic review and meta-analysis. Morvaridzadeh M(1), Sadeghi E(2), Agah S(3), Fazelian S(4), Rahimlou M(5), Kern FG(6

Effect of ginger (Zingiber officinale) on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.

5. Cytokine. 2020 Nov;135:155224. doi: 10.1016/j.cyto.2020.155224. Epub 2020 Aug 5. Effect of ginger (Zingiber officinale) on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials. Morvaridzadeh M(1), Fazelian S(2), Agah S(3), Khazdouz M(4), Rahimlou M(5), Ag

Efficacy of Ginger (Zingiber officinale) in Ameliorating Chemotherapy-Induced Nausea and Vomiting and Chemotherapy-Related Outcomes: A Systematic Review Update and Meta-Analysis.

6. J Acad Nutr Diet. 2019 Dec;119(12):2055-2068. doi: 10.1016/j.jand.2019.06.009. Epub 2019 Sep 10. Efficacy of Ginger (Zingiber officinale) in Ameliorating Chemotherapy-Induced Nausea and Vomiting and Chemotherapy-Related Outcomes: A Systematic Review Update and Meta-Analysis. Crichton M, Mars

Dietary ginger as a traditional therapy for blood sugar control in patients with type 2 diabetes mellitus: A systematic review and meta-analysis.

7. Medicine (Baltimore). 2019 Mar;98(13):e15054. doi: 10.1097/MD.0000000000015054. Dietary ginger as a traditional therapy for blood sugar control in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Huang FY(1), Deng T, Meng LX, Ma XL. Author information: (1)Youjian

Dietary supplements for dysmenorrhoea.

8. Cochrane Database Syst Rev. 2016 Mar 22;3(3):CD002124. doi: 10.1002/14651858.CD002124.pub2. Dietary supplements for dysmenorrhoea. Pattanittum P(1), Kunyanone N, Brown J, Sangkomkamhang US, Barnes J, Seyfoddin V, Marjoribanks J. Author information: (1)Department of Biostatistics and Demograp

Effect of aromatherapy with peppermint, ginger, and lavender on postoperative nausea severity after oral surgery under general anaesthesia: A single-blind randomized controlled trial.

9. Complement Ther Med. 2025 Jun;90:103169. doi: 10.1016/j.ctim.2025.103169. Epub 2025 Mar 26. Effect of aromatherapy with peppermint, ginger, and lavender on postoperative nausea severity after oral surgery under general anaesthesia: A single-blind randomized controlled trial. Ishikawa E(1), F

The efficacy and safety of ginger (Zingiber officinale) rhizome extract in outpatients with COVID-19: A randomized double-blind placebo-control clinical trial.

10. Medicine (Baltimore). 2024 May 31;103(22):e38289. doi: 10.1097/MD.0000000000038289. The efficacy and safety of ginger (Zingiber officinale) rhizome extract in outpatients with COVID-19: A randomized double-blind placebo-control clinical trial. Ameri A(1), Farashahinejad M(2), Davoodian P(2)

The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial.

11. Nutrients. 2024 May 29;16(11):1685. doi: 10.3390/nu16111685. The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial. Al Dhaheri AS(1), Alkhatib DH(1), Feehan J(2), Cheikh Ismail L(3)(4), Apostolopoulos V(2)(5), Stojanovska L(1)(2). Author inf

The Effects of Ginger (Zingiber Officinale Roscoe) on Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blinded Placebo-Controlled Clinical Trial.

12. J Diet Suppl. 2024;21(3):294-312. doi: 10.1080/19390211.2023.2263788. Epub 2023 Oct 11. The Effects of Ginger (Zingiber Officinale Roscoe) on Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blinded Placebo-Controlled Clinical Trial. Ghoreishi

Effect of Ginger Root Powder on Gastrointestinal Bacteria Composition, Gastrointestinal Symptoms, Mental Health, Fatigue, and Quality of Life: A Double-Blind Placebo-Controlled Trial.

13. J Nutr. 2023 Nov;153(11):3193-3206. doi: 10.1016/j.tjnut.2023.09.002. Epub 2023 Sep 9. Effect of Ginger Root Powder on Gastrointestinal Bacteria Composition, Gastrointestinal Symptoms, Mental Health, Fatigue, and Quality of Life: A Double-Blind Placebo-Controlled Trial. Crichton M(1), Marsh

The effect of ginger (Zingiber officinale) supplementation on clinical, biochemical, and anthropometric parameters in patients with multiple sclerosis: a double-blind randomized controlled trial.

14. Food Funct. 2023 Apr 24;14(8):3701-3711. doi: 10.1039/d3fo00167a. The effect of ginger (Zingiber officinale) supplementation on clinical, biochemical, and anthropometric parameters in patients with multiple sclerosis: a double-blind randomized controlled trial. Foshati S(1), Poursadeghfard M

Ginger supplementation does not increase energy expenditure in female adults.

15. Nutrition. 2022 Nov-Dec;103-104:111803. doi: 10.1016/j.nut.2022.111803. Epub 2022 Jul 25. Ginger supplementation does not increase energy expenditure in female adults. Braga Tibaes JR(1), Martins LB(2), Rodrigues AMDS(3), Amaral MHA(3), Teixeira AL(4), Ferreira AVM(3). Author information: (

Ginger as a Modulator of Drug Metabolizing Enzymes and Transporters: Potential Implications for Herb-Drug Interactions.

36. J Diet Suppl. 2026;23(2):240-256. doi: 10.1080/19390211.2025.2606752. Epub 2025 Dec 28. Ginger as a Modulator of Drug Metabolizing Enzymes and Transporters: Potential Implications for Herb-Drug Interactions. Husain I(1), Idrisi M(1), Kotwal P(1), Khan IA(1)(2), Khan SI(1)(2). Author informa

Bactericidal action of ginger (Zingiber officinale Roscoe) extract against Escherichia coli through synergistic modulation of the AcrAB-TolC efflux pump and inhibition of peptidoglycan synthesis: In vitro and in silico approaches.

36. Microb Pathog. 2025 Jul;204:107624. doi: 10.1016/j.micpath.2025.107624. Epub 2025 Apr 21. Bactericidal action of ginger (Zingiber officinale Roscoe) extract against Escherichia coli through synergistic modulation of the AcrAB-TolC efflux pump and inhibition of peptidoglycan synthesis: In vit

Antimicrobial Importance of Medicinal Plants in Nigeria.

45. ScientificWorldJournal. 2020 Sep 22;2020:7059323. doi: 10.1155/2020/7059323. eCollection 2020. Antimicrobial Importance of Medicinal Plants in Nigeria. Ugboko HU(1)(2), Nwinyi OC(1)(2), Oranusi SU(1)(2), Fatoki TH(3), Omonhinmin CA(2)(4). Author information: (1)Microbiology Unit, Department

Assessing the Efficacy of Broad-Spectrum Antibiotics in Controlling Bacterial Contamination in the In Vitro Micropropagation of Ginger (Zingiber officinale Rosc).

5. ScientificWorldJournal. 2020 Jun 13;2020:6431301. doi: 10.1155/2020/6431301. eCollection 2020. Assessing the Efficacy of Broad-Spectrum Antibiotics in Controlling Bacterial Contamination in the In Vitro Micropropagation of Ginger (Zingiber officinale Rosc). Tewelde S(1), Patharajan S(2), Tek

Phytochemicals, antioxidant activity and hepatoprotective effect of ginger (Zingiber officinale) on diethylnitrosamine toxicity in rats.

42. Biomarkers. 2019 Jul;24(5):436-447. doi: 10.1080/1354750X.2019.1606280. Epub 2019 May 7. Phytochemicals, antioxidant activity and hepatoprotective effect of ginger (Zingiber officinale) on diethylnitrosamine toxicity in rats. Fahmi A(1), Hassanen N(2), Abdur-Rahman M(1), Shams-Eldin E(2). A

Safety of herbal medicine use during chemotherapy in patients with ovarian cancer: a "bedside-to-bench" approach.

27. Med Oncol. 2017 Apr;34(4):54. doi: 10.1007/s12032-017-0910-9. Epub 2017 Feb 25. Safety of herbal medicine use during chemotherapy in patients with ovarian cancer: a "bedside-to-bench" approach. Ben-Arye E(1)(2), Lavie O(3), Samuels N(4)(5), Khamaisie H(6), Schiff E(7), Raz OG(4), Mahajna J(6

6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress.

6. PLoS One. 2012;7(6):e39664. doi: 10.1371/journal.pone.0039664. Epub 2012 Jun 29. 6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress. Hu R(1), Zhou P, Peng YB, Xu X, Ma J, Liu Q, Zhang L, Wen XD, Qi L

Herb-drug interactions and mechanistic and clinical considerations.

11. Curr Drug Metab. 2012 Jun 1;13(5):640-51. doi: 10.2174/1389200211209050640. Herb-drug interactions and mechanistic and clinical considerations. Chen XW(1), Sneed KB, Pan SY, Cao C, Kanwar JR, Chew H, Zhou SF. Author information: (1)Department of General Surgery, the First People’s Hospital of

Clinical herbal interactions with conventional drugs: from molecules to maladies.

24. Curr Med Chem. 2011;18(31):4836-50. doi: 10.2174/092986711797535317. Clinical herbal interactions with conventional drugs: from molecules to maladies. Chen XW(1), Serag ES, Sneed KB, Liang J, Chew H, Pan SY, Zhou SF. Author information: (1)Department of General Surgery, Shunde First People’s

Ginger (Zingiber officinale Roscoe) elicits antinociceptive properties and potentiates morphine-induced analgesia in the rat radiant heat tail-flick test.

41. J Med Food. 2010 Dec;13(6):1397-401. doi: 10.1089/jmf.2010.1043. Ginger (Zingiber officinale Roscoe) elicits antinociceptive properties and potentiates morphine-induced analgesia in the rat radiant heat tail-flick test. Sepahvand R(1), Esmaeili-Mahani S, Arzi A, Rasoulian B, Abbasnejad M. Au

Ginger (Zingiber Officinale) Supplementation and Biomarkers of Cardiovascular Disease - A Systematic Review.

30. J Diet Suppl. 2026;23(1):118-149. doi: 10.1080/19390211.2025.2583512. Epub 2025 Nov 6. Ginger (Zingiber Officinale) Supplementation and Biomarkers of Cardiovascular Disease - A Systematic Review. Rjabi S(1), Dabirian N(2), Amani-Beni R(3), Taghavi M(4), Askarpour M(5). Author information: (

Zingerone as a Neuroprotective Agent Against Cognitive Disorders: A Systematic Review of Preclinical Studies.

46. Int J Mol Sci. 2025 Jun 25;26(13):6111. doi: 10.3390/ijms26136111. Zingerone as a Neuroprotective Agent Against Cognitive Disorders: A Systematic Review of Preclinical Studies. Olasehinde TA(1)(2), Olaokun OO(3). Author information: (1)Nutrition and Toxicology Division, Food Technology Depar

Therapeutic effects and mechanisms of action of ginger and its bioactive components on inflammatory response, oxidative stress, the immune system, and organ failure in sepsis: a comprehensive systematic review.

6. Nutr Rev. 2024 Dec 1;82(12):1800-1819. doi: 10.1093/nutrit/nuad156. Therapeutic effects and mechanisms of action of ginger and its bioactive components on inflammatory response, oxidative stress, the immune system, and organ failure in sepsis: a comprehensive systematic review. Velayati A(1),

Zingiber officinale: A Systematic Review of Botany, Phytochemistry and Pharmacology of Gut Microbiota-Related Gastrointestinal Benefits.

36. Am J Chin Med. 2022;50(4):1007-1042. doi: 10.1142/S0192415X22500410. Zingiber officinale: A Systematic Review of Botany, Phytochemistry and Pharmacology of Gut Microbiota-Related Gastrointestinal Benefits. Lai W(1), Yang S(1), Lin X(1), Zhang X(1), Huang Y(1), Zhou J(1), Fu C(1), Li R(1), Zh

Ginger: a systematic review of clinical trials and recent advances in encapsulation of its bioactive compounds.

10. Food Funct. 2022 Feb 7;13(3):1078-1091. doi: 10.1039/d1fo02998c. Ginger: a systematic review of clinical trials and recent advances in encapsulation of its bioactive compounds. Tavares L(1), Smaoui S(2), Pinilla CMB(1), Ben Hlima H(3), Lopes Barros H(4). Author information: (1)Institute of F