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아마씨유

Flaxseed Oil

📑 PubMed 30편 🐟 오메가 🗓️ 최신 2025
🔬 메타분석 10 📋 체계적 리뷰 2 🧪 RCT 6

📖 핵심 요약

📖 30편 · 15분 읽기

아마씨유은(는) 오메가 계열 보충제입니다. 주로 항염, 혈압, 체중 관리, 뇌 건강 분야에서 연구되었으며, PubMed에 30편의 관련 논문이 있습니다.

🔍 연구 분야별 근거

항염 논문 2편
혈압 논문 2편
체중 관리 논문 2편
뇌 건강 논문 1편

* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)

📊 효과 크기 분포 (Forest plot)

각 연구의 효과 추정치와 95% 신뢰구간. 개별 연구를 통합(pooling)하지 않고 그대로 표시합니다.

39558500-0.47 (-1.76–0.8)38992480-0.63 (-1–-0.27)35859037-3.86 (-7.59–-0.13)33183549-0.22 (-0.43–-0.01)31115436-0.38 (-1.19–-0.3)38726572-85.78 (-155.24–-16.32)-1.8e+02024MD (favours ← / →)

📚 관련 논문 (30편) · 📊 정량 근거 10건

1.
🔬 메타분석
Supplementation of Olive Oil and Flaxseed Oil on Blood Pressure and Inflammation in Healthy and At-Risk Adults: A Systematic Literature Review and Meta-Analysis.
Current hypertension reviews 2024 PMID:39558500
📊 MD -0.47 (95% CI -1.76–0.8) · n=17

1. Curr Hypertens Rev. 2024;20(3):141-155. doi: 10.2174/0115734021337760241104063418. Supplementation of Olive Oil and Flaxseed Oil on Blood Pressure and Inflammation in Healthy and At-Risk Adults: A Systematic Literature Review and Meta-Analysis. McNabb TB(1), Young I(2), Newman RG(3), Skinner

2.
🔬 메타분석
The effects of flaxseed (Linum usitatissimum) supplementation on anthropometric indices: An updated systematic review and meta-analysis of randomized clinical trials.
Complementary therapies in medicine 2024 PMID:38992480
📊 MD -0.63 (95% CI -1–-0.27)

2. Complement Ther Med. 2024 Sep;84:103066. doi: 10.1016/j.ctim.2024.103066. Epub 2024 Jul 9. The effects of flaxseed (Linum usitatissimum) supplementation on anthropometric indices: An updated systematic review and meta-analysis of randomized clinical trials. Musazadeh V(1), Abolghasemian M(2)

3.
🔬 메타분석
Effect of Alpha-Linolenic Acid Supplementation on Cardiovascular Disease Risk Profile in Individuals with Obesity or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Advances in nutrition (Bethesda, Md.) 2023 PMID:37778442
📊 SMD -0.45 (95% CI -0.73–-0.17) · n=1183

3. Adv Nutr. 2023 Nov;14(6):1644-1655. doi: 10.1016/j.advnut.2023.09.010. Epub 2023 Sep 29. Effect of Alpha-Linolenic Acid Supplementation on Cardiovascular Disease Risk Profile in Individuals with Obesity or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Yin

4.
🔬 메타분석
A systematic review and meta-analysis of the omega-3 fatty acids effects on brain-derived neurotrophic factor (BDNF).
Nutritional neuroscience 2024 PMID:37589276
📊 SMD 0.72 (95% CI 0.28–1.15) · n=587

4. Nutr Neurosci. 2024 Jul;27(7):715-725. doi: 10.1080/1028415X.2023.2245996. Epub 2023 Aug 17. A systematic review and meta-analysis of the omega-3 fatty acids effects on brain-derived neurotrophic factor (BDNF). Ziaei S(1), Mohammadi S(2), Hasani M(3), Morvaridi M(4), Belančić A(5)(6), Danesh

5.
🔬 메타분석
The effect of flaxseed oil consumtion on blood pressure among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized clinical trials.
Phytotherapy research : PTR 2022 PMID:35859037
📊 MD -3.86 (95% CI -7.59–-0.13)

5. Phytother Res. 2022 Oct;36(10):3766-3773. doi: 10.1002/ptr.7566. Epub 2022 Jul 20. The effect of flaxseed oil consumtion on blood pressure among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized clinical trials. Mahmudiono T(1), Jasim

6.
🔬 메타분석
Effects of flaxseed oil supplementation on biomarkers of inflammation and oxidative stress in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials.
Clinical nutrition ESPEN 2020 PMID:33183549
📊 MD -0.22 (95% CI -0.43–-0.01)

6. Clin Nutr ESPEN. 2020 Dec;40:27-33. doi: 10.1016/j.clnesp.2020.09.017. Epub 2020 Oct 16. Effects of flaxseed oil supplementation on biomarkers of inflammation and oxidative stress in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized co

7.
📄 연구
Nutritional interventions for treating foot ulcers in people with diabetes.
The Cochrane database of systematic reviews 2020 PMID:32677037
📊 RR 1.09 (95% CI 0.85–1.4) · n=629

7. Cochrane Database Syst Rev. 2020 Jul 17;7(7):CD011378. doi: 10.1002/14651858.CD011378.pub2. Nutritional interventions for treating foot ulcers in people with diabetes. Moore ZE(1), Corcoran MA(2), Patton D(1). Author information: (1)School of Nursing & Midwifery, Royal College of Surgeons in

8.
🔬 메타분석
Effects of Flaxseed Interventions on Circulating Inflammatory Biomarkers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Advances in nutrition (Bethesda, Md.) 2019 PMID:31115436
📊 MD -0.38 (95% CI -1.19–-0.3)

8. Adv Nutr. 2019 Nov 1;10(6):1108-1119. doi: 10.1093/advances/nmz048. Effects of Flaxseed Interventions on Circulating Inflammatory Biomarkers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Rahimlou M(1)(2), Jahromi NB(1)(2), Hasanyani N(3), Ahmadi AR(1)(4). Author info

9.
🔬 메타분석
Flaxseed supplementation on glucose control and insulin sensitivity: a systematic review and meta-analysis of 25 randomized, placebo-controlled trials.
Nutrition reviews 2018 PMID:29228348

9. Nutr Rev. 2018 Feb 1;76(2):125-139. doi: 10.1093/nutrit/nux052. Flaxseed supplementation on glucose control and insulin sensitivity: a systematic review and meta-analysis of 25 randomized, placebo-controlled trials. Mohammadi-Sartang M(1), Sohrabi Z(2), Barati-Boldaji R(2), Raeisi-Dehkordi H(1

10.
🔬 메타분석
Meta-analysis of the effects of flaxseed interventions on blood lipids.
The American journal of clinical nutrition 2009 PMID:19515737

10. Am J Clin Nutr. 2009 Aug;90(2):288-97. doi: 10.3945/ajcn.2009.27469. Epub 2009 Jun 10. Meta-analysis of the effects of flaxseed interventions on blood lipids. Pan A(1), Yu D, Demark-Wahnefried W, Franco OH, Lin X. Author information: (1)Key Laboratory of Nutrition and Metabolism, Institute f

11.
📄 연구
Thus far there are no statistically significant differences between various apolipoprotein E genotypes in the cluster of seven responsiveness to a flaxseed oil supplement in persons with type 2 diabetes.
Endocrine regulations 2025 PMID:40958692

11. Endocr Regul. 2025 Sep 5;59(1):141-146. doi: 10.2478/enr-2025-0016. Print 2025 Jan 1. Thus far there are no statistically significant differences between various apolipoprotein E genotypes in the cluster of seven responsiveness to a flaxseed oil supplement in persons with type 2 diabetes. B

12.
📄 연구
Clinical application of hempseed or flaxseed oil-based lyotropic liquid crystals: Evaluation of their impact on skin barrier function.
Acta pharmaceutica (Zagreb, Croatia) 2024 PMID:38815204

12. Acta Pharm. 2024 May 30;74(2):301-313. doi: 10.2478/acph-2024-0014. Print 2024 Jun 1. Clinical application of hempseed or flaxseed oil-based lyotropic liquid crystals: Evaluation of their impact on skin barrier function. Vitek M(1), Matjaž MG(1). Author information: (1)1University of Ljublj

13.
🧪 RCT
Effects of flaxseed oil supplementation on metaphase II oocyte rates in IVF cycles with decreased ovarian reserve: a randomized controlled trial.
Frontiers in endocrinology 2024 PMID:38469148
📊 OR 1 (95% CI 1–1) · n=108

13. Front Endocrinol (Lausanne). 2024 Feb 26;15:1280760. doi: 10.3389/fendo.2024.1280760. eCollection 2024. Effects of flaxseed oil supplementation on metaphase II oocyte rates in IVF cycles with decreased ovarian reserve: a randomized controlled trial. Chu Q(1), Yu YX(1), Zhang JZ(1), Zhang YT(

14.
📄 연구
Supplementation with Flaxseed Oil Rich in Alpha-Linolenic Acid Improves Verbal Fluency in Healthy Older Adults.
Nutrients 2023 PMID:36986229

14. Nutrients. 2023 Mar 21;15(6):1499. doi: 10.3390/nu15061499. Supplementation with Flaxseed Oil Rich in Alpha-Linolenic Acid Improves Verbal Fluency in Healthy Older Adults. Ogawa T(1)(2), Sawane K(3), Ookoshi K(3), Kawashima R(1)(2). Author information: (1)Department of Advanced Brain Science

15.
📄 연구
Fatty acid correlations with HOMA-IR and HOMA-% β are differentially dictated by their serum free and total pools and flaxseed oil supplementation.
Endocrine regulations 2023 PMID:36753666

15. Endocr Regul. 2023 Feb 8;57(1):18-24. doi: 10.2478/enr-2023-0003. Print 2023 Jan 1. Fatty acid correlations with HOMA-IR and HOMA-% β are differentially dictated by their serum free and total pools and flaxseed oil supplementation. Barre DE(1), Mizier-Barre KA(2), Griscti O(3), Hafez K(4).

16.
🧪 RCT
Clinical Assessment of Efficacy of Omega 3 in Oral Submucous Fibrosis Patients - A Randomized Controlled Trial.
Asian Pacific journal of cancer prevention : APJCP 2022 PMID:35485674

36. Asian Pac J Cancer Prev. 2022 Apr 1;23(4):1185-1192. doi: 10.31557/APJCP.2022.23.4.1185. Clinical Assessment of Efficacy of Omega 3 in Oral Submucous Fibrosis Patients - A Randomized Controlled Trial. Raizada MK(1), Sable DM(2). Author information: (1)National Centre for cell science, Lab N

17.
🧪 RCT
Dietary Fat Chain Length, Saturation, and PUFA Source Acutely Affect Diet-Induced Thermogenesis but Not Satiety in Adults in a Randomized, Crossover Trial.
Nutrients 2021 PMID:34444773

39. Nutrients. 2021 Jul 29;13(8):2615. doi: 10.3390/nu13082615. Dietary Fat Chain Length, Saturation, and PUFA Source Acutely Affect Diet-Induced Thermogenesis but Not Satiety in Adults in a Randomized, Crossover Trial. Rust BM(1), Raatz SK(1)(2)(3), Casperson SL(1)(2), Duke SE(4), Picklo MJ(1)(

18.
📄 연구
Oils Rich in α-Linolenic Acid or Docosahexaenoic Acid Have Distinct Effects on Plasma Oxylipin and Adiponectin Concentrations and on Monocyte Bioenergetics in Women with Obesity.
The Journal of nutrition 2021 PMID:34293124

12. J Nutr. 2021 Oct 1;151(10):3053-3066. doi: 10.1093/jn/nxab235. Oils Rich in α-Linolenic Acid or Docosahexaenoic Acid Have Distinct Effects on Plasma Oxylipin and Adiponectin Concentrations and on Monocyte Bioenergetics in Women with Obesity. Pauls SD(1)(2), Rodway LR(2)(3), Sidhu KK(1)(2), W

19.
📄 연구
Application of Cryopreserved Human Intestinal Mucosa and Cryopreserved Human Enterocytes in the Evaluation of Herb-Drug Interactions: Evaluation of CYP3A Inhibitory Potential of Grapefruit Juice and Commercial Formulations of Twenty-Nine Herbal Supplements.
Drug metabolism and disposition: the biological fate of chemicals 2020 PMID:32719085

5. Drug Metab Dispos. 2020 Oct;48(10):1084-1091. doi: 10.1124/dmd.120.000033. Epub 2020 Jul 27. Application of Cryopreserved Human Intestinal Mucosa and Cryopreserved Human Enterocytes in the Evaluation of Herb-Drug Interactions: Evaluation of CYP3A Inhibitory Potential of Grapefruit Juice and C

20.
📄 연구
Combining doxorubicin with a phenolic extract from flaxseed oil: Evaluation of the effect on two breast cancer cell lines.
International journal of oncology 2017 PMID:28101573

28. Int J Oncol. 2017 Feb;50(2):468-476. doi: 10.3892/ijo.2017.3835. Epub 2017 Jan 2. Combining doxorubicin with a phenolic extract from flaxseed oil: Evaluation of the effect on two breast cancer cell lines. Guerriero E(1), Sorice A(1), Capone F(1), Storti G(2), Colonna G(3), Ciliberto G(4), C

21.
🧪 RCT
A randomized-controlled clinical trial investigating the effect of omega-3 fatty acids and vitamin E co-supplementation on markers of insulin metabolism and lipid profiles in gestational diabetes.
Journal of clinical lipidology 2016 PMID:27055970

29. J Clin Lipidol. 2016 Mar-Apr;10(2):386-93. doi: 10.1016/j.jacl.2015.12.017. Epub 2015 Dec 29. A randomized-controlled clinical trial investigating the effect of omega-3 fatty acids and vitamin E co-supplementation on markers of insulin metabolism and lipid profiles in gestational diabetes.

22.
📄 연구
Flaxseed oil enhances the effectiveness of trastuzumab in reducing the growth of HER2-overexpressing human breast tumors (BT-474).
The Journal of nutritional biochemistry 2015 PMID:25441844

49. J Nutr Biochem. 2015 Jan;26(1):16-23. doi: 10.1016/j.jnutbio.2014.08.001. Epub 2014 Sep 22. Flaxseed oil enhances the effectiveness of trastuzumab in reducing the growth of HER2-overexpressing human breast tumors (BT-474). Mason JK(1), Fu M(1), Chen J(1), Thompson LU(2). Author information:

23.
📄 연구
Flaxseed and its lignan and oil components: can they play a role in reducing the risk of and improving the treatment of breast cancer?
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2014 PMID:24869971

8. Appl Physiol Nutr Metab. 2014 Jun;39(6):663-78. doi: 10.1139/apnm-2013-0420. Epub 2013 Dec 23. Flaxseed and its lignan and oil components: can they play a role in reducing the risk of and improving the treatment of breast cancer? Mason JK(1), Thompson LU. Author information: (1)Department of

24.
📄 연구
Flax and flaxseed oil (Linum usitatissimum): a review by the Natural Standard Research Collaboration.
Journal of the Society for Integrative Oncology 2007 PMID:17761128

24. J Soc Integr Oncol. 2007 Summer;5(3):92-105. doi: 10.2310/7200.2007.005. Flax and flaxseed oil (Linum usitatissimum): a review by the Natural Standard Research Collaboration. Basch E(1), Bent S, Collins J, Dacey C, Hammerness P, Harrison M, Smith M, Szapary P, Ulbricht C, Vora M, Weissner W;

25.
📄 연구
Increasing trends in elderly persons' use of nonvitamin, nonmineral dietary supplements and concurrent use of medications.
Journal of the American Dietetic Association 2005 PMID:15635346

23. J Am Diet Assoc. 2005 Jan;105(1):54-63. doi: 10.1016/j.jada.2004.11.002. Increasing trends in elderly persons' use of nonvitamin, nonmineral dietary supplements and concurrent use of medications. Wold RS(1), Lopez ST, Yau CL, Butler LM, Pareo-Tubbeh SL, Waters DL, Garry PJ, Baumgartner RN.

26.
🧪 RCT
Serum metabolomics profiles in response to n-3 fatty acids in Chinese patients with type 2 diabetes: a double-blind randomised controlled trial.
Scientific reports 2016 PMID:27404516

14. Sci Rep. 2016 Jul 12;6:29522. doi: 10.1038/srep29522. Serum metabolomics profiles in response to n-3 fatty acids in Chinese patients with type 2 diabetes: a double-blind randomised controlled trial. Zheng JS(1)(2), Lin M(3), Imamura F(2), Cai W(1), Wang L(4), Feng JP(3), Ruan Y(5)(6), Tang J

27.
🧪 RCT
Effects of n-3 fatty acid supplements on glycemic traits in Chinese type 2 diabetic patients: A double-blind randomized controlled trial.
Molecular nutrition & food research 2016 PMID:27279274

30. Mol Nutr Food Res. 2016 Oct;60(10):2176-2184. doi: 10.1002/mnfr.201600230. Epub 2016 Jul 12. Effects of n-3 fatty acid supplements on glycemic traits in Chinese type 2 diabetic patients: A double-blind randomized controlled trial. Zheng JS(1)(2), Lin M(3), Fang L(4), Yu Y(5), Yuan L(5), Jin

28.
📋 체계적 리뷰
Systematic Review of the Effects of Plant-Based Foods on Metabolic Outcomes in Adults with MASLD and Comorbidities Such as Obesity, Metabolic Syndrome, and Type 2 Diabetes.
Nutrients 2025 PMID:41010543

42. Nutrients. 2025 Sep 22;17(18):3020. doi: 10.3390/nu17183020. Systematic Review of the Effects of Plant-Based Foods on Metabolic Outcomes in Adults with MASLD and Comorbidities Such as Obesity, Metabolic Syndrome, and Type 2 Diabetes. Jurek JM(1), Zablocka-Slowinska K(2), Pieczynska J(3), Cla

29.
🔬 메타분석
The impact of flaxseed oil on lipid profiles, weight loss, and inflammatory markers in hemodialysis patients: A systematic review and meta-analysis of randomized controlled trials.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2024 PMID:38726572
📊 MD -85.78 (95% CI -155.24–-16.32)

50. Ther Apher Dial. 2024 Aug;28(4):534-546. doi: 10.1111/1744-9987.14140. Epub 2024 May 10. The impact of flaxseed oil on lipid profiles, weight loss, and inflammatory markers in hemodialysis patients: A systematic review and meta-analysis of randomized controlled trials. Tabrizi R(1)(2), Aziz

30.
📋 체계적 리뷰
Effect of Fish-Based Diet on Malnourished Children: A Systematic Review.
Iranian journal of medical sciences 2024 PMID:38584649

18. Iran J Med Sci. 2024 Mar 1;49(3):137-146. doi: 10.30476/ijms.2023.96986.2863. eCollection 2024 Mar. Effect of Fish-Based Diet on Malnourished Children: A Systematic Review. La Banudi B(1), Leksono P(1), Anasiru MA(2). Author information: (1)Mother and Child Nutrition, Department of Nutrition

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