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DGL 감초 (속쓰림)

DGL Licorice (Heartburn)

📑 PubMed 30편 🫄 소화 🗓️ 최신 2026
🔬 메타분석 10 🧪 RCT 7

📖 핵심 요약

📖 30편 · 15분 읽기

DGL 감초 (속쓰림)은(는) 소화 계열 보충제입니다. PubMed에 30편의 관련 논문이 있습니다.

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혈압약 전반 ⚠️ 보통

영향: 혈압 상승 + 저칼륨혈증

대처: 감초 성분 보충제 장기 복용 금지 (2주 이상)

📊 효과 크기 분포 (Forest plot)

각 연구의 효과 추정치와 95% 신뢰구간. 개별 연구를 통합(pooling)하지 않고 그대로 표시합니다.

415743481.06 (1.01–1.11)415248302.29 (1.36–3.87)414376950.69420068601.01 (0.98–1.05)0.215RR (favours ← / →)

📚 관련 논문 (30편) · 📊 정량 근거 7건

1.
🔬 메타분석
Difference in the risk of gastrointestinal manifestations between peritoneal and hemodialysis patients: a systematic review and meta-analysis.
PeerJ 2026 PMID:42004711

1. PeerJ. 2026 Apr 14;14:e21090. doi: 10.7717/peerj.21090. eCollection 2026. Difference in the risk of gastrointestinal manifestations between peritoneal and hemodialysis patients: a systematic review and meta-analysis. Li J(1), Liang J(2), Shi X(2), Lu W(3). Author information: (1)Nephrology De

2.
🔬 메타분석
Efficacy and safety of probiotics combined with bismuth-containing quadruple therapy for Helicobacter pylori eradication: a systematic review and meta-analysis.
Frontiers in microbiology 2025 PMID:41574348
📊 RR 1.06 (95% CI 1.01–1.11) · n=630

2. Front Microbiol. 2026 Jan 7;16:1704508. doi: 10.3389/fmicb.2025.1704508. eCollection 2025. Efficacy and safety of probiotics combined with bismuth-containing quadruple therapy for Helicobacter pylori eradication: a systematic review and meta-analysis. Zhou S(#)(1)(2), Yu Y(#)(2), Tian J(1)(2

3.
🔬 메타분석
A systematic review and meta-analysis of randomized controlled trials: the effect of potassium-competitive acid blockers on nighttime symptoms of gastroesophageal reflux disease.
Esophagus : official journal of the Japan Esophageal Society 2026 PMID:41524830
📊 RR 2.29 (95% CI 1.36–3.87)

3. Esophagus. 2026 Apr;23(2):275-291. doi: 10.1007/s10388-025-01181-0. Epub 2026 Jan 12. A systematic review and meta-analysis of randomized controlled trials: the effect of potassium-competitive acid blockers on nighttime symptoms of gastroesophageal reflux disease. Koo TH(1)(2)(3), Fass R(4).

4.
📄 연구
Efficacy, safety and cost-effectiveness of potassium-competitive acid blockers versus proton pump inhibitors in gastroesophageal reflux disease.
Scandinavian journal of gastroenterology 2026 PMID:41437695
📊 RR 0.69 · n=5133

4. Scand J Gastroenterol. 2026 Feb;61(2):241-256. doi: 10.1080/00365521.2025.2603613. Epub 2025 Dec 23. Efficacy, safety and cost-effectiveness of potassium-competitive acid blockers versus proton pump inhibitors in gastroesophageal reflux disease. Li F(1), Tan J(1), Qin L(1). Author informatio

5.
🔬 메타분석
Long-term (>10 Years) Outcomes of Laparoscopic Nissen Fundoplication: A Systematic Review and Meta-Analysis.
Annals of surgery 2026 PMID:41408543

5. Ann Surg. 2026 Apr 1;283(4):539-545. doi: 10.1097/SLA.0000000000007000. Epub 2025 Dec 18. Long-term (>10 Years) Outcomes of Laparoscopic Nissen Fundoplication: A Systematic Review and Meta-Analysis. Principe J(1), Angeramo CA(1), Barros Sosa J(1), Baz Gallego JJ(1), Herbella FAM(2), Patti MG

6.
🔬 메타분석
Global prevalence and risk of gastroesophageal reflux disease symptoms in pregnancy: a systematic review and meta-analysis.
BMC pregnancy and childbirth 2025 PMID:41366751
📊 OR 8.37 (95% CI 27.63–54.28)

6. BMC Pregnancy Childbirth. 2025 Dec 9;26(1):44. doi: 10.1186/s12884-025-08569-x. Global prevalence and risk of gastroesophageal reflux disease symptoms in pregnancy: a systematic review and meta-analysis. Khurmatullina AR(1), Andreev DN(2), Maev IV(3), Lyamina SV(3), Kucheryavyy YA(4), Beliy P

7.
🔬 메타분석
Durability and reflux outcomes of peroral endoscopic myotomy compared to laparoscopic heller myotomy in achalasia: a meta-analysis of long-term studies.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 2025 PMID:41348606
📊 OR 1.43 · n=1158

7. Dis Esophagus. 2025 Nov 1;38(6):doaf111. doi: 10.1093/dote/doaf111. Durability and reflux outcomes of peroral endoscopic myotomy compared to laparoscopic heller myotomy in achalasia: a meta-analysis of long-term studies. Abosheisha M(1), Nasr E(2), Kandeel M(3), Asaad A(4), Alhammali T(5), Ale

8.
🔬 메타분석
[Safety and efficacy of endoscopic and surgical anti-reflux procedures for gastroesophageal reflux disease: a systematic review and network meta-analysis].
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 2025 PMID:41139639

8. Zhonghua Wei Chang Wai Ke Za Zhi. 2025 Oct 25;28(10):1161-1178. doi: 10.3760/cma.j.cn441530-20250724-00280. [Safety and efficacy of endoscopic and surgical anti-reflux procedures for gastroesophageal reflux disease: a systematic review and network meta-analysis]. [Article in Chinese; Abstract

9.
🔬 메타분석
The positive role of Chinese herbal medicine as an adjunctive therapy for refractory gastroesophageal reflux disease: A systematic review and network meta-analysis.
Medicine 2025 PMID:40419902

9. Medicine (Baltimore). 2025 May 23;104(21):e42565. doi: 10.1097/MD.0000000000042565. The positive role of Chinese herbal medicine as an adjunctive therapy for refractory gastroesophageal reflux disease: A systematic review and network meta-analysis. Zhang R(1), Yang Z(1), Pan X(1)(2), Liu Y(1

10.
🔬 메타분석
A systematic review and meta-analysis of randomized controlled trials: the role of potassium-competitive acid blockers in endoscopy-negative reflux disease.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2025 PMID:40382208

10. Dig Liver Dis. 2025 Sep;57(9):1752-1760. doi: 10.1016/j.dld.2025.04.045. Epub 2025 May 16. A systematic review and meta-analysis of randomized controlled trials: the role of potassium-competitive acid blockers in endoscopy-negative reflux disease. Koo TH(1), Fass R(2). Author information: (

11.
🧪 RCT
Wedge Pillow Versus Evening Proton Pump Inhibitor for Nocturnal Reflux Symptoms: A Noninferiority Randomized Trial.
Neurogastroenterology and motility 2026 PMID:41630402

11. Neurogastroenterol Motil. 2026 Feb;38(2):e70256. doi: 10.1111/nmo.70256. Wedge Pillow Versus Evening Proton Pump Inhibitor for Nocturnal Reflux Symptoms: A Noninferiority Randomized Trial. Hirunrattanaporn K(1), Prueksapanich P(1), Gonlachanvit S(1)(2), Patcharatrakul T(1)(2). Author inform

12.
🧪 RCT
Acupuncture provides a safe strategy to minimize proton pump inhibitor dose in resistant gastroesophageal reflux disease: randomized controlled trial.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 2026 PMID:41609334

12. Dis Esophagus. 2026 Jan 9;39(1):doag001. doi: 10.1093/dote/doag001. Acupuncture provides a safe strategy to minimize proton pump inhibitor dose in resistant gastroesophageal reflux disease: randomized controlled trial. Ghadiani Z(1), Gorjizadeh N(1), Azadvari M(2), Sharifi A(1), Jamali R(1).

13.
🧪 RCT
Role of antireflux mucosal ablation in "reflux-predominant" refractory gastroesophageal reflux disease: a randomized sham-controlled trial.
Endoscopy 2026 PMID:41197984

13. Endoscopy. 2026 May;58(5):456-464. doi: 10.1055/a-2740-9297. Epub 2025 Nov 6. Role of antireflux mucosal ablation in "reflux-predominant" refractory gastroesophageal reflux disease: a randomized sham-controlled trial. Chavan D(1), Koduri KK(1), Singh AP(1), Maragoni RG(1), Jagtap N(1), Kalapa

14.
🧪 RCT
A randomized, three-way crossover clinical trial on the efficacy of Mastiha based therapies (Pistacia lentiscus var. Chia) in functional dyspepsia.
Pharmacological research 2025 PMID:41197785

14. Pharmacol Res. 2025 Dec;222:108019. doi: 10.1016/j.phrs.2025.108019. Epub 2025 Nov 4. A randomized, three-way crossover clinical trial on the efficacy of Mastiha based therapies (Pistacia lentiscus var. Chia) in functional dyspepsia. Kleftaki SA(1), Amerikanou C(2), Tzavara C(1), Biagki T(1)

15.
📄 연구
Uncovering the Mechanisms of Failure of Proton Pump Inhibitors in GERD: The Role of Esophageal Acid Sensitivity.
Digestive diseases and sciences 2026 PMID:41026367

15. Dig Dis Sci. 2026 Mar;71(3):1041-1048. doi: 10.1007/s10620-025-09450-9. Epub 2025 Sep 30. Uncovering the Mechanisms of Failure of Proton Pump Inhibitors in GERD: The Role of Esophageal Acid Sensitivity. Gardner JD(1)(2), Triadafilopoulos G(3)(4). Author information: (1)Science for Organizat

16.
📄 연구
Comparable efficacy of generic and original alginate for symptom control in PPI-refractory GERD.
Scientific reports 2025 PMID:40760009

36. Sci Rep. 2025 Aug 4;15(1):28429. doi: 10.1038/s41598-025-13400-w. Comparable efficacy of generic and original alginate for symptom control in PPI-refractory GERD. Tangvoraphonkchai K(1), Manasirisuk W(2), Apichatvullop T(3), Srikhajonjit S(3), Mitpracha M(3), Promsen P(4), Preechakawin N(5),

17.
📄 연구
Exploratory analyses of meal-induced heartburn identify distinct clinical phenotypes of gastroesophageal reflux disease.
Physiological reports 2025 PMID:40693327

31. Physiol Rep. 2025 Jul;13(14):e70469. doi: 10.14814/phy2.70469. Exploratory analyses of meal-induced heartburn identify distinct clinical phenotypes of gastroesophageal reflux disease. Gardner JD(1)(2), Triadafilopoulos G(2)(3). Author information: (1)Science for Organizations, Mill Valley, C

18.
🧪 RCT
Zatariamultiflora hydroalcoholic extract: A triple-blind randomized controlled trial on immune genes, inflammation, and ulcerative colitis symptoms.
Journal of ethnopharmacology 2025 PMID:39987994

46. J Ethnopharmacol. 2025 Mar 26;344:119527. doi: 10.1016/j.jep.2025.119527. Epub 2025 Feb 21. Zatariamultiflora hydroalcoholic extract: A triple-blind randomized controlled trial on immune genes, inflammation, and ulcerative colitis symptoms. Morvaridi M(1), Aryaeian N(2), Alavinejad P(3), Sey

19.
🧪 RCT
Efficacy and Safety of GutGard® in Managing Gastroesophageal Reflux-Related Symptoms: A Phase III, Single-Centre, Double-Blind, Randomized Placebo-Controlled Trial.
Complementary medicine research 2025 PMID:39929150

40. Complement Med Res. 2025;32(1):26-36. doi: 10.1159/000543367. Epub 2025 Feb 10. Efficacy and Safety of GutGard® in Managing Gastroesophageal Reflux-Related Symptoms: A Phase III, Single-Centre, Double-Blind, Randomized Placebo-Controlled Trial. Raj JP(1)(2), Saxena U(2), Belhekar MN(2), Mamd

20.
🧪 RCT
Iodine Staining With Distance Countdown Improving the Safety for Reduction of Adverse Events: A Randomized Controlled Trial.
Clinical and translational gastroenterology 2025 PMID:39836052

7. Clin Transl Gastroenterol. 2025 Mar 1;16(3):e00822. doi: 10.14309/ctg.0000000000000822. Iodine Staining With Distance Countdown Improving the Safety for Reduction of Adverse Events: A Randomized Controlled Trial. Xi M(1)(2), Luo X(3), Chen F(1)(2), Wang Z(1)(2), Xiao X(1)(2), Luo B(1)(2), Ch

21.
📄 연구
Helichrysum odoratissimum (L.) Less: A Review of Its Volatile and Non-Volatile Compounds, Ethnomedicine, Pharmacological Properties and Evidence on Safety Trials in Humans.
Plants (Basel, Switzerland) 2026 PMID:42075477

36. Plants (Basel). 2026 Apr 21;15(8):1275. doi: 10.3390/plants15081275. Helichrysum odoratissimum (L.) Less: A Review of Its Volatile and Non-Volatile Compounds, Ethnomedicine, Pharmacological Properties and Evidence on Safety Trials in Humans. Ramadwa TE(1), Meddows-Taylor S(1). Author inform

22.
📄 연구
Dual Primary Gastric and Rectal Adenocarcinoma: A Case Report with Management Insights : Dual Primary Gastric and Rectal Adenocarcinoma.
Galen medical journal 2025 PMID:42038903

23. Galen Med J. 2025 Jul 7;14:e3742. doi: 10.31661/gmj.v14i.3742. eCollection 2025. Dual Primary Gastric and Rectal Adenocarcinoma: A Case Report with Management Insights : Dual Primary Gastric and Rectal Adenocarcinoma. Dastjerdi A(1), Samami E(2), Javadinia SA(3), Anvary M(4), Kazemzadeh A(5),

23.
📄 연구
Functional Esophageal Disorders.
Gastroenterology 2026 PMID:42031441

4. Gastroenterology. 2026 May;170(6):1224-1239. doi: 10.1053/j.gastro.2026.02.005. Epub 2026 Feb 18. Functional Esophageal Disorders. Gyawali CP(1), Roman S(2), Zerbib F(3), Savarino EV(4), Bhatia S(5), Fass R(6), Pandolfino JE(7). Author information: (1)Division of Gastroenterology, Washington

24.
🔬 메타분석
Tegoprazan in Gastroesophageal Reflux Disease and Related Acid-Mediated Conditions: A Systematic Review and Meta-Analysis.
JGH open : an open access journal of gastroenterology and hepatology 2026 PMID:42006860
📊 RR 1.01 (95% CI 0.98–1.05) · n=2492

45. JGH Open. 2026 Apr 17;10(4):e70406. doi: 10.1002/jgh3.70406. eCollection 2026 Apr. Tegoprazan in Gastroesophageal Reflux Disease and Related Acid-Mediated Conditions: A Systematic Review and Meta-Analysis. Bandyopadhyay S(1), Goenka M(2), Routh D(3), Ramesh GN(4), Lawate P(5). Author inform

25.
📄 연구
Effect of endoscopic pre-aponeurotic repair of diastasis recti on gastroesophageal reflux symptoms: An observational retrospective study.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 2026 PMID:41989733

31. Indian J Gastroenterol. 2026 Apr 16. doi: 10.1007/s12664-026-01995-5. Online ahead of print. Effect of endoscopic pre-aponeurotic repair of diastasis recti on gastroesophageal reflux symptoms: An observational retrospective study. Cuccomarino S(1), Toscano A(2), Palmisano EM(3), Juárez Muas

26.
📄 연구
Real-World Effectiveness and Safety of Saccharomyces boulardii CNCM I-745 as Adjunct Therapy for Helicobacter pylori Eradication: Data From the European Registry on H. pylori Management (Hp-EuReg).
Helicobacter 2026 PMID:41923280
📊 OR 2.32

16. Helicobacter. 2026 Mar-Apr;31(2):e70119. doi: 10.1111/hel.70119. Real-World Effectiveness and Safety of Saccharomyces boulardii CNCM I-745 as Adjunct Therapy for Helicobacter pylori Eradication: Data From the European Registry on H. pylori Management (Hp-EuReg). Nyssen OP(1), Jonaitis L(2),

27.
📄 연구
Systemic bismuth absorption and safety of the gastric mucosal protective bismuth potassium citrate, administered as granules and tablets in healthy Chinese and validation of a new, ICP-MS bismuth assay.
International journal of clinical pharmacology and therapeutics 2026 PMID:41878940

42. Int J Clin Pharmacol Ther. 2026 Mar 25. doi: 10.5414/CP204626. Online ahead of print. Systemic bismuth absorption and safety of the gastric mucosal protective bismuth potassium citrate, administered as granules and tablets in healthy Chinese and validation of a new, ICP-MS bismuth assay. Lv

28.
📄 연구
Self-management of reflux-like symptoms: A patient-centered decision-making approach.
Digestive diseases (Basel, Switzerland) 2026 PMID:41875283

49. Dig Dis. 2026 Mar 24:1-22. doi: 10.1159/000551414. Online ahead of print. Self-management of reflux-like symptoms: A patient-centered decision-making approach. Hungin APS, Scarpignato C, Bredenoord AJ, Fox MR, López-Pintor E, Mendive JM, Savarino EV, Kahrilas PJ. BACKGROUND: Guidelines for

29.
📄 연구
Managing reflux after tubular gastric esophageal substitution.
World journal of gastrointestinal surgery 2026 PMID:41809354

29. World J Gastrointest Surg. 2026 Feb 27;18(2):116235. doi: 10.4240/wjgs.v18.i2.116235. Managing reflux after tubular gastric esophageal substitution. Yan LJ(1), Shen SW(1), Fang TT(2). Author information: (1)Department of Thoracic Surgery, Affiliated Hospital of Jiangnan University, Wuxi 214

30.
📄 연구
Dietary Prebiotics Modulate Omeprazole-Induced Alterations in the Gut Microbial Signature.
Molecular nutrition & food research 2025 PMID:41169038

20. Mol Nutr Food Res. 2025 Dec;69(24):e70307. doi: 10.1002/mnfr.70307. Epub 2025 Oct 30. Dietary Prebiotics Modulate Omeprazole-Induced Alterations in the Gut Microbial Signature. Buccola MJ(1), Satheesh Babu AK(1), Paz HA(2)(3), Porter ND(1), Srinivasan H(1), Ricks RL(1), Rosquist K(1), Torre

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