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D-만노스

D-Mannose

📑 PubMed 27편 🌿 허브 🗓️ 최신 2026
🔬 메타분석 4 📋 체계적 리뷰 1 🧪 RCT 8

📖 핵심 요약

📖 27편 · 14분 읽기

D-만노스은(는) 허브 계열 보충제입니다. PubMed에 27편의 관련 논문이 있습니다.

📊 효과 크기 분포 (Forest plot)

각 연구의 효과 추정치와 95% 신뢰구간. 개별 연구를 통합(pooling)하지 않고 그대로 표시합니다.

390956660.65410047040.57 (0.29–1.15)285549261.52 (0.61–0.95)0.215RR (favours ← / →)

📚 관련 논문 (27편) · 📊 정량 근거 3건

1.
🔬 메타분석
Nonantibiotic prophylaxis for urinary tract infections: a network meta-analysis of randomized controlled trials.
Infection 2025 PMID:39095666
📊 RR 0.65 · n=495

1. Infection. 2025 Apr;53(2):535-546. doi: 10.1007/s15010-024-02357-z. Epub 2024 Aug 2. Nonantibiotic prophylaxis for urinary tract infections: a network meta-analysis of randomized controlled trials. Han Z(1), Yi X(1), Li J(1), Liao D(1), Ai J(2). Author information: (1)Department of Urology,

2.
📄 연구
Rapid and Esthetic Wound Healing in Surgery by Applying a Powdered Mixture of Mannose and Calcium Propionate.
Aesthetic plastic surgery 2025 PMID:40906289

2. Aesthetic Plast Surg. 2025 Nov;49(21):6162-6167. doi: 10.1007/s00266-025-05186-z. Epub 2025 Sep 4. Rapid and Esthetic Wound Healing in Surgery by Applying a Powdered Mixture of Mannose and Calcium Propionate. Ciucanu CI(1), Raţiu S(2), Olariu S(3), Ciucanu I(4). Author information: (1)Facult

3.
🧪 RCT
Comparison of increased hydration, D-mannose, and antibiotic prophylaxis for recurrent urinary tract infection prevention in premenopausal women: a three-arm randomized-controlled study.
International urology and nephrology 2026 PMID:40853430

3. Int Urol Nephrol. 2026 Mar;58(3):881-887. doi: 10.1007/s11255-025-04747-0. Epub 2025 Aug 25. Comparison of increased hydration, D-mannose, and antibiotic prophylaxis for recurrent urinary tract infection prevention in premenopausal women: a three-arm randomized-controlled study. Iossa V(1),

4.
🧪 RCT
Adding collagen, propolis plus quercetin, bacillus coagulans, hyaluronic acid and chondroitin sulphate to D-mannose avoids symptoms and prevents recurrence in women with recurrent urinary tract infections: a single-blind randomized controlled trial.
Expert review of anti-infective therapy 2025 PMID:40162673

4. Expert Rev Anti Infect Ther. 2025 Jul;23(7):523-530. doi: 10.1080/14787210.2025.2487162. Epub 2025 Apr 3. Adding collagen, propolis plus quercetin, bacillus coagulans, hyaluronic acid and chondroitin sulphate to D-mannose avoids symptoms and prevents recurrence in women with recurrent urinary

5.
📄 연구
[Experience with UroBest in patients with acute cystitis].
Urologiia (Moscow, Russia : 1999) 2024 PMID:39563582

5. Urologiia. 2024 Sep;(4):41-47. [Experience with UroBest in patients with acute cystitis]. [Article in Russian] Kyzlasov P S(1)(2), Neymark B A(1)(2), Kuzmenko A V(1)(2), Abuev G G(1)(2), Gyaurgiev T A(1)(2), Kuzmenko G A(1)(2). Author information: (1)A.I. Burnazyan SRC FMBC, FMBA of Russia,

6.
🧪 RCT
Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial.
The journal of sexual medicine 2024 PMID:38721680

6. J Sex Med. 2024 Jun 27;21(7):627-634. doi: 10.1093/jsxmed/qdae052. Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial. Boeri L(1

7.
🧪 RCT
Randomized clinical trial of non-antibiotic prophylaxis with d-Mannose plus Proanthocyanidins vs. Proanthocyanidins alone for urinary tract infections and asymptomatic bacteriuria in de novo kidney transplant recipients: The Manotras study.
Nefrologia 2024 PMID:38637262

7. Nefrologia (Engl Ed). 2024 May-Jun;44(3):408-416. doi: 10.1016/j.nefroe.2024.02.011. Epub 2024 Apr 17. Randomized clinical trial of non-antibiotic prophylaxis with d-Mannose plus Proanthocyanidins vs. Proanthocyanidins alone for urinary tract infections and asymptomatic bacteriuria in de novo

8.
🧪 RCT
d-Mannose for Prevention of Recurrent Urinary Tract Infection Among Women: A Randomized Clinical Trial.
JAMA internal medicine 2024 PMID:38587819

8. JAMA Intern Med. 2024 Jun 1;184(6):619-628. doi: 10.1001/jamainternmed.2024.0264. d-Mannose for Prevention of Recurrent Urinary Tract Infection Among Women: A Randomized Clinical Trial. Hayward G(1), Mort S(1), Hay AD(2), Moore M(3), Thomas NPB(4)(5), Cook J(1), Robinson J(1), Williams N(1),

9.
🧪 RCT
D-Mannose Plus Saccharomyces boulardii to Prevent Urinary Tract Infections and Discomfort after Cystoscopy: A Single-Center Prospective Randomized Pilot Study.
Medicina (Kaunas, Lithuania) 2023 PMID:37374369

9. Medicina (Kaunas). 2023 Jun 17;59(6):1165. doi: 10.3390/medicina59061165. D-Mannose Plus Saccharomyces boulardii to Prevent Urinary Tract Infections and Discomfort after Cystoscopy: A Single-Center Prospective Randomized Pilot Study. Quattrone C(1), Manfredi C(1), Napolitano L(2), Ferraro A(3)

10.
🧪 RCT
d-Mannose for Recurrent Urinary Tract Infection Prevention in Postmenopausal Women Using Vaginal Estrogen: A Randomized Controlled Trial.
Urogynecology (Philadelphia, Pa.) 2023 PMID:36808931

10. Urogynecology (Phila). 2023 Mar 1;29(3):367-377. doi: 10.1097/SPV.0000000000001270. Epub 2022 Oct 15. d-Mannose for Recurrent Urinary Tract Infection Prevention in Postmenopausal Women Using Vaginal Estrogen: A Randomized Controlled Trial. Lenger SM, Chu CM, Ghetti C(1), Durkin MJ(2), Jennin

11.
🧪 RCT
A Randomized Controlled Trial Comparing a New D-Mannose-based Dietary Supplement to Placebo for the Treatment of Uncomplicated Escherichia coli Urinary Tract Infections.
European urology focus 2023 PMID:36621376

11. Eur Urol Focus. 2023 Jul;9(4):654-659. doi: 10.1016/j.euf.2022.12.013. Epub 2023 Jan 6. A Randomized Controlled Trial Comparing a New D-Mannose-based Dietary Supplement to Placebo for the Treatment of Uncomplicated Escherichia coli Urinary Tract Infections. Salvatore S(1), Ruffolo AF(2), St

12.
📄 연구
The synergy of tea tree oil nano-emulsion and antibiotics against multidrug-resistant bacteria.
Journal of applied microbiology 2023 PMID:37401131

12. J Appl Microbiol. 2023 Jul 4;134(7):lxad131. doi: 10.1093/jambio/lxad131. The synergy of tea tree oil nano-emulsion and antibiotics against multidrug-resistant bacteria. Wei S(1)(2)(3), Tian Q(1)(2)(3), Husien HM(1)(2)(3)(4), Tao Y(1)(2)(3), Liu X(1)(2)(3), Liu M(1)(2)(3), Bo R(1)(2)(3), Li

13.
📄 연구
Experimental evidence for the existence of the passive antitumor defense system formed by the synergistic action of certain small substances of the circulatory system.
Cancer biotherapy & radiopharmaceuticals 2003 PMID:14969607

13. Cancer Biother Radiopharm. 2003 Dec;18(6):949-63. doi: 10.1089/108497803322702914. Experimental evidence for the existence of the passive antitumor defense system formed by the synergistic action of certain small substances of the circulatory system. Kulcsár G(1). Author information: (1)De

14.
📄 연구
Effect of Amorphophallus Konjac oligosaccharides on STZ-induced diabetes model of isolated islets.
Life sciences 2002 PMID:12467911

14. Life Sci. 2002 Dec 27;72(6):711-9. doi: 10.1016/s0024-3205(02)02303-2. Effect of Amorphophallus Konjac oligosaccharides on STZ-induced diabetes model of isolated islets. Lu XJ(1), Chen XM, Fu DX, Cong W, Ouyang F. Author information: (1)National Laboratory of Biochemical Engineering, Institu

15.
📄 연구
Antihuman epidermal growth factor receptor 2 antibody herceptin inhibits autocrine motility factor (AMF) expression and potentiates antitumor effects of AMF inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002 PMID:12374700

15. Clin Cancer Res. 2002 Oct;8(10):3285-9. Antihuman epidermal growth factor receptor 2 antibody herceptin inhibits autocrine motility factor (AMF) expression and potentiates antitumor effects of AMF inhibitors. Talukder AH(1), Bagheri-Yarmand R, Williams RR, Ragoussis J, Kumar R, Raz A. Autho

16.
📄 연구
Enhancing effect of saccharides on the mutagenicity of 2-chloro-4-methylthiobutanoic acid.
Mutation research 2000 PMID:10894898

11. Mutat Res. 2000 Jul 20;452(1):139-44. doi: 10.1016/s0027-5107(00)00061-0. Enhancing effect of saccharides on the mutagenicity of 2-chloro-4-methylthiobutanoic acid. Kimura S(1), Arimoto-Kobayashi S, Hayatsu H. Author information: (1)School of Humanities for Environmental Policy and Technolog

17.
📄 연구
Chronic insulin effects on insulin signalling and GLUT4 endocytosis are reversed by metformin.
The Biochemical journal 2000 PMID:10794717

13. Biochem J. 2000 May 15;348 Pt 1(Pt 1):83-91. Chronic insulin effects on insulin signalling and GLUT4 endocytosis are reversed by metformin. Pryor PR(1), Liu SC, Clark AE, Yang J, Holman GD, Tosh D. Author information: (1)Department of Biology and Biochemistry, University of Bath, UK. Decrea

18.
📄 연구
Interference of D-mannose in glucose measurements by glucose oxidase and hexokinase methods.
Clinical chemistry 1991 PMID:2004464

38. Clin Chem. 1991 Mar;37(3):477. Interference of D-mannose in glucose measurements by glucose oxidase and hexokinase methods. Ho CS, Fung SL, Chan AY. Comment on Clin Chem. 1987 May;33(5):708-10. PMID: 2004464 [Indexed for MEDLINE]

19.
📄 연구
[Immunochemical analysis of lectin receptors in the structure of trophoblastic beta 1-glycoprotein and pregnancy-associated alpha 2-glycoprotein].
Ontogenez 1987 PMID:2443885

2. Ontogenez. 1987 Jul-Aug;18(4):394-8. [Immunochemical analysis of lectin receptors in the structure of trophoblastic beta 1-glycoprotein and pregnancy-associated alpha 2-glycoprotein]. [Article in Russian] Krivonosov SK, Zorin NA, Ionova NK, Pogorelova TIu, Tatarinov IuS. Trophoblastic beta-g

20.
📄 연구
Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance.
The Journal of biological chemistry 1987 PMID:3539929

11. J Biol Chem. 1987 Jan 5;262(1):189-97. Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance. Garvey WT, Olefsky JM, Matthaei S, Marshall S. We have previously shown in primary cultured rat adipocytes that insulin a

21.
📄 연구
Natural killer (NK) cell-derived hematopoietic colony-inhibiting activity and NK cytotoxic factor. Relationship with tumor necrosis factor and synergism with immune interferon.
The Journal of experimental medicine 1985 PMID:3932579

34. J Exp Med. 1985 Nov 1;162(5):1512-30. doi: 10.1084/jem.162.5.1512. Natural killer (NK) cell-derived hematopoietic colony-inhibiting activity and NK cytotoxic factor. Relationship with tumor necrosis factor and synergism with immune interferon. Degliantoni G, Murphy M, Kobayashi M, Francis MK

22.
🔬 메타분석
Efficacy of D-mannose as prophylaxis of recurrent urinary tract infection: a systematic review and meta-analysis of randomized controlled trials.
Jornal brasileiro de nefrologia 2025 PMID:41004704
📊 RR 0.57 (95% CI 0.29–1.15) · n=167

13. J Bras Nefrol. 2025 Oct-Dec;47(4):e20250169. doi: 10.1590/2175-8239-JBN-2025-0169en. Efficacy of D-mannose as prophylaxis of recurrent urinary tract infection: a systematic review and meta-analysis of randomized controlled trials. Vargas CEF(1), Mutarelli A(1)(2), Menegardo LG(3), Silva AKBD

23.
📄 연구
D-mannose for preventing and treating urinary tract infections.
The Cochrane database of systematic reviews 2022 PMID:36041061

16. Cochrane Database Syst Rev. 2022 Aug 30;8(8):CD013608. doi: 10.1002/14651858.CD013608.pub2. D-mannose for preventing and treating urinary tract infections. Cooper TE(1)(2), Teng C(2)(3), Howell M(2)(3), Teixeira-Pinto A(2)(3), Jaure A(2)(3), Wong G(2)(3)(4). Author information: (1)Cochrane

24.
📋 체계적 리뷰
Role of D-Mannose in the Prevention of Recurrent Urinary Tract Infections: Evidence from a Systematic Review of the Literature.
European urology focus 2021 PMID:32972899

9. Eur Urol Focus. 2021 Sep;7(5):1166-1169. doi: 10.1016/j.euf.2020.09.004. Epub 2020 Sep 22. Role of D-Mannose in the Prevention of Recurrent Urinary Tract Infections: Evidence from a Systematic Review of the Literature. Kyriakides R(1), Jones P(1), Somani BK(2). Author information: (1)Departm

25.
🔬 메타분석
D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis.
American journal of obstetrics and gynecology 2020 PMID:32497610

40. Am J Obstet Gynecol. 2020 Aug;223(2):265.e1-265.e13. doi: 10.1016/j.ajog.2020.05.048. Epub 2020 Jun 1. D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis. Lenger SM(1), Bradley MS(2), Thomas DA(3), Bertolet MH(4),

26.
📄 연구
Prevention and treatment of uncomplicated lower urinary tract infections in the era of increasing antimicrobial resistance-non-antibiotic approaches: a systemic review.
Archives of gynecology and obstetrics 2019 PMID:31350663

50. Arch Gynecol Obstet. 2019 Oct;300(4):821-828. doi: 10.1007/s00404-019-05256-z. Epub 2019 Jul 26. Prevention and treatment of uncomplicated lower urinary tract infections in the era of increasing antimicrobial resistance-non-antibiotic approaches: a systemic review. Wawrysiuk S(1), Naber K(2

27.
🔬 메타분석
Long-term antibiotics for prevention of recurrent urinary tract infection in older adults: systematic review and meta-analysis of randomised trials.
BMJ open 2017 PMID:28554926
📊 RR 1.52 (95% CI 0.61–0.95) · n=150

47. BMJ Open. 2017 May 29;7(5):e015233. doi: 10.1136/bmjopen-2016-015233. Long-term antibiotics for prevention of recurrent urinary tract infection in older adults: systematic review and meta-analysis of randomised trials. Ahmed H(1), Davies F(1), Francis N(1), Farewell D(1), Butler C(2), Paranjo

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