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칼슘 (구연산칼슘)

Calcium (Citrate)

📑 PubMed 27편 ⚗️ 미네랄 🗓️ 최신 2026
🔬 메타분석 4 📋 체계적 리뷰 3 🧪 RCT 6

📖 핵심 요약

📖 27편 · 14분 읽기

칼슘 (구연산칼슘)은(는) 미네랄 계열 보충제입니다. PubMed에 27편의 관련 논문이 있습니다.

💊⚠️ 약물 상호작용 (1)

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Levothyroxine ⚠️ 보통

영향: 갑상선약 흡수율 감소 → TSH 상승

대처: 4시간 이상 간격으로 복용

📚 관련 논문 (27편) · 📊 정량 근거 2건

1.
🔬 메타분석
Meta-analysis of calcium bioavailability: a comparison of calcium citrate with calcium carbonate.
American journal of therapeutics 1999 PMID:11329115

1. Am J Ther. 1999 Nov;6(6):313-21. doi: 10.1097/00045391-199911000-00005. Meta-analysis of calcium bioavailability: a comparison of calcium citrate with calcium carbonate. Sakhaee K(1), Bhuket T, Adams-Huet B, Rao DS. Author information: (1)University of Texas Southwestern Medical School, Cente

2.
🧪 RCT
Comparison of calcium citrate and calcium carbonate absorption in patients with a Roux-en-Y gastric bypass, sleeve gastrectomy, and one-anastomosis gastric bypass: a double-blind, randomized cross-over trial.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2025 PMID:39603923

2. Surg Obes Relat Dis. 2025 Apr;21(4):471-481. doi: 10.1016/j.soard.2024.10.034. Epub 2024 Nov 6. Comparison of calcium citrate and calcium carbonate absorption in patients with a Roux-en-Y gastric bypass, sleeve gastrectomy, and one-anastomosis gastric bypass: a double-blind, randomized cross-

3.
📄 연구
The Effect of Multi-Ingredient Protein versus Collagen Supplementation on Satellite Cell Properties in Males and Females.
Medicine and science in sports and exercise 2024 PMID:39475860

3. Med Sci Sports Exerc. 2024 Nov 1;56(11):2125-2134. doi: 10.1249/MSS.0000000000003505. The Effect of Multi-Ingredient Protein versus Collagen Supplementation on Satellite Cell Properties in Males and Females. Wageh M(1), Fortino SA(1), Pontello R(1), Maklad A(1), McGlory C(1), Kumbhare D(2),

4.
🧪 RCT
The efficacy of oral vitamin D supplements on fusion outcome in patients receiving elective lumbar spinal fusion-a randomized control trial.
BMC musculoskeletal disorders 2022 PMID:36401234

4. BMC Musculoskelet Disord. 2022 Nov 18;23(1):996. doi: 10.1186/s12891-022-05948-9. The efficacy of oral vitamin D supplements on fusion outcome in patients receiving elective lumbar spinal fusion-a randomized control trial. Hu MH(#)(1)(2)(3), Tseng YK(#)(1), Chung YH(1)(4), Wu NY(5), Li CH(6),

5.
🧪 RCT
Urate-lowering effect of calcium supplementation: Analyses of a randomized controlled trial.
Clinical nutrition ESPEN 2022 PMID:35623880

5. Clin Nutr ESPEN. 2022 Jun;49:86-91. doi: 10.1016/j.clnesp.2022.02.121. Epub 2022 Mar 9. Urate-lowering effect of calcium supplementation: Analyses of a randomized controlled trial. Cândido FG(1), Alves RDM(2), Freitas DMO(2), Bittencourt JM(2), Rocha DMUP(2), Alfenas RCG(2). Author informat

6.
🧪 RCT
Calcium Citrate Versus Calcium Carbonate in the Management of Chronic Hypoparathyroidism: A Randomized, Double-Blind, Crossover Clinical Trial.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022 PMID:35466449

6. J Bone Miner Res. 2022 Jul;37(7):1251-1259. doi: 10.1002/jbmr.4564. Epub 2022 Jun 24. Calcium Citrate Versus Calcium Carbonate in the Management of Chronic Hypoparathyroidism: A Randomized, Double-Blind, Crossover Clinical Trial. Naciu AM(#)(1)(2), Tabacco G(#)(1)(2), Bilezikian JP(3), Santon

7.
🧪 RCT
Effect of high dose vitamin D supplementation on indices of sarcopenia and obesity assessed by DXA among older adults: A randomized controlled trial.
Endocrine 2022 PMID:35028890

7. Endocrine. 2022 Apr;76(1):162-171. doi: 10.1007/s12020-021-02951-3. Epub 2022 Jan 14. Effect of high dose vitamin D supplementation on indices of sarcopenia and obesity assessed by DXA among older adults: A randomized controlled trial. Jabbour J(1), Rahme M(2), Mahfoud ZR(3)(4), El-Hajj Fulei

8.
📄 연구
Vitamin D3 Dose Requirement That Raises 25-Hydroxyvitamin D to Desirable Level in Overweight and Obese Elderly.
The Journal of clinical endocrinology and metabolism 2021 PMID:33954783

8. J Clin Endocrinol Metab. 2021 Aug 18;106(9):e3644-e3654. doi: 10.1210/clinem/dgab296. Vitamin D3 Dose Requirement That Raises 25-Hydroxyvitamin D to Desirable Level in Overweight and Obese Elderly. Bacha DS(1), Rahme M(1), Al-Shaar L(2), Baddoura R(3), Halaby G(4), Singh RJ(5), Mahfoud ZR(6)

9.
📄 연구
The Effect of a Multi-ingredient Supplement on Resistance Training-induced Adaptations.
Medicine and science in sports and exercise 2021 PMID:33756525

9. Med Sci Sports Exerc. 2021 Aug 1;53(8):1699-1707. doi: 10.1249/MSS.0000000000002641. The Effect of a Multi-ingredient Supplement on Resistance Training-induced Adaptations. Wageh M(1), Fortino SA(1), McGlory C(1), Kumbhare D(2), Phillips SM(1), Parise G(1). Author information: (1)Department

10.
🧪 RCT
Effect of Bacillius Coagulans and Galactomannans on Obese Patients Undergoing Sleeve Gastrectomy, A Randomized-Controlled Clinical Trial.
Alternative therapies in health and medicine 2021 PMID:29874199

10. Altern Ther Health Med. 2021 Jun;27(S1):138-145. Effect of Bacillius Coagulans and Galactomannans on Obese Patients Undergoing Sleeve Gastrectomy, A Randomized-Controlled Clinical Trial. Kazzi F, Daher N, Zimmerman G, Garcia M, Schmidt N, Scharf K. BACKGROUND: The purpose of this study was t

11.
📄 연구
Persisting Hypocalcemia After Surgical Parathyroidectomy: The Differential Effectiveness of Calcium Citrate Versus Calcium Carbonate With Acid Suppression.
The American journal of the medical sciences 2017 PMID:28104108

11. Am J Med Sci. 2017 Jan;353(1):82-86. doi: 10.1016/j.amjms.2016.04.007. Epub 2016 Apr 22. Persisting Hypocalcemia After Surgical Parathyroidectomy: The Differential Effectiveness of Calcium Citrate Versus Calcium Carbonate With Acid Suppression. Afshan S(1), Farah Musa AR(2), Echols V(2), Ler

12.
📄 연구
The effect of vitamin D on calcium absorption in older women.
The Journal of clinical endocrinology and metabolism 2012 PMID:22855333

12. J Clin Endocrinol Metab. 2012 Oct;97(10):3550-6. doi: 10.1210/jc.2012-2020. Epub 2012 Aug 1. The effect of vitamin D on calcium absorption in older women. Gallagher JC(1), Yalamanchili V, Smith LM. Author information: (1)Bone Metabolism Unit, Creighton University Medical Center, 601 North 30

13.
📄 연구
Absorption of levothyroxine when coadministered with various calcium formulations.
Thyroid : official journal of the American Thyroid Association 2011 PMID:21595516

13. Thyroid. 2011 May;21(5):483-6. doi: 10.1089/thy.2010.0296. Absorption of levothyroxine when coadministered with various calcium formulations. Zamfirescu I(1), Carlson HE. Author information: (1)Endocrinology Division, Department of Medicine, Stony Brook University School of Medicine , Stony

14.
📄 연구
Hormone replacement after thyroid and parathyroid surgery.
Deutsches Arzteblatt international 2010 PMID:21173898

14. Dtsch Arztebl Int. 2010 Nov;107(47):827-34. doi: 10.3238/arztebl.2010.0827. Epub 2010 Nov 26. Hormone replacement after thyroid and parathyroid surgery. Schäffler A(1). Author information: (1)Klinik und Poliklinik für Innere Medizin I, Universität Regensburg, 93042 Regensburg, Germany. andr

15.
📄 연구
Aluminum citrate inhibits cytotoxicity and aggregation of oxalate crystals.
Toxicology 2007 PMID:17161516

15. Toxicology. 2007 Feb 12;230(2-3):117-25. doi: 10.1016/j.tox.2006.11.046. Epub 2006 Nov 15. Aluminum citrate inhibits cytotoxicity and aggregation of oxalate crystals. Guo C(1), McMartin KE. Author information: (1)Department of Pharmacology, Toxicology & Neuroscience, Louisiana State Univers

16.
📄 연구
Interaction of dietary calcium and protein in bone health in humans.
The Journal of nutrition 2003 PMID:12612168

36. J Nutr. 2003 Mar;133(3):852S-854S. doi: 10.1093/jn/133.3.852S. Interaction of dietary calcium and protein in bone health in humans. Dawson-Hughes B(1). Author information: (1)Calcium and Bone Metabolism Laboratory at the Jean Mayer U.S. Department of Agriculture Human Nutrition Research Cent

17.
📄 연구
Effect of estrogen treatment and vitamin D status on differing bioavailabilities of calcium carbonate and calcium citrate.
Journal of clinical pharmacology 2002 PMID:12412824

12. J Clin Pharmacol. 2002 Nov;42(11):1251-6. doi: 10.1177/009127002762491343. Effect of estrogen treatment and vitamin D status on differing bioavailabilities of calcium carbonate and calcium citrate. Heller HJ(1), Poindexter JR, Adams-Huet B. Author information: (1)Center for Mineral Metabolis

18.
📄 연구
Zinc balance in adolescent females consuming a low- or high-calcium diet.
The American journal of clinical nutrition 1997 PMID:9129477

38. Am J Clin Nutr. 1997 May;65(5):1460-4. doi: 10.1093/ajcn/65.5.1460. Zinc balance in adolescent females consuming a low- or high-calcium diet. McKenna AA(1), Ilich JZ, Andon MB, Wang C, Matkovic V. Author information: (1)Bone and Mineral Metabolism Laboratory, Ohio State University, Columbus;

19.
📄 연구
The effect of calcium carbonate and calcium citrate on the absorption of zinc in healthy female subjects.
European journal of clinical nutrition 1994 PMID:8194505

24. Eur J Clin Nutr. 1994 Mar;48(3):198-204. The effect of calcium carbonate and calcium citrate on the absorption of zinc in healthy female subjects. Argiratos V(1), Samman S. Author information: (1)Department of Biochemistry, University of Sydney, NSW, Australia. OBJECTIVES: The aim of this s

20.
📄 연구
Calcium citrate markedly enhances aluminum absorption from aluminum hydroxide.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1991 PMID:2042654

48. Am J Kidney Dis. 1991 Jun;17(6):708-11. doi: 10.1016/s0272-6386(12)80356-8. Calcium citrate markedly enhances aluminum absorption from aluminum hydroxide. Coburn JW(1), Mischel MG, Goodman WG, Salusky IB. Author information: (1)Medical Service, West Los Angeles Veterans Administration Center

21.
🔬 메타분석
Effect of Calcium Citrate Versus Calcium Carbonate on Parathyroid Hormone Levels in Patients Undergoing Bariatric Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Obesity surgery 2026 PMID:41806228
📊 MD 0.03 (95% CI -0.04–0.11) · n=227

35. Obes Surg. 2026 Apr;36(4):1495-1502. doi: 10.1007/s11695-026-08513-8. Epub 2026 Mar 10. Effect of Calcium Citrate Versus Calcium Carbonate on Parathyroid Hormone Levels in Patients Undergoing Bariatric Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Rahmani J

22.
📋 체계적 리뷰
Dietary interventions on nutritional management of population with urolithiasis: a systematic review of clinical evidence.
Nutrition research reviews 2025 PMID:40936162

3. Nutr Res Rev. 2025 Dec;38(2):973-988. doi: 10.1017/S0954422425100188. Epub 2025 Sep 12. Dietary interventions on nutritional management of population with urolithiasis: a systematic review of clinical evidence. Pacheco-Hernández B(1)(2), Sansores-España D(1)(3)(4), Medina-Vera I(5), Rubio-Za

23.
📋 체계적 리뷰
Changes in Urine Composition and Risk of Kidney Stone Disease Following Bariatric Surgery: A Systematic Review over Last 2 Decades.
Current urology reports 2022 PMID:36417046

49. Curr Urol Rep. 2022 Nov;23(11):279-295. doi: 10.1007/s11934-022-01119-4. Epub 2022 Nov 22. Changes in Urine Composition and Risk of Kidney Stone Disease Following Bariatric Surgery: A Systematic Review over Last 2 Decades. Gadiyar N(1), Geraghty RM(2), Premakumar Y(3), Somani BK(4). Author

24.
🔬 메타분석
Effect of dietary treatment and fluid intake on the prevention of recurrent calcium stones and changes in urine composition: A meta-analysis and systematic review.
PloS one 2021 PMID:33872340
📊 RR 2.32 (95% CI 0.42–12.85)

21. PLoS One. 2021 Apr 19;16(4):e0250257. doi: 10.1371/journal.pone.0250257. eCollection 2021. Effect of dietary treatment and fluid intake on the prevention of recurrent calcium stones and changes in urine composition: A meta-analysis and systematic review. Wang Z(1), Zhang Y(1), Wei W(1). Au

25.
📄 연구
Recommendations Based on Evidence by the Andalusian Group for Nutrition Reflection and Investigation (GARIN) for the Pre- and Postoperative Management of Patients Undergoing Obesity Surgery.
Nutrients 2020 PMID:32640531

43. Nutrients. 2020 Jul 6;12(7):2002. doi: 10.3390/nu12072002. Recommendations Based on Evidence by the Andalusian Group for Nutrition Reflection and Investigation (GARIN) for the Pre- and Postoperative Management of Patients Undergoing Obesity Surgery. Martínez-Ortega AJ(1)(2), Olveira G(3)(4)(

26.
📋 체계적 리뷰
Effects of different phosphate lowering strategies in patients with CKD on laboratory outcomes: A systematic review and NMA.
PloS one 2017 PMID:28248961

8. PLoS One. 2017 Mar 1;12(3):e0171028. doi: 10.1371/journal.pone.0171028. eCollection 2017. Effects of different phosphate lowering strategies in patients with CKD on laboratory outcomes: A systematic review and NMA. Sekercioglu N(1), Angeliki Veroniki A(2), Thabane L(1)(3)(4)(5)(6), Busse JW(

27.
🔬 메타분석
Comparative Effectiveness of Phosphate Binders in Patients with Chronic Kidney Disease: A Systematic Review and Network Meta-Analysis.
PloS one 2016 PMID:27276077

28. PLoS One. 2016 Jun 8;11(6):e0156891. doi: 10.1371/journal.pone.0156891. eCollection 2016. Comparative Effectiveness of Phosphate Binders in Patients with Chronic Kidney Disease: A Systematic Review and Network Meta-Analysis. Sekercioglu N(1), Thabane L(1)(2)(3)(4)(5), Díaz Martínez JP(1), Ne

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