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BCAA

BCAA (Branched-Chain Amino Acids)

📑 PubMed 30편 🧬 아미노산 🗓️ 최신 2025
🔬 메타분석 6 📋 체계적 리뷰 4 🧪 RCT 5

📖 핵심 요약

📖 30편 · 15분 읽기

BCAA은(는) 아미노산 계열 보충제입니다. 주로 항암, 뇌 건강, 당뇨 분야에서 연구되었으며, PubMed에 30편의 관련 논문이 있습니다.

🔍 연구 분야별 근거

항암 논문 1편
뇌 건강 논문 1편
당뇨 논문 3편

* 제목에 해당 키워드가 포함된 논문 수 (PubMed 근거)

📊 효과 크기 분포 (Forest plot)

각 연구의 효과 추정치와 95% 신뢰구간. 개별 연구를 통합(pooling)하지 않고 그대로 표시합니다.

362970952.08365649301.21 (1.09–1.3)384882652.750.215OR (favours ← / →)

📚 관련 논문 (30편) · 📊 정량 근거 5건

1.
🔬 메타분석
Dietary Branched Chain Amino Acids Association with Cancer and Mortality: A Systematic Review and Meta-Analysis of Observational Studies.
Nutrition and cancer 2024 PMID:38130073

1. Nutr Cancer. 2024;76(2):160-174. doi: 10.1080/01635581.2023.2292820. Epub 2024 Jan 18. Dietary Branched Chain Amino Acids Association with Cancer and Mortality: A Systematic Review and Meta-Analysis of Observational Studies. Tabesh M(1), Teymoori F(1)(2), Ahmadirad H(2), Mirmiran P(2), Rahide

2.
🔬 메타분석
Serum branched amino acids and the risk of all-cause mortality: a meta-analysis and systematic review.
Amino acids 2023 PMID:37725184
📊 RR 1.17 (95% CI 0.85–1.6)

2. Amino Acids. 2023 Nov;55(11):1475-1486. doi: 10.1007/s00726-023-03329-7. Epub 2023 Sep 19. Serum branched amino acids and the risk of all-cause mortality: a meta-analysis and systematic review. Teymoori F(#)(1)(2), Ahmadirad H(#)(1), Jahromi MK(3), Mokhtari E(1)(4), Farhadnejad H(1), Mohamma

3.
📋 체계적 리뷰
A Potential Role Exists for Nutritional Interventions in the Chronic Phase of Mild Traumatic Brain Injury, Concussion and Sports-Related Concussion: A Systematic Review.
Nutrients 2023 PMID:37686758

3. Nutrients. 2023 Aug 25;15(17):3726. doi: 10.3390/nu15173726. A Potential Role Exists for Nutritional Interventions in the Chronic Phase of Mild Traumatic Brain Injury, Concussion and Sports-Related Concussion: A Systematic Review. Ryan T(1), Nagle S(1), Daly E(1), Pearce AJ(2), Ryan L(1). Au

4.
🔬 메타분석
The Association between Circulating Branched Chain Amino Acids and the Temporal Risk of Developing Type 2 Diabetes Mellitus: A Systematic Review & Meta-Analysis.
Nutrients 2022 PMID:36297095
📊 OR 2.08

4. Nutrients. 2022 Oct 20;14(20):4411. doi: 10.3390/nu14204411. The Association between Circulating Branched Chain Amino Acids and the Temporal Risk of Developing Type 2 Diabetes Mellitus: A Systematic Review & Meta-Analysis. Ramzan I(1)(2), Ardavani A(1)(2), Vanweert F(3), Mellett A(1)(4), Athe

5.
📋 체계적 리뷰
Edible Insect Consumption for Human and Planetary Health: A Systematic Review.
International journal of environmental research and public health 2022 PMID:36141915

5. Int J Environ Res Public Health. 2022 Sep 15;19(18):11653. doi: 10.3390/ijerph191811653. Edible Insect Consumption for Human and Planetary Health: A Systematic Review. Ros-Baró M(1), Casas-Agustench P(1)(2), Díaz-Rizzolo DA(1)(3), Batlle-Bayer L(4), Adrià-Acosta F(5), Aguilar-Martínez A(6)(7)

6.
📋 체계적 리뷰
Gut Microbiota-Derived Metabolites and Cardiovascular Disease Risk: A Systematic Review of Prospective Cohort Studies.
Nutrients 2022 PMID:35807835

6. Nutrients. 2022 Jun 27;14(13):2654. doi: 10.3390/nu14132654. Gut Microbiota-Derived Metabolites and Cardiovascular Disease Risk: A Systematic Review of Prospective Cohort Studies. Sanchez-Gimenez R(1)(2)(3), Ahmed-Khodja W(2)(4), Molina Y(2), Peiró OM(1)(2)(3), Bonet G(1)(2)(3), Carrasquer A(

7.
📋 체계적 리뷰
Contribution of Biological Age-Predictive Biomarkers to Nutrition Research: A Systematic Review of the Current Evidence and Implications for Future Research and Clinical Practice.
Advances in nutrition (Bethesda, Md.) 2022 PMID:35612976

7. Adv Nutr. 2022 Oct 2;13(5):1930-1946. doi: 10.1093/advances/nmac060. Contribution of Biological Age-Predictive Biomarkers to Nutrition Research: A Systematic Review of the Current Evidence and Implications for Future Research and Clinical Practice. Siopis G(1)(2), Porter J(2). Author informa

8.
🔬 메타분석
The efficacy of parenteral nutrition (PN) and enteral nutrition (EN) supports in cirrhosis: A systematic review and network meta-analysis.
Medicine 2022 PMID:35060537

8. Medicine (Baltimore). 2022 Jan 21;101(3):e28618. doi: 10.1097/MD.0000000000028618. The efficacy of parenteral nutrition (PN) and enteral nutrition (EN) supports in cirrhosis: A systematic review and network meta-analysis. Yu B(1), Wang J(2). Author information: (1)Department of Pharmacy, Mia

9.
🔬 메타분석
Effects of branched-chain amino acid-rich supplementation on EWGSOP2 criteria for sarcopenia in older adults: a systematic review and meta-analysis.
European journal of nutrition 2022 PMID:34705076

9. Eur J Nutr. 2022 Mar;61(2):637-651. doi: 10.1007/s00394-021-02710-0. Epub 2021 Oct 27. Effects of branched-chain amino acid-rich supplementation on EWGSOP2 criteria for sarcopenia in older adults: a systematic review and meta-analysis. Bai GH(#)(1)(2), Tsai MC(#)(1)(2), Tsai HW(2)(3), Chang C

10.
🔬 메타분석
Are Supplemental Branched-Chain Amino Acids Beneficial During the Oncological Peri-Operative Period: A Systematic Review and Meta-Analysis.
Integrative cancer therapies 2021 PMID:33648360
📊 RR 0.62 (95% CI 0.44–0.87) · n=389

10. Integr Cancer Ther. 2021 Jan-Dec;20:1534735421997551. doi: 10.1177/1534735421997551. Are Supplemental Branched-Chain Amino Acids Beneficial During the Oncological Peri-Operative Period: A Systematic Review and Meta-Analysis. Cogo E(1), Elsayed M(1), Liang V(1), Cooley K(1)(2)(3)(4), Guerin C

11.
📄 연구
PNPLA3 Genotype and Dietary Fat Modify Concentrations of Plasma and Fecal Short Chain Fatty Acids and Plasma Branched-Chain Amino Acids.
Nutrients 2024 PMID:38257154

11. Nutrients. 2024 Jan 16;16(2):261. doi: 10.3390/nu16020261. PNPLA3 Genotype and Dietary Fat Modify Concentrations of Plasma and Fecal Short Chain Fatty Acids and Plasma Branched-Chain Amino Acids. Tauriainen MM(1)(2), Csader S(2), Lankinen M(2), Lo KK(3), Chen C(3), Lahtinen O(4), El-Nezamy H

12.
📄 연구
Vitamin D Supplementation Influences Ultramarathon-Induced Changes in Serum Amino Acid Levels, Tryptophan/Branched-Chain Amino Acid Ratio, and Arginine/Asymmetric Dimethylarginine Ratio.
Nutrients 2023 PMID:37630726

12. Nutrients. 2023 Aug 11;15(16):3536. doi: 10.3390/nu15163536. Vitamin D Supplementation Influences Ultramarathon-Induced Changes in Serum Amino Acid Levels, Tryptophan/Branched-Chain Amino Acid Ratio, and Arginine/Asymmetric Dimethylarginine Ratio. Mieszkowski J(1)(2), Brzezińska P(1), Stanki

13.
🧪 RCT
Effects of branched chain amino acids, l-citrulline, and alpha-glycerylphosphorylcholine supplementation on exercise performance in trained cyclists: a randomized crossover trial.
Journal of the International Society of Sports Nutrition 2023 PMID:37229544

13. J Int Soc Sports Nutr. 2023 Dec;20(1):2214112. doi: 10.1080/15502783.2023.2214112. Effects of branched chain amino acids, l-citrulline, and alpha-glycerylphosphorylcholine supplementation on exercise performance in trained cyclists: a randomized crossover trial. Harrington RN(1). Author in

14.
🧪 RCT
Branched-chain amino acids plus vitamin D supplementation promote increased muscle strength following lumbar surgery for lumbar spinal stenosis: a randomized trial.
The spine journal : official journal of the North American Spine Society 2023 PMID:36940921

14. Spine J. 2023 Jul;23(7):962-972. doi: 10.1016/j.spinee.2023.03.007. Epub 2023 Mar 20. Branched-chain amino acids plus vitamin D supplementation promote increased muscle strength following lumbar surgery for lumbar spinal stenosis: a randomized trial. Minetama M(1), Kawakami M(2), Teraguchi

15.
🧪 RCT
Branched Chain Amino Acids, New Target of Germinated Brown Rice against Type 2 Diabetes Mellitus: A Randomized Controlled Trial.
Molecular nutrition & food research 2023 PMID:36564930
📊 OR 1.21 (95% CI 1.09–1.3) · n=42

15. Mol Nutr Food Res. 2023 Feb;67(4):e2200481. doi: 10.1002/mnfr.202200481. Epub 2023 Jan 26. Branched Chain Amino Acids, New Target of Germinated Brown Rice against Type 2 Diabetes Mellitus: A Randomized Controlled Trial. Wan W(1)(2), Jiang X(3), Zhao R(4), Cai F(1)(2), Wu F(1)(2), Hu Y(1)(2),

16.
📄 연구
Postprandial Glucose and Gastrointestinal Hormone Responses of Healthy Subjects to Wheat Biscuits Enriched with L-Arginine or Branched-Chain Amino Acids of Plant Origin.
Nutrients 2022 PMID:36297065

50. Nutrients. 2022 Oct 19;14(20):4381. doi: 10.3390/nu14204381. Postprandial Glucose and Gastrointestinal Hormone Responses of Healthy Subjects to Wheat Biscuits Enriched with L-Arginine or Branched-Chain Amino Acids of Plant Origin. Yanni AE(1), Kokkinos A(2), Binou P(1), Papaioannou V(3), Hal

17.
📄 연구
Branched-Chain Amino Acids Supplementation Does Not Accelerate Recovery after a Change of Direction Sprinting Exercise Protocol.
Nutrients 2022 PMID:36297014

28. Nutrients. 2022 Oct 16;14(20):4331. doi: 10.3390/nu14204331. Branched-Chain Amino Acids Supplementation Does Not Accelerate Recovery after a Change of Direction Sprinting Exercise Protocol. Khemtong C(1)(2), Tessitore A(3), Jaime SJ(4), Gobbi G(5), Jensen J(6), Yang AL(1), Kuo CH(1), Condell

18.
🧪 RCT
The effects of the Green-Mediterranean diet on cardiometabolic health are linked to gut microbiome modifications: a randomized controlled trial.
Genome medicine 2022 PMID:35264213

10. Genome Med. 2022 Mar 10;14(1):29. doi: 10.1186/s13073-022-01015-z. The effects of the Green-Mediterranean diet on cardiometabolic health are linked to gut microbiome modifications: a randomized controlled trial. Rinott E(1), Meir AY(1), Tsaban G(1), Zelicha H(1), Kaplan A(1), Knights D(2)(3)

19.
📄 연구
Diabetes Remission Is Modulated by Branched Chain Amino Acids According to the Diet Consumed: From the CORDIOPREV Study.
Molecular nutrition & food research 2022 PMID:34863046

23. Mol Nutr Food Res. 2022 Feb;66(4):e2100652. doi: 10.1002/mnfr.202100652. Epub 2022 Jan 7. Diabetes Remission Is Modulated by Branched Chain Amino Acids According to the Diet Consumed: From the CORDIOPREV Study. Cardelo MP(1)(2)(3)(4), Alcala-Diaz JF(1)(2)(3)(4), Gutierrez-Mariscal FM(1)(2)(

20.
🧪 RCT
Sarcojoint®, the branched-chain amino acid-based supplement, plus resistance exercise improved muscle mass in adults aged 50 years and older: A double-blinded randomized controlled trial.
Experimental gerontology 2022 PMID:34838980

36. Exp Gerontol. 2022 Jan;157:111644. doi: 10.1016/j.exger.2021.111644. Epub 2021 Nov 26. Sarcojoint®, the branched-chain amino acid-based supplement, plus resistance exercise improved muscle mass in adults aged 50 years and older: A double-blinded randomized controlled trial. Peng LN(1), Yu P

21.
📄 연구
Minocycline Protects Against Oxidative Stress in a Model of Maple Syrup Urine Disease.
Neurochemical research 2025 PMID:40900409

4. Neurochem Res. 2025 Sep 3;50(5):280. doi: 10.1007/s11064-025-04549-x. Minocycline Protects Against Oxidative Stress in a Model of Maple Syrup Urine Disease. da Silva Lemos I(1), Seldenreich RF(1), Alano CG(1), Schmitt LQ(1), Matiola RT(1), De Pieri E(2), Petronilho F(3), Machado-De-Ávila RA(2

22.
📄 연구
Gut microbiome and host TOR pathway interact to regulate predator-induced aversive memory in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 2025 PMID:40540603

20. Proc Natl Acad Sci U S A. 2025 Jun 24;122(25):e2422928122. doi: 10.1073/pnas.2422928122. Epub 2025 Jun 20. Gut microbiome and host TOR pathway interact to regulate predator-induced aversive memory in Drosophila melanogaster. Chen HY(#)(1), Wu PS(#)(1), Li ZY(#)(1), Liu YC(1), Yeh SR(1)(2)(3)

23.
📄 연구
Single Amino Acid Supplementation in Inherited Metabolic Disorders: An Evidence-Based Review of Interventions.
Genes 2025 PMID:40428324

45. Genes (Basel). 2025 Apr 27;16(5):502. doi: 10.3390/genes16050502. Single Amino Acid Supplementation in Inherited Metabolic Disorders: An Evidence-Based Review of Interventions. Verduci E(1)(2), Tosi M(1)(3), Dionisi Vici C(4), Spada M(5). Author information: (1)Department of Health Sciences,

24.
📄 연구
Effect of different types of milk consumption on gout and the mediating effect of branched-chain amino acids: A Mendelian randomization study.
Journal of dairy science 2025 PMID:39892606

30. J Dairy Sci. 2025 Dec;108(12):12991-12996. doi: 10.3168/jds.2024-26088. Epub 2025 Jan 30. Effect of different types of milk consumption on gout and the mediating effect of branched-chain amino acids: A Mendelian randomization study. Han Q(1), Li XL(1), Xiao QA(2). Author information: (1)Dep

25.
📄 연구
Hemodiafiltration with endogenous reinfusion for uremic toxin removal in patients undergoing maintenance hemodialysis: a pilot study.
Renal failure 2024 PMID:38632963

27. Ren Fail. 2024 Dec;46(1):2338929. doi: 10.1080/0886022X.2024.2338929. Epub 2024 Apr 18. Hemodiafiltration with endogenous reinfusion for uremic toxin removal in patients undergoing maintenance hemodialysis: a pilot study. Lu R(1), Fang Y(1), Wu W(1), Zeng X(1), Liu T(1), Qian Y(1), Xie Y(1),

26.
📄 연구
Analyses of potential causal contributors to increased waist/hip ratio-associated cardiometabolic disease: A combined and sex-stratified Mendelian randomization study.
Diabetes, obesity & metabolism 2024 PMID:38488265
📊 OR 2.747

34. Diabetes Obes Metab. 2024 Jun;26(6):2284-2291. doi: 10.1111/dom.15542. Epub 2024 Mar 15. Analyses of potential causal contributors to increased waist/hip ratio-associated cardiometabolic disease: A combined and sex-stratified Mendelian randomization study. Hashemy H(1), Nguyen A(1), Khafagy

27.
📄 연구
Dietary branched-chain amino acids intake and new-onset hypertension: a nationwide prospective cohort study in China.
Amino acids 2024 PMID:38460031

10. Amino Acids. 2024 Mar 9;56(1):19. doi: 10.1007/s00726-023-03376-0. Dietary branched-chain amino acids intake and new-onset hypertension: a nationwide prospective cohort study in China. Yu L(1)(2), Zhu Q(3), Song P(2)(4), Li Y(2), Man Q(2), Liu B(2), Jia S(2), Zhang J(5). Author information:

28.
📄 연구
Effects of Livact Granule on Liver Function Recovery After Donor Right Hemi-Hepatectomy.
Transplantation proceedings 2024 PMID:38350820

19. Transplant Proc. 2024 Apr;56(3):656-659. doi: 10.1016/j.transproceed.2024.01.034. Epub 2024 Feb 13. Effects of Livact Granule on Liver Function Recovery After Donor Right Hemi-Hepatectomy. Na GH(1), Choi HJ(2), Chun JH(3), Choi Y(3), Park SE(3), Hong TH(3), You YK(3). Author information: (1

29.
📄 연구
Bergenin Alleviates Ulcerative Colitis By Decreasing Gut Commensal Bacteroides vulgatus-Mediated Elevated Branched-Chain Amino Acids.
Journal of agricultural and food chemistry 2024 PMID:38324392

36. J Agric Food Chem. 2024 Feb 21;72(7):3606-3621. doi: 10.1021/acs.jafc.3c09448. Epub 2024 Feb 7. Bergenin Alleviates Ulcerative Colitis By Decreasing Gut Commensal Bacteroides vulgatus-Mediated Elevated Branched-Chain Amino Acids. Huang TQ(1), Chen YX(1), Zeng SL(2), Lin Y(1), Li F(1), Jiang

30.
📄 연구
Exploring the Impact of Protein Supplement Source on Body Composition in Women Practicing Anaerobic Resistance Exercise: A Pilot Study.
Nutrients 2024 PMID:38276559

16. Nutrients. 2024 Jan 22;16(2):321. doi: 10.3390/nu16020321. Exploring the Impact of Protein Supplement Source on Body Composition in Women Practicing Anaerobic Resistance Exercise: A Pilot Study. Ballesteros-Torres JM(1), Escalante-Aburto A(2)(3), Villarreal-Arce ME(3), Caballero-Prado CJ(3).

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